AutismKB 2.0

Annotation Detail for PPM1J


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Basic Information Top
Gene Symbol:PPM1J ( DKFZp434P1514,FLJ35951,MGC19531,MGC90149,PP2CZ,PP2Czeta,PPP2CZ )
Gene Full Name: protein phosphatase, Mg2+/Mn2+ dependent, 1J
Band: 1p13.2
Quick LinksEntrez ID:333926; OMIM: 609957; Uniprot ID:PPM1J_HUMAN; ENSEMBL ID: ENSG00000155367; HGNC ID: 20785
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal48 / 336030714
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain23 / 110098920
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine2 / 2344728
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary4 / 10205139
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta5 / 28082517
prostate2 / 18934510
salivary gland1 / 2015549
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis12 / 33044236
thymus1 / 8113112
thyroid1 / 4747321
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8018_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.99 ± 0.5
Basal Forebrain4.35 ± 0.5
Basal Part of Pons5.15 ± 0.38
Cerebellar Cortex5.43 ± 0.35
Cerebellar Nuclei4.46 ± 0.71
Claustrum5.4 ± 0.52
Epithalamus5.54 ± 0.88
Frontal Lobe4.89 ± 0.53
Globus Pallidus4.05 ± 0.4
Hypothalamus4.45 ± 0.61
Insula5.19 ± 0.39
Limbic Lobe4.74 ± 0.53
Mesencephalon4.84 ± 0.67
Myelencephalon4.92 ± 0.63
Occipital Lobe4.46 ± 0.55
Parietal Lobe4.97 ± 0.56
Pontine Tegmentum4.76 ± 0.62
Striatum3.88 ± 0.59
Subthalamus4.7 ± 0.23
Temporal Lobe5.11 ± 0.46
Thalamus5.27 ± 0.55
White Matter3.62 ± 0.33
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018