AutismKB 2.0

Annotation Detail for BIRC2


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Basic Information Top
Gene Symbol:BIRC2 ( API1,HIAP2,Hiap-2,MIHB,RNF48,c-IAP1,cIAP1 )
Gene Full Name: baculoviral IAP repeat-containing 2
Band: 11q22.2
Quick LinksEntrez ID:329; OMIM: 601712; Uniprot ID:BIRC2_HUMAN; ENSEMBL ID: ENSG00000110330; HGNC ID: 590
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus50 / 56401288
neonate2 / 3109764
infant1 / 2362042
juvenile8 / 55556143
adult166 / 193912185
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma4 / 17475228
breast (mammary gland) tumor9 / 9417895
cervical tumor3 / 3436687
chondrosarcoma8 / 8282396
colorectal tumor8 / 11424670
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor24 / 26384590
glioma4 / 10688337
head and neck tumor16 / 136302117
kidney tumor3 / 6895943
leukemia4 / 9584241
liver tumor11 / 96359114
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia10 / 97250102
normal315 / 336030793
ovarian tumor3 / 7668239
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor33 / 125191263
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites3 / 4001574
bladder6 / 29757201
blood11 / 12347889
bone3 / 7165541
bone marrow5 / 48801102
brain142 / 1100989128
cervix3 / 4817162
connective tissue44 / 149255294
ear3 / 16212185
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye8 / 21105437
heart1 / 8962611
intestine14 / 23447259
kidney12 / 21177756
larynx0 / 241450 
liver28 / 207743134
lung18 / 33697453
lymph0 / 442700 
lymph node11 / 91610120
mammary gland12 / 15327178
mouth14 / 67052208
muscle5 / 10771546
nerve2 / 15768126
ovary3 / 10205129
pancreas10 / 21481246
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta21 / 28082574
prostate3 / 18934515
salivary gland1 / 2015549
skin5 / 21057423
spleen6 / 53952111
stomach3 / 9661931
testis80 / 330442242
thymus30 / 81131369
thyroid4 / 4747384
tonsil0 / 169990 
trachea41 / 52413782
umbilical cord0 / 136800 
uterus28 / 232878120
vascular10 / 51780193
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202076_at
Cell line Expression level Expression bar
721_B_lymphoblasts271.75
Adipocyte66.05
AdrenalCortex66.35
Adrenalgland32.25
Amygdala136.25
Appendix48.95
AtrioventricularNode19.85
BDCA4+_DentriticCells511.65
Bonemarrow13.9
BronchialEpithelialCells148.8
CD105+_Endothelial291.05
CD14+_Monocytes494.65
CD19+_BCells(neg._sel.)560
CD33+_Myeloid699.35
CD34+442
CD4+_Tcells579.95
CD56+_NKCells793.3
CD71+_EarlyErythroid556.9
CD8+_Tcells558.3
CardiacMyocytes72.9
Caudatenucleus46.15
Cerebellum13.85
CerebellumPeduncles17.9
CiliaryGanglion27.85
CingulateCortex51.65
Colorectaladenocarcinoma128.95
DorsalRootGanglion20.8
FetalThyroid117.9
Fetalbrain321.6
Fetalliver91.05
Fetallung248.75
GlobusPallidus9.45
Heart16.7
Hypothalamus151.55
Kidney11.3
Leukemia_chronicMyelogenousK-56293.05
Leukemia_promyelocytic-HL-60134.05
Leukemialymphoblastic(MOLT-4)91.15
Liver14
Lung34.8
Lymphnode148.9
Lymphoma_burkitts(Daudi)69.35
Lymphoma_burkitts(Raji)113.55
MedullaOblongata36.75
OccipitalLobe58.15
OlfactoryBulb143.4
Ovary29.5
Pancreas77.1
PancreaticIslet131.5
ParietalLobe49.65
Pituitary138.95
Placenta30.45
Pons21.5
PrefrontalCortex121.3
Prostate117
Salivarygland94.6
SkeletalMuscle16
Skin37.1
SmoothMuscle136.95
Spinalcord115.35
SubthalamicNucleus18.45
SuperiorCervicalGanglion22.25
TemporalLobe15.05
Testis21.05
TestisGermCell181.8
TestisIntersitial59.85
TestisLeydigCell73.95
TestisSeminiferousTubule83.65
Thalamus72.95
Thymus68.5
Thyroid181.3
Tongue27.85
Tonsil79.6
Trachea91.25
TrigeminalGanglion24.8
Uterus209.15
UterusCorpus14.55
WholeBlood244.7
Wholebrain60.2
colon92.4
pineal_day202.62
pineal_night250.58
retina68.3
small_intestine47.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P115774
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.23 ± 0.2
Basal Forebrain8.09 ± 0.22
Basal Part of Pons8.16 ± 0.12
Cerebellar Cortex8.21 ± 0.19
Cerebellar Nuclei8.07 ± 0.2
Claustrum8.46 ± 0.27
Epithalamus8.32 ± 0.17
Frontal Lobe8.07 ± 0.2
Globus Pallidus8.33 ± 0.09
Hypothalamus8.09 ± 0.18
Insula8.12 ± 0.13
Limbic Lobe8.23 ± 0.27
Mesencephalon8.13 ± 0.23
Myelencephalon8.13 ± 0.25
Occipital Lobe8.33 ± 0.25
Parietal Lobe8.08 ± 0.21
Pontine Tegmentum8.11 ± 0.26
Striatum7.97 ± 0.22
Subthalamus8.1 ± 0.11
Temporal Lobe8.11 ± 0.2
Thalamus8.11 ± 0.2
White Matter8.85 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Birc2CBCerebellum24.56
52.18
Birc2CTXCerebral cortex50.96
36.65
Birc2HIPHippocampal region31.45
31.86
Birc2HPFHippocampal formation36.84
33.15
Birc2HYHypothalamus31.06
23.27
Birc2LSXLateral septal complex30.95
22.26
Birc2MBMidbrain23.7
19.89
Birc2MYMedulla34.29
34.98
Birc2OLFOlfactory bulb40.29
31.2
Birc2PPons29.2
27.64
Birc2PALPallidum30.83
26.73
Birc2RHPRetrohippocampal region47.62
36.26
Birc2sAMYStriatum-like amygdalar nuclei30.26
20.49
Birc2STRStriatum27.65
19.37
Birc2STRdStriatum dorsal region27
19.4
Birc2STRvStriatum ventral region28.48
18.19
Birc2THThalamus23.61
17.95
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00503724 16 426 441 TVNDIVSALLNAEDEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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