AutismKB 2.0

Annotation Detail for ERAS


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Basic Information Top
Gene Symbol:ERAS ( HRAS2,HRASP,MGC126691,MGC126693 )
Gene Full Name: ES cell expressed Ras
Band: Xp11.23
Quick LinksEntrez ID:3266; OMIM: 300437; Uniprot ID:RASE_HUMAN; ENSEMBL ID: ENSG00000187682; HGNC ID: 5174
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_4997_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.08 ± 0.72
Basal Forebrain5.84 ± 0.46
Basal Part of Pons5.73 ± 0.67
Cerebellar Cortex5.44 ± 0.52
Cerebellar Nuclei5.74 ± 0.38
Claustrum6.42 ± 0.87
Epithalamus4.84 ± 0.62
Frontal Lobe5.62 ± 0.65
Globus Pallidus6.14 ± 0.54
Hypothalamus5.35 ± 0.49
Insula5.71 ± 0.52
Limbic Lobe5.87 ± 0.66
Mesencephalon5.81 ± 0.56
Myelencephalon5.77 ± 0.68
Occipital Lobe5.77 ± 0.77
Parietal Lobe5.66 ± 0.62
Pontine Tegmentum5.54 ± 0.59
Striatum5.82 ± 0.74
Subthalamus5.24 ± 1.01
Temporal Lobe5.61 ± 0.72
Thalamus5.72 ± 0.52
White Matter5.94 ± 0.51
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
ErasCBCerebellum0.37
0.55
ErasCTXCerebral cortex0.24
0.34
ErasHIPHippocampal region0.13
0.16
ErasHPFHippocampal formation0.11
0.12
ErasHYHypothalamus0.07
0.12
ErasLSXLateral septal complex0
0
ErasMBMidbrain0.09
0.11
ErasMYMedulla0.39
0.54
ErasOLFOlfactory bulb0.69
1.96
ErasPPons0.15
0.17
ErasPALPallidum0.06
0.05
ErasRHPRetrohippocampal region0.03
0
ErassAMYStriatum-like amygdalar nuclei0.06
0
ErasSTRStriatum0.03
0.03
ErasSTRdStriatum dorsal region0.03
0.03
ErasSTRvStriatum ventral region0.06
0.05
ErasTHThalamus0.04
0.02
Peptide Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018