AutismKB 2.0

Annotation Detail for HPCAL1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HPCAL1 ( BDR1,HLP2,VILIP-3 )
Gene Full Name: hippocalcin-like 1
Band: 2p25.1
Quick LinksEntrez ID:3241; OMIM: 600207; Uniprot ID:HPCL1_HUMAN; ENSEMBL ID: ENSG00000115756; HGNC ID: 5145
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile10 / 55556179
adult109 / 193912156
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor7 / 9417874
cervical tumor10 / 34366290
chondrosarcoma5 / 8282360
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor12 / 119369100
germ cell tumor12 / 26384545
glioma7 / 10688365
head and neck tumor8 / 13630258
kidney tumor4 / 6895958
leukemia12 / 95842125
liver tumor9 / 9635993
lung tumor14 / 103127135
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal153 / 336030745
ovarian tumor1 / 7668213
pancreatic tumor23 / 104616219
primitive neuroectodermal tumor of the CNS18 / 125680143
prostate cancer4 / 10268038
retinoblastoma3 / 4635664
skin tumor10 / 12494980
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder1 / 2975733
blood11 / 12347889
bone2 / 7165527
bone marrow2 / 4880140
brain110 / 110098999
cervix20 / 48171415
connective tissue9 / 14925560
ear1 / 1621261
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye16 / 21105475
heart3 / 8962633
intestine14 / 23447259
kidney9 / 21177742
larynx0 / 241450 
liver11 / 20774352
lung26 / 33697477
lymph0 / 442700 
lymph node6 / 9161065
mammary gland8 / 15327152
mouth0 / 670520 
muscle1 / 1077159
nerve2 / 15768126
ovary6 / 10205158
pancreas27 / 214812125
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate4 / 18934521
salivary gland4 / 20155198
skin10 / 21057447
spleen1 / 5395218
stomach8 / 9661982
testis16 / 33044248
thymus2 / 8113124
thyroid4 / 4747384
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord0 / 136800 
uterus16 / 23287868
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205462_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.35
Adipocyte16.2
AdrenalCortex17.6
Adrenalgland16.1
Amygdala126.65
Appendix12
AtrioventricularNode8.55
BDCA4+_DentriticCells35.35
Bonemarrow17.6
BronchialEpithelialCells15.5
CD105+_Endothelial10
CD14+_Monocytes30.9
CD19+_BCells(neg._sel.)22.2
CD33+_Myeloid53.3
CD34+15.65
CD4+_Tcells69
CD56+_NKCells61.05
CD71+_EarlyErythroid11.15
CD8+_Tcells56.85
CardiacMyocytes21
Caudatenucleus19.15
Cerebellum319.25
CerebellumPeduncles588.65
CiliaryGanglion10.75
CingulateCortex30.55
Colorectaladenocarcinoma87.9
DorsalRootGanglion9.65
FetalThyroid15.85
Fetalbrain13.8
Fetalliver14.15
Fetallung45.5
GlobusPallidus25.35
Heart22.95
Hypothalamus58.1
Kidney14.7
Leukemia_chronicMyelogenousK-56235.5
Leukemia_promyelocytic-HL-6015.35
Leukemialymphoblastic(MOLT-4)14.7
Liver21.35
Lung442.45
Lymphnode15.9
Lymphoma_burkitts(Daudi)18.1
Lymphoma_burkitts(Raji)23.75
MedullaOblongata21.35
OccipitalLobe42.2
OlfactoryBulb12.6
Ovary8.55
Pancreas14.6
PancreaticIslet15.1
ParietalLobe38.05
Pituitary22.8
Placenta42.85
Pons18.25
PrefrontalCortex174.8
Prostate22
Salivarygland8.75
SkeletalMuscle18.9
Skin10.25
SmoothMuscle18.25
Spinalcord18.4
SubthalamicNucleus26.05
SuperiorCervicalGanglion13.35
TemporalLobe30.25
Testis33.5
TestisGermCell28.9
TestisIntersitial14.2
TestisLeydigCell14.4
TestisSeminiferousTubule13.65
Thalamus19.45
Thymus13.55
Thyroid40.55
Tongue15.1
Tonsil15.65
Trachea13
TrigeminalGanglion12.6
Uterus22.9
UterusCorpus13.65
WholeBlood95.25
Wholebrain127.65
colon16.2
pineal_day138.12
pineal_night141.02
retina56.475
small_intestine15.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P5831
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.73 ± 0.91
Basal Forebrain6.91 ± 0.65
Basal Part of Pons6.22 ± 0.67
Cerebellar Cortex7.96 ± 0.48
Cerebellar Nuclei6.85 ± 0.65
Claustrum6.08 ± 1.36
Epithalamus7.2 ± 1.17
Frontal Lobe7.23 ± 0.88
Globus Pallidus5.06 ± 0.68
Hypothalamus8.17 ± 0.86
Insula7.71 ± 0.57
Limbic Lobe6.47 ± 1.03
Mesencephalon6.76 ± 1.1
Myelencephalon6.91 ± 1.16
Occipital Lobe5.84 ± 1.26
Parietal Lobe6.86 ± 0.73
Pontine Tegmentum7.17 ± 1.05
Striatum4.88 ± 0.88
Subthalamus6.35 ± 0.59
Temporal Lobe7.35 ± 0.71
Thalamus7.22 ± 0.86
White Matter5.08 ± 0.45
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hpcal1CBCerebellum49.46
100
Hpcal1CTXCerebral cortex13.68
14.75
Hpcal1HIPHippocampal region17.05
22.91
Hpcal1HPFHippocampal formation24.8
35.55
Hpcal1HYHypothalamus32.19
36.69
Hpcal1LSXLateral septal complex9.38
9.07
Hpcal1MBMidbrain28.68
33.24
Hpcal1MYMedulla41.64
65.85
Hpcal1OLFOlfactory bulb41.61
48.45
Hpcal1PPons32.59
45.61
Hpcal1PALPallidum21.59
26.49
Hpcal1RHPRetrohippocampal region36.6
50.72
Hpcal1sAMYStriatum-like amygdalar nuclei33.2
35.98
Hpcal1STRStriatum11.31
12.46
Hpcal1STRdStriatum dorsal region9.1
9.63
Hpcal1STRvStriatum ventral region10.89
10.74
Hpcal1THThalamus8.5
9.3
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
HPCL1_HUMAN_0 0 0 0 LSLEEFIR PRIDE
HPCL1_HUMAN_118 12 118 129 SEMLEIVQAIYK PRIDE
HPCL1_HUMAN_163 8 163 170 LSLEEFIR PRIDE
HPCL1_HUMAN_7 10 7 16 LRPEVLQDLR PRIDE
PAp00009785 14 37 50 DCPTGHLTVDEFKK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved