AutismKB 2.0

Annotation Detail for HOXD9


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Basic Information Top
Gene Symbol:HOXD9 ( HOX4,HOX4C,Hox-4.3,Hox-5.2 )
Gene Full Name: homeobox D9
Band: 2q31.1
Quick LinksEntrez ID:3235; OMIM: 142982; Uniprot ID:HXD9_HUMAN; ENSEMBL ID: ENSG00000128709; HGNC ID: 5140
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult11 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal27 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine1 / 2344724
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205604_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.05
Adipocyte7.75
AdrenalCortex8.05
Adrenalgland6.55
Amygdala8.45
Appendix8
AtrioventricularNode5.9
BDCA4+_DentriticCells8.85
Bonemarrow8
BronchialEpithelialCells7.85
CD105+_Endothelial7.95
CD14+_Monocytes8.4
CD19+_BCells(neg._sel.)8.45
CD33+_Myeloid10.2
CD34+10
CD4+_Tcells8.65
CD56+_NKCells9.5
CD71+_EarlyErythroid7.25
CD8+_Tcells7.75
CardiacMyocytes10
Caudatenucleus7.05
Cerebellum6.9
CerebellumPeduncles8.85
CiliaryGanglion5.4
CingulateCortex8
Colorectaladenocarcinoma9.9
DorsalRootGanglion5.9
FetalThyroid7.6
Fetalbrain7.9
Fetalliver6.6
Fetallung6.65
GlobusPallidus5.65
Heart10.75
Hypothalamus8.25
Kidney6.25
Leukemia_chronicMyelogenousK-5627.15
Leukemia_promyelocytic-HL-607
Leukemialymphoblastic(MOLT-4)6.35
Liver10.25
Lung9.15
Lymphnode6.85
Lymphoma_burkitts(Daudi)9.95
Lymphoma_burkitts(Raji)11.25
MedullaOblongata7.35
OccipitalLobe6.8
OlfactoryBulb6.2
Ovary5.3
Pancreas6.2
PancreaticIslet8.15
ParietalLobe8.15
Pituitary9.2
Placenta7.5
Pons7.45
PrefrontalCortex9.55
Prostate17.35
Salivarygland6.2
SkeletalMuscle8.85
Skin6.2
SmoothMuscle8.65
Spinalcord8.4
SubthalamicNucleus7
SuperiorCervicalGanglion9.65
TemporalLobe7.15
Testis7.65
TestisGermCell6.65
TestisIntersitial6.6
TestisLeydigCell8.2
TestisSeminiferousTubule7
Thalamus7.7
Thymus6.3
Thyroid10.05
Tongue9.35
Tonsil7.7
Trachea6.4
TrigeminalGanglion7.75
Uterus26.6
UterusCorpus10.3
WholeBlood8.75
Wholebrain6.7
colon8
pineal_day9.68
pineal_night9.86
retina9.65
small_intestine7.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_936_PI416379584
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.43 ± 1.04
Basal Forebrain2 ± 0.25
Basal Part of Pons1.62 ± 0.39
Cerebellar Cortex1.84 ± 0.78
Cerebellar Nuclei2.32 ± 0.67
Claustrum2.92 ± 0.9
Epithalamus1.7 ± 0.81
Frontal Lobe1.85 ± 0.71
Globus Pallidus2.57 ± 0.24
Hypothalamus2 ± 0.67
Insula1.83 ± 0.56
Limbic Lobe2 ± 0.71
Mesencephalon2.17 ± 0.68
Myelencephalon2.04 ± 0.7
Occipital Lobe1.96 ± 0.52
Parietal Lobe2.03 ± 0.75
Pontine Tegmentum2.01 ± 0.74
Striatum2.18 ± 0.59
Subthalamus2.18 ± 0.78
Temporal Lobe1.88 ± 0.71
Thalamus1.94 ± 0.63
White Matter2.47 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hoxd9CBCerebellum100
100
Hoxd9CTXCerebral cortex100
100
Hoxd9HIPHippocampal region99.45
100
Hoxd9HPFHippocampal formation100
100
Hoxd9HYHypothalamus100
100
Hoxd9LSXLateral septal complex100
100
Hoxd9MBMidbrain100
100
Hoxd9MYMedulla100
100
Hoxd9OLFOlfactory bulb100
100
Hoxd9PPons100
100
Hoxd9PALPallidum100
100
Hoxd9RHPRetrohippocampal region100
100
Hoxd9sAMYStriatum-like amygdalar nuclei100
100
Hoxd9STRStriatum100
100
Hoxd9STRdStriatum dorsal region100
100
Hoxd9STRvStriatum ventral region100
100
Hoxd9THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018