AutismKB 2.0

Annotation Detail for HOXD10


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HOXD10 ( HOX4,HOX4D,HOX4E,Hox-4.4 )
Gene Full Name: homeobox D10
Band: 2q31.1
Quick LinksEntrez ID:3236; OMIM: 142984; Uniprot ID:HXD10_HUMAN; ENSEMBL ID: ENSG00000128710; HGNC ID: 5133
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult15 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal15 / 33603074
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain1 / 11009890 
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine3 / 23447212
kidney7 / 21177733
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate6 / 18934531
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207373_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.9
Adipocyte4.75
AdrenalCortex5.15
Adrenalgland4.1
Amygdala5.05
Appendix5.1
AtrioventricularNode3.7
BDCA4+_DentriticCells5.15
Bonemarrow4.8
BronchialEpithelialCells4.7
CD105+_Endothelial4.85
CD14+_Monocytes5.05
CD19+_BCells(neg._sel.)4.95
CD33+_Myeloid6.05
CD34+6.1
CD4+_Tcells4.8
CD56+_NKCells5.45
CD71+_EarlyErythroid4.55
CD8+_Tcells4.45
CardiacMyocytes6.45
Caudatenucleus4.25
Cerebellum3.9
CerebellumPeduncles5.5
CiliaryGanglion3.35
CingulateCortex4.95
Colorectaladenocarcinoma4.8
DorsalRootGanglion3.7
FetalThyroid4.7
Fetalbrain4.8
Fetalliver4.2
Fetallung3.9
GlobusPallidus3.5
Heart6.05
Hypothalamus5.2
Kidney4
Leukemia_chronicMyelogenousK-5624.35
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.85
Liver6.5
Lung5.25
Lymphnode4.15
Lymphoma_burkitts(Daudi)6.2
Lymphoma_burkitts(Raji)6.8
MedullaOblongata4.45
OccipitalLobe4.3
OlfactoryBulb3.8
Ovary3.2
Pancreas3.85
PancreaticIslet5.15
ParietalLobe7.85
Pituitary5.65
Placenta5
Pons4.6
PrefrontalCortex5.95
Prostate5.7
Salivarygland3.85
SkeletalMuscle5.75
Skin3.65
SmoothMuscle5.45
Spinalcord5.15
SubthalamicNucleus4.4
SuperiorCervicalGanglion5.55
TemporalLobe4.4
Testis4.1
TestisGermCell3.95
TestisIntersitial4
TestisLeydigCell4.75
TestisSeminiferousTubule4.1
Thalamus4.85
Thymus3.75
Thyroid6
Tongue4.8
Tonsil4.65
Trachea4.05
TrigeminalGanglion4.85
Uterus7.7
UterusCorpus6.65
WholeBlood5.25
Wholebrain4.1
colon4.75
pineal_day5.82
pineal_night5.74
retina5.775
small_intestine4.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9301_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.26 ± 1.01
Basal Forebrain1.83 ± 0.19
Basal Part of Pons1.64 ± 0.53
Cerebellar Cortex1.7 ± 0.77
Cerebellar Nuclei2.04 ± 0.66
Claustrum2.8 ± 0.97
Epithalamus1.56 ± 0.66
Frontal Lobe1.62 ± 0.6
Globus Pallidus2.6 ± 1.12
Hypothalamus1.78 ± 0.68
Insula1.72 ± 0.46
Limbic Lobe1.84 ± 0.72
Mesencephalon1.99 ± 0.75
Myelencephalon1.82 ± 0.67
Occipital Lobe1.87 ± 0.62
Parietal Lobe1.83 ± 0.71
Pontine Tegmentum1.89 ± 0.74
Striatum2.04 ± 0.67
Subthalamus1.94 ± 0.67
Temporal Lobe1.73 ± 0.67
Thalamus1.79 ± 0.67
White Matter2.17 ± 0.31
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018