AutismKB 2.0

Annotation Detail for DNAJB1


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Basic Information Top
Gene Symbol:DNAJB1 ( HSPF1,Hdj1,Hsp40,RSPH16B,Sis1 )
Gene Full Name: DnaJ (Hsp40) homolog, subfamily B, member 1
Band: 19p13.12
Quick LinksEntrez ID:3337; OMIM: 604572; Uniprot ID:DNJB1_HUMAN; ENSEMBL ID: ENSG00000132002; HGNC ID: 5270
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst6 / 6231996
fetus77 / 564012136
neonate10 / 31097321
infant5 / 23620211
juvenile24 / 55556431
adult403 / 1939121207
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor24 / 94178254
cervical tumor8 / 34366232
chondrosarcoma11 / 82823132
colorectal tumor17 / 114246148
esophageal tumor5 / 17290289
gastrointestinal tumor25 / 119369209
germ cell tumor75 / 263845284
glioma22 / 106883205
head and neck tumor9 / 13630266
kidney tumor19 / 68959275
leukemia11 / 95842114
liver tumor18 / 96359186
lung tumor19 / 103127184
lymphoma5 / 7175569
non-neoplasia16 / 97250164
normal759 / 3360307225
ovarian tumor14 / 76682182
pancreatic tumor25 / 104616238
primitive neuroectodermal tumor of the CNS28 / 125680222
prostate cancer7 / 10268068
retinoblastoma9 / 46356194
skin tumor19 / 124949152
soft tissue/muscle tissue tumor36 / 125191287
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue13 / 13106991
adrenal gland6 / 33197180
ascites14 / 40015349
bladder6 / 29757201
blood15 / 123478121
bone9 / 71655125
bone marrow9 / 48801184
brain203 / 1100989184
cervix8 / 48171166
connective tissue13 / 14925587
ear1 / 1621261
embryonic tissue26 / 215722120
esophagus5 / 20209247
eye35 / 211054165
heart20 / 89626223
intestine52 / 234472221
kidney41 / 211777193
larynx0 / 241450 
liver33 / 207743158
lung86 / 336974255
lymph3 / 4427067
lymph node4 / 9161043
mammary gland54 / 153271352
mouth6 / 6705289
muscle15 / 107715139
nerve11 / 15768697
ovary16 / 102051156
pancreas41 / 214812190
parathyroid3 / 20539146
pharynx2 / 4132848
pituitary gland5 / 16585301
placenta45 / 280825160
prostate40 / 189345211
salivary gland2 / 2015599
skin46 / 210574218
spleen32 / 53952593
stomach8 / 9661982
testis172 / 330442520
thymus15 / 81131184
thyroid5 / 47473105
tonsil1 / 1699958
trachea12 / 52413228
umbilical cord0 / 136800 
uterus69 / 232878296
vascular10 / 51780193
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200664_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts113.65
Adipocyte44.7
AdrenalCortex48.25
Adrenalgland82.55
Amygdala55.3
Appendix37.1
AtrioventricularNode291.85
BDCA4+_DentriticCells130.7
Bonemarrow205.2
BronchialEpithelialCells132
CD105+_Endothelial92.7
CD14+_Monocytes69
CD19+_BCells(neg._sel.)76.6
CD33+_Myeloid131.8
CD34+78.75
CD4+_Tcells1212.05
CD56+_NKCells281.4
CD71+_EarlyErythroid234.15
CD8+_Tcells876.05
CardiacMyocytes35.25
Caudatenucleus37.6
Cerebellum106.3
CerebellumPeduncles47.65
CiliaryGanglion35.25
CingulateCortex37.8
Colorectaladenocarcinoma147
DorsalRootGanglion27.6
FetalThyroid36
Fetalbrain51.7
Fetalliver42.2
Fetallung121.55
GlobusPallidus30.4
Heart54.75
Hypothalamus49
Kidney46
Leukemia_chronicMyelogenousK-562280
Leukemia_promyelocytic-HL-6040.2
Leukemialymphoblastic(MOLT-4)33.25
Liver90.05
Lung309.5
Lymphnode135.55
Lymphoma_burkitts(Daudi)43.7
Lymphoma_burkitts(Raji)55.5
MedullaOblongata33.75
OccipitalLobe42.5
OlfactoryBulb240.75
Ovary22.65
Pancreas161
PancreaticIslet67.9
ParietalLobe39.65
Pituitary79.4
Placenta197
Pons33.55
PrefrontalCortex30.6
Prostate127.9
Salivarygland20.15
SkeletalMuscle45.9
Skin30.75
SmoothMuscle48.85
Spinalcord83.75
SubthalamicNucleus33.6
SuperiorCervicalGanglion39.05
TemporalLobe39.1
Testis423.9
TestisGermCell312.85
TestisIntersitial579.5
TestisLeydigCell294.4
TestisSeminiferousTubule192.6
Thalamus31.6
Thymus273
Thyroid58.95
Tongue44.95
Tonsil52.75
Trachea183.2
TrigeminalGanglion34.5
Uterus52.35
UterusCorpus38.7
WholeBlood47.4
Wholebrain84.65
colon43.95
pineal_day193.06
pineal_night137.68
retina89.45
small_intestine33.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13045_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.28 ± 0.31
Basal Forebrain6.42 ± 0.37
Basal Part of Pons6.6 ± 0.35
Cerebellar Cortex6.22 ± 0.19
Cerebellar Nuclei7.15 ± 0.25
Claustrum6.7 ± 0.49
Epithalamus6.98 ± 0.39
Frontal Lobe6.44 ± 0.3
Globus Pallidus7.22 ± 0.17
Hypothalamus6.55 ± 0.53
Insula6.52 ± 0.34
Limbic Lobe6.49 ± 0.35
Mesencephalon6.58 ± 0.31
Myelencephalon6.5 ± 0.35
Occipital Lobe6.41 ± 0.37
Parietal Lobe6.42 ± 0.37
Pontine Tegmentum6.49 ± 0.36
Striatum6.8 ± 0.38
Subthalamus6.64 ± 0.2
Temporal Lobe6.42 ± 0.29
Thalamus6.62 ± 0.24
White Matter7.76 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dnajb1CBCerebellum31.52
53.03
Dnajb1CTXCerebral cortex96.89
91.91
Dnajb1HIPHippocampal region52.73
76.82
Dnajb1HPFHippocampal formation73.11
78.5
Dnajb1HYHypothalamus60.8
56.04
Dnajb1LSXLateral septal complex66.66
66.83
Dnajb1MBMidbrain61.84
61.46
Dnajb1MYMedulla60.93
65.77
Dnajb1OLFOlfactory bulb77.91
75.14
Dnajb1PPons59.49
65.34
Dnajb1PALPallidum65.36
68.23
Dnajb1RHPRetrohippocampal region89.7
84
Dnajb1sAMYStriatum-like amygdalar nuclei64.35
53.61
Dnajb1STRStriatum59.27
47.85
Dnajb1STRdStriatum dorsal region56.77
44.94
Dnajb1STRvStriatum ventral region59.1
46.62
Dnajb1THThalamus60.15
56.52
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DNJB1_HUMAN_1 12 1 12 GKDYYQTLGLAR PRIDE
DNJB1_HUMAN_2 12 2 13 GKDYYQTLGLAR PRIDE
DNJB1_HUMAN_249 10 249 258 DGSDVIYPAR PRIDE
DNJB1_HUMAN_66 7 66 72 YGEEGLK PRIDE
PAp00008605 12 170 181 VSLEEIYSGCTK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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