AutismKB 2.0

Annotation Detail for NDST1


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Basic Information Top
Gene Symbol:NDST1 ( HSST,NST1 )
Gene Full Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
Band: 5q33.1
Quick LinksEntrez ID:3340; OMIM: 600853; Uniprot ID:NDST1_HUMAN; ENSEMBL ID: ENSG00000070614; HGNC ID: 7680
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body15 / 70761211
blastocyst4 / 6231964
fetus14 / 56401224
neonate0 / 310970 
infant3 / 23620127
juvenile2 / 5555635
adult111 / 193912157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor7 / 9417874
cervical tumor2 / 3436658
chondrosarcoma14 / 82823169
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor9 / 26384534
glioma14 / 106883130
head and neck tumor15 / 136302110
kidney tumor8 / 68959116
leukemia10 / 95842104
liver tumor4 / 9635941
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal136 / 336030740
ovarian tumor12 / 76682156
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer5 / 10268048
retinoblastoma2 / 4635643
skin tumor9 / 12494972
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites0 / 400150 
bladder2 / 2975767
blood8 / 12347864
bone8 / 71655111
bone marrow2 / 4880140
brain61 / 110098955
cervix2 / 4817141
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue22 / 215722101
esophagus0 / 202090 
eye11 / 21105452
heart0 / 896260 
intestine17 / 23447272
kidney13 / 21177761
larynx3 / 24145124
liver5 / 20774324
lung13 / 33697438
lymph0 / 442700 
lymph node1 / 9161010
mammary gland10 / 15327165
mouth2 / 6705229
muscle2 / 10771518
nerve2 / 15768126
ovary13 / 102051127
pancreas6 / 21481227
parathyroid2 / 2053997
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta3 / 28082510
prostate8 / 18934542
salivary gland0 / 201550 
skin21 / 21057499
spleen2 / 5395237
stomach0 / 966190 
testis9 / 33044227
thymus0 / 811310 
thyroid8 / 47473168
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus14 / 23287860
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202607_at
Cell line Expression level Expression bar
721_B_lymphoblasts56
Adipocyte123.5
AdrenalCortex82.95
Adrenalgland95.4
Amygdala66.6
Appendix60.4
AtrioventricularNode63.25
BDCA4+_DentriticCells27.15
Bonemarrow63.4
BronchialEpithelialCells74.95
CD105+_Endothelial35
CD14+_Monocytes45.45
CD19+_BCells(neg._sel.)16
CD33+_Myeloid51.45
CD34+27.95
CD4+_Tcells17.65
CD56+_NKCells14.45
CD71+_EarlyErythroid54.9
CD8+_Tcells16.25
CardiacMyocytes66.9
Caudatenucleus83.55
Cerebellum53
CerebellumPeduncles153
CiliaryGanglion38.6
CingulateCortex120.2
Colorectaladenocarcinoma21.4
DorsalRootGanglion86.9
FetalThyroid78.9
Fetalbrain64.95
Fetalliver67.35
Fetallung46.25
GlobusPallidus94.3
Heart82.35
Hypothalamus154.55
Kidney60.7
Leukemia_chronicMyelogenousK-56242
Leukemia_promyelocytic-HL-6038.05
Leukemialymphoblastic(MOLT-4)35.65
Liver78.95
Lung133.5
Lymphnode39.7
Lymphoma_burkitts(Daudi)78.45
Lymphoma_burkitts(Raji)58.85
MedullaOblongata111.15
OccipitalLobe86.35
OlfactoryBulb68.25
Ovary66.2
Pancreas44.35
PancreaticIslet62.9
ParietalLobe102.7
Pituitary68.7
Placenta56.25
Pons104.5
PrefrontalCortex76.05
Prostate69.7
Salivarygland58.2
SkeletalMuscle95.3
Skin40.2
SmoothMuscle116.4
Spinalcord116.8
SubthalamicNucleus148.2
SuperiorCervicalGanglion103.1
TemporalLobe95.85
Testis51.05
TestisGermCell60.2
TestisIntersitial46.05
TestisLeydigCell87.7
TestisSeminiferousTubule57.15
Thalamus165.55
Thymus26.7
Thyroid48.2
Tongue101.05
Tonsil53.35
Trachea55.65
TrigeminalGanglion113.55
Uterus28.75
UterusCorpus62.25
WholeBlood55.4
Wholebrain71.1
colon35.8
pineal_day36.32
pineal_night37.04
retina90.025
small_intestine53.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15033_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.43 ± 0.66
Basal Forebrain5.32 ± 0.29
Basal Part of Pons4.65 ± 0.62
Cerebellar Cortex4.59 ± 0.5
Cerebellar Nuclei5.63 ± 0.58
Claustrum5.91 ± 0.95
Epithalamus4.41 ± 0.51
Frontal Lobe4.96 ± 0.71
Globus Pallidus6.1 ± 0.35
Hypothalamus4.53 ± 0.44
Insula4.71 ± 0.7
Limbic Lobe5.34 ± 0.73
Mesencephalon5.34 ± 0.6
Myelencephalon5.26 ± 0.74
Occipital Lobe5.49 ± 0.61
Parietal Lobe5.23 ± 0.7
Pontine Tegmentum5.27 ± 0.6
Striatum5.64 ± 0.66
Subthalamus4.85 ± 0.26
Temporal Lobe4.99 ± 0.58
Thalamus5.62 ± 0.46
White Matter6.63 ± 0.71
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ndst1CBCerebellum21.21
37.42
Ndst1CTXCerebral cortex52.12
42.84
Ndst1HIPHippocampal region29.53
45.23
Ndst1HPFHippocampal formation37.46
42.75
Ndst1HYHypothalamus10.04
7.38
Ndst1LSXLateral septal complex4.95
3.19
Ndst1MBMidbrain7.59
6.4
Ndst1MYMedulla13.51
12.64
Ndst1OLFOlfactory bulb29.16
21.75
Ndst1PPons10.06
8.69
Ndst1PALPallidum16.89
15.54
Ndst1RHPRetrohippocampal region52.53
41.93
Ndst1sAMYStriatum-like amygdalar nuclei18.66
12.78
Ndst1STRStriatum35.49
25.64
Ndst1STRdStriatum dorsal region47.77
35.56
Ndst1STRvStriatum ventral region16.72
10.46
Ndst1THThalamus26.51
22.81
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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