AutismKB 2.0

Annotation Detail for HRH1


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Basic Information Top
Gene Symbol:HRH1 ( H1-R,hisH1 )
Gene Full Name: histamine receptor H1
Band: 3p25.3
Quick LinksEntrez ID:3269; OMIM: 600167; Uniprot ID:HRH1_HUMAN; ENSEMBL ID: ENSG00000196639; HGNC ID: 5182
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult17 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor2 / 2638457
glioma3 / 10688328
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal29 / 33603078
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain11 / 11009899
cervix2 / 4817141
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus1 / 2020949
eye0 / 2110540 
heart1 / 8962611
intestine5 / 23447221
kidney3 / 21177714
larynx0 / 241450 
liver5 / 20774324
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve1 / 1576863
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach4 / 9661941
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205580_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.35
Adipocyte5.1
AdrenalCortex5.6
Adrenalgland4.55
Amygdala5.45
Appendix5.35
AtrioventricularNode6
BDCA4+_DentriticCells5.55
Bonemarrow5.3
BronchialEpithelialCells5.1
CD105+_Endothelial5.05
CD14+_Monocytes5.55
CD19+_BCells(neg._sel.)5.5
CD33+_Myeloid6.55
CD34+6.65
CD4+_Tcells5.65
CD56+_NKCells6.05
CD71+_EarlyErythroid4.9
CD8+_Tcells4.95
CardiacMyocytes8.45
Caudatenucleus4.65
Cerebellum4.25
CerebellumPeduncles5.95
CiliaryGanglion7.6
CingulateCortex5.7
Colorectaladenocarcinoma5.2
DorsalRootGanglion4.35
FetalThyroid5.05
Fetalbrain5.05
Fetalliver4.55
Fetallung4.35
GlobusPallidus4.15
Heart6.75
Hypothalamus5.6
Kidney4.55
Leukemia_chronicMyelogenousK-5624.7
Leukemia_promyelocytic-HL-604.65
Leukemialymphoblastic(MOLT-4)4.25
Liver6.95
Lung5.75
Lymphnode4.45
Lymphoma_burkitts(Daudi)6.75
Lymphoma_burkitts(Raji)7.35
MedullaOblongata6.7
OccipitalLobe4.7
OlfactoryBulb4.15
Ovary3.7
Pancreas4.2
PancreaticIslet5.5
ParietalLobe5.55
Pituitary6.1
Placenta5.4
Pons5
PrefrontalCortex6.5
Prostate6.05
Salivarygland4.2
SkeletalMuscle6.5
Skin4.25
SmoothMuscle6.45
Spinalcord5.55
SubthalamicNucleus5.1
SuperiorCervicalGanglion9
TemporalLobe4.75
Testis4.4
TestisGermCell4.2
TestisIntersitial4.35
TestisLeydigCell5.15
TestisSeminiferousTubule4.5
Thalamus5.35
Thymus4.15
Thyroid6.35
Tongue5.45
Tonsil5
Trachea4.35
TrigeminalGanglion5.3
Uterus4.2
UterusCorpus4.85
WholeBlood5.65
Wholebrain4.25
colon5.2
pineal_day6.28
pineal_night6.16
retina6.275
small_intestine5.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_336_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.24 ± 0.91
Basal Forebrain3.64 ± 0.32
Basal Part of Pons3.74 ± 0.4
Cerebellar Cortex3.27 ± 0.53
Cerebellar Nuclei3.65 ± 0.81
Claustrum4.51 ± 0.8
Epithalamus3.3 ± 0.66
Frontal Lobe3.73 ± 0.58
Globus Pallidus4.01 ± 0.77
Hypothalamus3.58 ± 0.53
Insula3.58 ± 0.41
Limbic Lobe3.83 ± 0.6
Mesencephalon3.82 ± 0.68
Myelencephalon3.82 ± 0.62
Occipital Lobe3.59 ± 0.64
Parietal Lobe3.83 ± 0.61
Pontine Tegmentum3.72 ± 0.65
Striatum3.75 ± 0.6
Subthalamus3.81 ± 0.57
Temporal Lobe3.75 ± 0.55
Thalamus3.75 ± 0.59
White Matter4.01 ± 0.62
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hrh1CBCerebellum4.99
6.05
Hrh1CTXCerebral cortex9.37
7.29
Hrh1HIPHippocampal region1.86
2.26
Hrh1HPFHippocampal formation4.81
4.81
Hrh1HYHypothalamus2.42
2.51
Hrh1LSXLateral septal complex1.06
1.19
Hrh1MBMidbrain1.58
1.9
Hrh1MYMedulla4.63
5.69
Hrh1OLFOlfactory bulb5.43
4.59
Hrh1PPons4.49
4.69
Hrh1PALPallidum2.76
2.92
Hrh1RHPRetrohippocampal region9.51
8.13
Hrh1sAMYStriatum-like amygdalar nuclei8.23
6.22
Hrh1STRStriatum2.31
2.01
Hrh1STRdStriatum dorsal region1.65
1.62
Hrh1STRvStriatum ventral region1.87
1.36
Hrh1THThalamus0.98
1.17
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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