AutismKB 2.0

Annotation Detail for HOXB7


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Basic Information Top
Gene Symbol:HOXB7 ( HHO.C1,HOX2,HOX2C,Hox-2.3 )
Gene Full Name: homeobox B7
Band: 17q21.32
Quick LinksEntrez ID:3217; OMIM: 142962; Uniprot ID:HXB7_HUMAN; ENSEMBL ID: ENSG00000120087; HGNC ID: 5118
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor6 / 9635962
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal17 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor8 / 12494964
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone3 / 7165541
bone marrow0 / 488010 
brain2 / 11009891
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine18 / 23447276
kidney5 / 21177723
larynx0 / 241450 
liver6 / 20774328
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle6 / 10771555
nerve0 / 157680 
ovary2 / 10205119
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate3 / 18934515
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach3 / 9661931
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204779_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts34.25
Adipocyte10.45
AdrenalCortex13.05
Adrenalgland10.7
Amygdala10.3
Appendix11.45
AtrioventricularNode10.55
BDCA4+_DentriticCells10.7
Bonemarrow11.5
BronchialEpithelialCells8.55
CD105+_Endothelial10.3
CD14+_Monocytes10.65
CD19+_BCells(neg._sel.)10.25
CD33+_Myeloid12.9
CD34+12.4
CD4+_Tcells9.4
CD56+_NKCells10.25
CD71+_EarlyErythroid9.95
CD8+_Tcells9.35
CardiacMyocytes15.1
Caudatenucleus8.75
Cerebellum7.95
CerebellumPeduncles11.4
CiliaryGanglion12.7
CingulateCortex10.25
Colorectaladenocarcinoma971.45
DorsalRootGanglion10.2
FetalThyroid9.75
Fetalbrain10.15
Fetalliver8.25
Fetallung7.85
GlobusPallidus8.05
Heart13.9
Hypothalamus10.15
Kidney12.7
Leukemia_chronicMyelogenousK-5628.7
Leukemia_promyelocytic-HL-609.35
Leukemialymphoblastic(MOLT-4)7.25
Liver15.85
Lung17.75
Lymphnode8.4
Lymphoma_burkitts(Daudi)12.85
Lymphoma_burkitts(Raji)33.15
MedullaOblongata8.7
OccipitalLobe8.75
OlfactoryBulb28.15
Ovary7.85
Pancreas57.3
PancreaticIslet10.75
ParietalLobe11.25
Pituitary10.8
Placenta10.2
Pons10
PrefrontalCortex10.95
Prostate11.6
Salivarygland8.3
SkeletalMuscle15.55
Skin10
SmoothMuscle11.25
Spinalcord25.7
SubthalamicNucleus9.35
SuperiorCervicalGanglion12.25
TemporalLobe9.25
Testis7.8
TestisGermCell8.3
TestisIntersitial8.45
TestisLeydigCell10.15
TestisSeminiferousTubule8.55
Thalamus10.2
Thymus7.6
Thyroid12.5
Tongue11.05
Tonsil9.85
Trachea7.75
TrigeminalGanglion27.35
Uterus12.1
UterusCorpus9.05
WholeBlood10.4
Wholebrain8
colon63.1
pineal_day11.82
pineal_night11.78
retina12.1
small_intestine19.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P49810
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.01 ± 0.53
Basal Forebrain7.05 ± 0.49
Basal Part of Pons7.29 ± 0.34
Cerebellar Cortex6.66 ± 0.63
Cerebellar Nuclei7.17 ± 0.49
Claustrum7.38 ± 0.87
Epithalamus6.3 ± 0.64
Frontal Lobe6.97 ± 0.67
Globus Pallidus7.68 ± 0.64
Hypothalamus6.55 ± 0.56
Insula6.83 ± 0.55
Limbic Lobe7.19 ± 0.73
Mesencephalon6.83 ± 0.53
Myelencephalon7.06 ± 0.71
Occipital Lobe7.05 ± 0.74
Parietal Lobe6.81 ± 0.65
Pontine Tegmentum6.71 ± 0.64
Striatum7.14 ± 0.76
Subthalamus6.2 ± 0.15
Temporal Lobe6.83 ± 0.66
Thalamus7.07 ± 0.55
White Matter7.1 ± 0.47
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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