AutismKB 2.0

Annotation Detail for HRAS


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Basic Information Top
Gene Symbol:HRAS ( C-BAS/HAS,C-H-RAS,C-HA-RAS1,CTLO,H-RASIDX,HAMSV,HRAS1,K-RAS,N-RAS,RASH1 )
Gene Full Name: v-Ha-ras Harvey rat sarcoma viral oncogene homolog
Band: 11p15.5
Quick LinksEntrez ID:3265; OMIM: 190020; Uniprot ID:RASH_HUMAN; ENSEMBL ID: ENSG00000174775; HGNC ID: 5173
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult45 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma10 / 82823120
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor3 / 26384511
glioma5 / 10688346
head and neck tumor5 / 13630236
kidney tumor5 / 6895972
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal63 / 336030718
ovarian tumor1 / 7668213
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone8 / 71655111
bone marrow0 / 488010 
brain17 / 110098915
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye10 / 21105447
heart1 / 8962611
intestine5 / 23447221
kidney7 / 21177733
larynx1 / 2414541
liver2 / 2077439
lung9 / 33697426
lymph1 / 4427022
lymph node3 / 9161032
mammary gland3 / 15327119
mouth8 / 67052119
muscle3 / 10771527
nerve0 / 157680 
ovary2 / 10205119
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland2 / 2015599
skin4 / 21057418
spleen0 / 539520 
stomach2 / 9661920
testis5 / 33044215
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212983_at
Cell line Expression level Expression bar
721_B_lymphoblasts130.6
Adipocyte52.2
AdrenalCortex36.5
Adrenalgland24.45
Amygdala144.4
Appendix29.65
AtrioventricularNode17.75
BDCA4+_DentriticCells62.95
Bonemarrow22.25
BronchialEpithelialCells248.8
CD105+_Endothelial76.7
CD14+_Monocytes38
CD19+_BCells(neg._sel.)70.1
CD33+_Myeloid67.9
CD34+54.95
CD4+_Tcells50
CD56+_NKCells64.15
CD71+_EarlyErythroid38.25
CD8+_Tcells38.1
CardiacMyocytes133.65
Caudatenucleus173.25
Cerebellum66.3
CerebellumPeduncles110.85
CiliaryGanglion18.6
CingulateCortex79.05
Colorectaladenocarcinoma150.05
DorsalRootGanglion24.4
FetalThyroid55.25
Fetalbrain102.35
Fetalliver23.1
Fetallung38.9
GlobusPallidus48.1
Heart146.4
Hypothalamus127.8
Kidney25.35
Leukemia_chronicMyelogenousK-56222.15
Leukemia_promyelocytic-HL-6031.15
Leukemialymphoblastic(MOLT-4)42.5
Liver55.8
Lung81.25
Lymphnode21.5
Lymphoma_burkitts(Daudi)64.8
Lymphoma_burkitts(Raji)123.1
MedullaOblongata80.7
OccipitalLobe96.6
OlfactoryBulb48.5
Ovary17.05
Pancreas27.1
PancreaticIslet49.6
ParietalLobe65.8
Pituitary46.45
Placenta47.15
Pons74.9
PrefrontalCortex151
Prostate92.4
Salivarygland20.6
SkeletalMuscle62.3
Skin32.4
SmoothMuscle103.35
Spinalcord79.1
SubthalamicNucleus53.15
SuperiorCervicalGanglion28.8
TemporalLobe129.95
Testis44.25
TestisGermCell17.3
TestisIntersitial20.95
TestisLeydigCell20.9
TestisSeminiferousTubule21.2
Thalamus121.9
Thymus42.25
Thyroid94.3
Tongue109.5
Tonsil44.45
Trachea26.2
TrigeminalGanglion30.35
Uterus36.55
UterusCorpus34.25
WholeBlood32.35
Wholebrain149.7
colon20.55
pineal_day157.3
pineal_night180.48
retina107.6
small_intestine23.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P98183
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.73 ± 0.98
Basal Forebrain7.35 ± 0.41
Basal Part of Pons7.65 ± 0.66
Cerebellar Cortex7.18 ± 0.56
Cerebellar Nuclei7.07 ± 0.39
Claustrum6.69 ± 0.88
Epithalamus7.44 ± 0.36
Frontal Lobe7.51 ± 0.51
Globus Pallidus7.06 ± 0.41
Hypothalamus7.6 ± 0.83
Insula7.62 ± 0.35
Limbic Lobe7.15 ± 0.74
Mesencephalon7.22 ± 0.5
Myelencephalon7.28 ± 0.64
Occipital Lobe6.5 ± 0.65
Parietal Lobe7.16 ± 0.51
Pontine Tegmentum7.26 ± 0.53
Striatum7.64 ± 0.61
Subthalamus7.51 ± 0.54
Temporal Lobe7.51 ± 0.48
Thalamus7.24 ± 0.44
White Matter6.46 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hras1CBCerebellum18.58
33.15
Hras1CTXCerebral cortex79.1
87.5
Hras1HIPHippocampal region69.48
100
Hras1HPFHippocampal formation80.53
100
Hras1HYHypothalamus61.46
67.56
Hras1LSXLateral septal complex18.88
19.26
Hras1MBMidbrain28.21
36.88
Hras1MYMedulla20
39.23
Hras1OLFOlfactory bulb66.85
95.94
Hras1PPons38.15
61.28
Hras1PALPallidum52.04
70.78
Hras1RHPRetrohippocampal region100
100
Hras1sAMYStriatum-like amygdalar nuclei75.21
82.23
Hras1STRStriatum93.96
100
Hras1STRdStriatum dorsal region100
100
Hras1STRvStriatum ventral region100
100
Hras1THThalamus47.75
60.42
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00006948 26 17 42 SALTIQLIQNHFVDEYDPTIEDSYRK Peptide Atlas
RASH_HUMAN_149 12 149 160 QGVEDAFYTLVR PRIDE
RASH_HUMAN_16 26 16 41 SALTIQLIQNHFVDEYDPTIEDSYRK PRIDE
RASH_HUMAN_169 16 169 184 KLNPPDESGPGCMSCK PRIDE
RASH_HUMAN_170 15 170 184 LNPPDESGPGCMSCK PRIDE
RASH_HUMAN_5 11 5 15 LVVVGAGGVGK PRIDE
RASH_HUMAN_73 15 73 87 TGEGFLCVFAINNTK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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