AutismKB 2.0

Annotation Detail for PRMT2


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Basic Information Top
Gene Symbol:PRMT2 ( HRMT1L1,MGC111373 )
Gene Full Name: protein arginine methyltransferase 2
Band: 21q22.3
Quick LinksEntrez ID:3275; OMIM: 601961; Uniprot ID:ANM2_HUMAN; ENSEMBL ID: ENSG00000160310; HGNC ID: 5186
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst7 / 62319112
fetus142 / 564012251
neonate4 / 31097128
infant2 / 2362084
juvenile7 / 55556125
adult272 / 1939121140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor23 / 94178244
cervical tumor2 / 3436658
chondrosarcoma17 / 82823205
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor12 / 119369100
germ cell tumor47 / 263845178
glioma12 / 106883112
head and neck tumor17 / 136302124
kidney tumor14 / 68959203
leukemia16 / 95842166
liver tumor4 / 9635941
lung tumor12 / 103127116
lymphoma12 / 71755167
non-neoplasia13 / 97250133
normal532 / 3360307158
ovarian tumor10 / 76682130
pancreatic tumor19 / 104616181
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer8 / 10268077
retinoblastoma7 / 46356151
skin tumor35 / 124949280
soft tissue/muscle tissue tumor17 / 125191135
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites6 / 40015149
bladder2 / 2975767
blood20 / 123478161
bone13 / 71655181
bone marrow5 / 48801102
brain192 / 1100989174
cervix5 / 48171103
connective tissue19 / 149255127
ear0 / 162120 
embryonic tissue30 / 215722139
esophagus1 / 2020949
eye42 / 211054199
heart27 / 89626301
intestine22 / 23447293
kidney37 / 211777174
larynx1 / 2414541
liver13 / 20774362
lung60 / 336974178
lymph8 / 44270180
lymph node10 / 91610109
mammary gland32 / 153271208
mouth4 / 6705259
muscle10 / 10771592
nerve5 / 15768317
ovary11 / 102051107
pancreas32 / 214812148
parathyroid3 / 20539146
pharynx10 / 41328241
pituitary gland0 / 165850 
placenta29 / 280825103
prostate22 / 189345116
salivary gland12 / 20155595
skin51 / 210574242
spleen3 / 5395255
stomach6 / 9661962
testis16 / 33044248
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord3 / 13680219
uterus31 / 232878133
vascular12 / 51780231
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202098_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts20.85
Adipocyte27.95
AdrenalCortex30.65
Adrenalgland21.85
Amygdala41.75
Appendix30.85
AtrioventricularNode21.35
BDCA4+_DentriticCells37.35
Bonemarrow32.1
BronchialEpithelialCells28.3
CD105+_Endothelial16.15
CD14+_Monocytes33.2
CD19+_BCells(neg._sel.)33.15
CD33+_Myeloid37.2
CD34+35.8
CD4+_Tcells297.2
CD56+_NKCells389.4
CD71+_EarlyErythroid6.55
CD8+_Tcells262
CardiacMyocytes35.55
Caudatenucleus27.5
Cerebellum27.8
CerebellumPeduncles51.9
CiliaryGanglion18.7
CingulateCortex36.45
Colorectaladenocarcinoma28.25
DorsalRootGanglion22.75
FetalThyroid30.55
Fetalbrain128.35
Fetalliver26.1
Fetallung27.65
GlobusPallidus22
Heart32.85
Hypothalamus105.8
Kidney24.15
Leukemia_chronicMyelogenousK-56225.55
Leukemia_promyelocytic-HL-6016.45
Leukemialymphoblastic(MOLT-4)20.9
Liver39.5
Lung36.75
Lymphnode28.15
Lymphoma_burkitts(Daudi)28
Lymphoma_burkitts(Raji)37
MedullaOblongata28.5
OccipitalLobe41.4
OlfactoryBulb48.15
Ovary21.25
Pancreas21.4
PancreaticIslet29.6
ParietalLobe32.4
Pituitary29.4
Placenta36.95
Pons32.25
PrefrontalCortex74.8
Prostate59.45
Salivarygland23.9
SkeletalMuscle30.45
Skin16.8
SmoothMuscle34.35
Spinalcord62.4
SubthalamicNucleus26.25
SuperiorCervicalGanglion33.7
TemporalLobe37.55
Testis25.85
TestisGermCell24.45
TestisIntersitial24.4
TestisLeydigCell30
TestisSeminiferousTubule26.1
Thalamus44.8
Thymus24.7
Thyroid38.8
Tongue28.3
Tonsil29.5
Trachea25.75
TrigeminalGanglion37.55
Uterus24.35
UterusCorpus25.4
WholeBlood91.65
Wholebrain101.4
colon30.8
pineal_day78.42
pineal_night55.38
retina71.75
small_intestine24.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P151498
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.98 ± 0.32
Basal Forebrain8.34 ± 0.32
Basal Part of Pons8.09 ± 0.26
Cerebellar Cortex7.68 ± 0.2
Cerebellar Nuclei8.23 ± 0.32
Claustrum8.37 ± 0.33
Epithalamus8.32 ± 0.23
Frontal Lobe8.14 ± 0.31
Globus Pallidus8.69 ± 0.21
Hypothalamus8.52 ± 0.23
Insula8.2 ± 0.23
Limbic Lobe7.85 ± 0.46
Mesencephalon8.14 ± 0.36
Myelencephalon8.04 ± 0.3
Occipital Lobe7.49 ± 0.37
Parietal Lobe7.9 ± 0.32
Pontine Tegmentum8.07 ± 0.26
Striatum7.73 ± 0.39
Subthalamus8.13 ± 0.11
Temporal Lobe8.09 ± 0.33
Thalamus7.96 ± 0.3
White Matter9.22 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prmt2CBCerebellum30.22
30.52
Prmt2CTXCerebral cortex53.27
44.64
Prmt2HIPHippocampal region71.63
87.11
Prmt2HPFHippocampal formation76.65
83.51
Prmt2HYHypothalamus100
100
Prmt2LSXLateral septal complex80.53
67.21
Prmt2MBMidbrain78.95
79.09
Prmt2MYMedulla59.9
69.1
Prmt2OLFOlfactory bulb70.85
54.4
Prmt2PPons69.66
78.13
Prmt2PALPallidum76.91
85.17
Prmt2RHPRetrohippocampal region86.12
76.01
Prmt2sAMYStriatum-like amygdalar nuclei99.67
92.48
Prmt2STRStriatum35.8
32.31
Prmt2STRdStriatum dorsal region15.63
15.4
Prmt2STRvStriatum ventral region40.08
33.71
Prmt2THThalamus47.09
48.37
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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