AutismKB 2.0

Annotation Detail for HPX


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Basic Information Top
Gene Symbol:HPX ( FLJ56652,HX )
Gene Full Name: hemopexin
Band: 11p15.4
Quick LinksEntrez ID:3263; OMIM: 142290; Uniprot ID:HEMO_HUMAN; ENSEMBL ID: ENSG00000110169; HGNC ID: 5171
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus63 / 564012111
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult154 / 193912179
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor16 / 96359166
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal244 / 336030772
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain6 / 11009895
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver199 / 207743957
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland11 / 15327171
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen3 / 5395255
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 39763_at
Cell line Expression level Expression bar
721_B_lymphoblasts3.65
Adipocyte2.85
AdrenalCortex2.85
Adrenalgland2.45
Amygdala3.05
Appendix2.85
AtrioventricularNode2.3
BDCA4+_DentriticCells3.25
Bonemarrow2.8
BronchialEpithelialCells2.85
CD105+_Endothelial2.8
CD14+_Monocytes3.05
CD19+_BCells(neg._sel.)3.05
CD33+_Myeloid3.7
CD34+3.6
CD4+_Tcells3.15
CD56+_NKCells3.45
CD71+_EarlyErythroid2.6
CD8+_Tcells2.8
CardiacMyocytes3.5
Caudatenucleus2.55
Cerebellum2.35
CerebellumPeduncles3.2
CiliaryGanglion1.9
CingulateCortex2.9
Colorectaladenocarcinoma2.85
DorsalRootGanglion2.1
FetalThyroid2.75
Fetalbrain2.9
Fetalliver640.8
Fetallung120.8
GlobusPallidus2.05
Heart3.5
Hypothalamus3.2
Kidney2.3
Leukemia_chronicMyelogenousK-5622.55
Leukemia_promyelocytic-HL-602.5
Leukemialymphoblastic(MOLT-4)2.35
Liver6872.4
Lung3.2
Lymphnode2.55
Lymphoma_burkitts(Daudi)3.65
Lymphoma_burkitts(Raji)4.35
MedullaOblongata2.65
OccipitalLobe2.55
OlfactoryBulb2.25
Ovary1.85
Pancreas2.3
PancreaticIslet3.1
ParietalLobe2.95
Pituitary3.35
Placenta3
Pons2.65
PrefrontalCortex3.6
Prostate3.7
Salivarygland2.3
SkeletalMuscle3.1
Skin2.15
SmoothMuscle3.3
Spinalcord3.05
SubthalamicNucleus2.8
SuperiorCervicalGanglion3.1
TemporalLobe2.55
Testis2.5
TestisGermCell2.4
TestisIntersitial2.35
TestisLeydigCell2.8
TestisSeminiferousTubule2.45
Thalamus2.9
Thymus2.3
Thyroid3.65
Tongue2.75
Tonsil2.75
Trachea2.4
TrigeminalGanglion2.75
Uterus2.35
UterusCorpus2.5
WholeBlood3.2
Wholebrain2.5
colon2.9
pineal_day3.5
pineal_night3.62
retina3.5
small_intestine2.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_242_PI417507815
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.25 ± 1.03
Basal Forebrain1.69 ± 0.3
Basal Part of Pons1.55 ± 0.54
Cerebellar Cortex1.46 ± 0.62
Cerebellar Nuclei2.01 ± 0.74
Claustrum2.69 ± 1.05
Epithalamus1.41 ± 0.87
Frontal Lobe1.57 ± 0.78
Globus Pallidus2.28 ± 0.53
Hypothalamus1.8 ± 0.96
Insula1.36 ± 0.42
Limbic Lobe1.82 ± 0.78
Mesencephalon1.92 ± 0.94
Myelencephalon1.78 ± 0.82
Occipital Lobe1.9 ± 0.92
Parietal Lobe1.81 ± 1.04
Pontine Tegmentum1.78 ± 0.8
Striatum1.97 ± 0.83
Subthalamus1.69 ± 0.68
Temporal Lobe1.73 ± 0.84
Thalamus1.69 ± 0.65
White Matter1.84 ± 0.42
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
HEMO_HUMAN_131 21 131 151 LLQDEFPGIPSPLDAAVECHR PRIDE
HEMO_HUMAN_198 11 198 208 YYCFQGNQFLR PRIDE
HEMO_HUMAN_290 28 290 317 DGWHSWPIAHQWPQGPSAVDAAFSWEEK PRIDE
HEMO_HUMAN_348 24 348 371 EVGTPHGIILDSVDAAFICPGSSR PRIDE
HEMO_HUMAN_387 16 387 402 SGAQATWTELPWPHEK PRIDE
HEMO_HUMAN_72 6 72 77 GEFVWK PRIDE
HEMO_HUMAN_92 11 92 102 NFPSPVDAAFR PRIDE
PAp00024178 16 447 462 ALPQPQNVTSLLGCTH Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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