Annotation Detail for APC
Basic Information Top
| Gene Symbol: | APC ( BTPS2,DP2,DP2.5,DP3,GS ) |
|---|---|
| Gene Full Name: | adenomatous polyposis coli |
| Band: | 5q22.2 |
| Quick Links | Entrez ID:324; OMIM: 611731; Uniprot ID:APC_HUMAN; ENSEMBL ID: ENSG00000134982; HGNC ID: 583 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.158932
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 81 / 564012 | 143 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 6 / 23620 | 254 |  |
| juvenile | 1 / 55556 | 17 | |
| adult | 82 / 1939121 | 42 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 7 / 263845 | 26 | |
| glioma | 5 / 106883 | 46 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 4 / 95842 | 41 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 3 / 71755 | 41 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 312 / 3360307 | 92 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 1 / 124949 | 8 |  |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 2 / 29757 | 67 | |
| blood | 5 / 123478 | 40 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 139 / 1100989 | 126 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 2 / 16212 | 123 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 9 / 211054 | 42 | |
| heart | 4 / 89626 | 44 | |
| intestine | 5 / 234472 | 21 | |
| kidney | 7 / 211777 | 33 | |
| larynx | 2 / 24145 | 82 | |
| liver | 5 / 207743 | 24 | |
| lung | 9 / 336974 | 26 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 10 / 91610 | 109 | |
| mammary gland | 10 / 153271 | 65 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 7 / 107715 | 64 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 5 / 214812 | 23 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 6 / 210574 | 28 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 0 / 96619 | 0 | |
| testis | 27 / 330442 | 81 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 10 / 232878 | 42 | |
| vascular | 4 / 51780 | 77 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 203527_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 11.55 | |
| Adipocyte | 10.2 | |
| AdrenalCortex | 11.45 | |
| Adrenalgland | 8.9 | |
| Amygdala | 22.9 | |
| Appendix | 11.4 | |
| AtrioventricularNode | 8 | |
| BDCA4+_DentriticCells | 9.1 | |
| Bonemarrow | 10.95 | |
| BronchialEpithelialCells | 9.2 | |
| CD105+_Endothelial | 9.4 | |
| CD14+_Monocytes | 10.2 | |
| CD19+_BCells(neg._sel.) | 10.25 | |
| CD33+_Myeloid | 12.2 | |
| CD34+ | 11.25 | |
| CD4+_Tcells | 10.3 | |
| CD56+_NKCells | 11.3 | |
| CD71+_EarlyErythroid | 9.55 | |
| CD8+_Tcells | 9.25 | |
| CardiacMyocytes | 15.55 | |
| Caudatenucleus | 14.3 | |
| Cerebellum | 13.05 | |
| CerebellumPeduncles | 13 | |
| CiliaryGanglion | 7.7 | |
| CingulateCortex | 14.4 | |
| Colorectaladenocarcinoma | 10.4 | |
| DorsalRootGanglion | 8.55 | |
| FetalThyroid | 10.2 | |
| Fetalbrain | 40.8 | |
| Fetalliver | 9.3 | |
| Fetallung | 8.65 | |
| GlobusPallidus | 8.3 | |
| Heart | 14.9 | |
| Hypothalamus | 17.6 | |
| Kidney | 9 | |
| Leukemia_chronicMyelogenousK-562 | 8.9 | |
| Leukemia_promyelocytic-HL-60 | 8.75 | |
| Leukemialymphoblastic(MOLT-4) | 8.45 | |
| Liver | 14.6 | |
| Lung | 11.1 | |
| Lymphnode | 8.8 | |
| Lymphoma_burkitts(Daudi) | 12.25 | |
| Lymphoma_burkitts(Raji) | 15.4 | |
| MedullaOblongata | 10.65 | |
| OccipitalLobe | 11.3 | |
| OlfactoryBulb | 9.2 | |
| Ovary | 7 | |
| Pancreas | 9.4 | |
| PancreaticIslet | 11.5 | |
| ParietalLobe | 13.05 | |
| Pituitary | 12.45 | |
| Placenta | 10.55 | |
| Pons | 10.3 | |
| PrefrontalCortex | 21.85 | |
| Prostate | 12.05 | |
| Salivarygland | 8.45 | |
| SkeletalMuscle | 13.9 | |
| Skin | 9.15 | |
| SmoothMuscle | 11 | |
| Spinalcord | 17.1 | |
| SubthalamicNucleus | 12.85 | |
| SuperiorCervicalGanglion | 15.5 | |
| TemporalLobe | 10.95 | |
| Testis | 9.1 | |
| TestisGermCell | 8.6 | |
| TestisIntersitial | 8.5 | |
| TestisLeydigCell | 10.45 | |
| TestisSeminiferousTubule | 8.95 | |
| Thalamus | 11.9 | |
| Thymus | 7.7 | |
| Thyroid | 12.45 | |
| Tongue | 10.2 | |
| Tonsil | 10.35 | |
| Trachea | 9.25 | |
| TrigeminalGanglion | 11.1 | |
| Uterus | 8.4 | |
| UterusCorpus | 10.95 | |
| WholeBlood | 11.45 | |
| Wholebrain | 9.05 | |
| colon | 10.1 | |
| pineal_day | 12.82 | |
| pineal_night | 12.44 | |
| retina | 14.425 | |
| small_intestine | 9.6 | |
- Probe name: A_23_P70213
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 6.2 ± 0.47 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.78 ± 0.23 | |
| Basal Part of Pons | 6.53 ± 0.23 | |
| Cerebellar Cortex | 5.56 ± 0.3 | |
| Cerebellar Nuclei | 5.55 ± 0.61 | |
| Claustrum | 5.97 ± 0.53 | |
| Epithalamus | 5.36 ± 0.3 | |
| Frontal Lobe | 6 ± 0.44 | |
| Globus Pallidus | 5.24 ± 0.54 | |
| Hypothalamus | 5.55 ± 0.63 | |
| Insula | 5.94 ± 0.35 | |
| Limbic Lobe | 6.15 ± 0.54 | |
| Mesencephalon | 5.66 ± 0.48 | |
| Myelencephalon | 5.87 ± 0.5 | |
| Occipital Lobe | 5.82 ± 0.49 | |
| Parietal Lobe | 5.9 ± 0.46 | |
| Pontine Tegmentum | 5.8 ± 0.44 | |
| Striatum | 5.65 ± 0.56 | |
| Subthalamus | 5.41 ± 0.62 | |
| Temporal Lobe | 6.08 ± 0.32 | |
| Thalamus | 5.97 ± 0.34 | |
| White Matter | 3.88 ± 0.82 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Apc | CB | Cerebellum | 28.99 | |
| 31.99 | | |||
| Apc | CTX | Cerebral cortex | 100 | |
| 90.05 | | |||
| Apc | HIP | Hippocampal region | 59.59 | |
| 82.18 | | |||
| Apc | HPF | Hippocampal formation | 86.27 | |
| 88.24 | | |||
| Apc | HY | Hypothalamus | 87.52 | |
| 55.84 | | |||
| Apc | LSX | Lateral septal complex | 88.82 | |
| 48.58 | | |||
| Apc | MB | Midbrain | 72.11 | |
| 57.93 | | |||
| Apc | MY | Medulla | 75.01 | |
| 77.96 | | |||
| Apc | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Apc | P | Pons | 75.28 | |
| 72.44 | | |||
| Apc | PAL | Pallidum | 79.82 | |
| 66.99 | | |||
| Apc | RHP | Retrohippocampal region | 100 | |
| 93.8 | | |||
| Apc | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 73.27 | | |||
| Apc | STR | Striatum | 63.96 | |
| 39.62 | | |||
| Apc | STRd | Striatum dorsal region | 50.76 | |
| 32.1 | | |||
| Apc | STRv | Striatum ventral region | 73.35 | |
| 43.9 | | |||
| Apc | TH | Thalamus | 100 | |
| 81.77 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| APC_HUMAN_188 | 7 | 188 | 194 | QLEYEAR | PRIDE |
| APC_HUMAN_64 | 8 | 64 | 71 | GQIDLLER | PRIDE |
| PAp00009250 | 24 | 2103 | 2126 | AIQEGANSIVSSLHQAAAAACLSR | Peptide Atlas |