AutismKB 2.0

Annotation Detail for ICAM1


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Basic Information Top
Gene Symbol:ICAM1 ( BB2,CD54,P3.58 )
Gene Full Name: intercellular adhesion molecule 1
Band: 19p13.2
Quick LinksEntrez ID:3383; OMIM: 147840; Uniprot ID:ICAM1_HUMAN; ENSEMBL ID: ENSG00000090339; HGNC ID: 5344
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus7 / 56401212
neonate8 / 31097257
infant0 / 236200 
juvenile1 / 5555617
adult183 / 193912194
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma3 / 17475171
breast (mammary gland) tumor17 / 94178180
cervical tumor1 / 3436629
chondrosarcoma7 / 8282384
colorectal tumor6 / 11424652
esophageal tumor4 / 17290231
gastrointestinal tumor6 / 11936950
germ cell tumor40 / 263845151
glioma3 / 10688328
head and neck tumor18 / 136302132
kidney tumor6 / 6895987
leukemia9 / 9584293
liver tumor11 / 96359114
lung tumor7 / 10312767
lymphoma5 / 7175569
non-neoplasia23 / 97250236
normal337 / 3360307100
ovarian tumor1 / 7668213
pancreatic tumor14 / 104616133
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor12 / 12494996
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland2 / 3319760
ascites0 / 400150 
bladder2 / 2975767
blood16 / 123478129
bone0 / 716550 
bone marrow4 / 4880181
brain31 / 110098928
cervix1 / 4817120
connective tissue33 / 149255221
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus4 / 20209197
eye5 / 21105423
heart2 / 8962622
intestine11 / 23447246
kidney15 / 21177770
larynx0 / 241450 
liver19 / 20774391
lung169 / 336974501
lymph1 / 4427022
lymph node4 / 9161043
mammary gland21 / 153271137
mouth13 / 67052193
muscle11 / 107715102
nerve1 / 1576863
ovary1 / 1020519
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta20 / 28082571
prostate3 / 18934515
salivary gland0 / 201550 
skin12 / 21057456
spleen33 / 53952611
stomach8 / 9661982
testis17 / 33044251
thymus24 / 81131295
thyroid7 / 47473147
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord0 / 136800 
uterus12 / 23287851
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215485_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts224.05
Adipocyte322.9
AdrenalCortex382.1
Adrenalgland359.1
Amygdala271.7
Appendix266
AtrioventricularNode466.3
BDCA4+_DentriticCells162.6
Bonemarrow395.35
BronchialEpithelialCells252.1
CD105+_Endothelial210.25
CD14+_Monocytes224.6
CD19+_BCells(neg._sel.)137
CD33+_Myeloid263
CD34+158.6
CD4+_Tcells178.1
CD56+_NKCells178.9
CD71+_EarlyErythroid264.1
CD8+_Tcells105.1
CardiacMyocytes369.4
Caudatenucleus525
Cerebellum434.3
CerebellumPeduncles397.45
CiliaryGanglion432.5
CingulateCortex382.9
Colorectaladenocarcinoma299.05
DorsalRootGanglion220.3
FetalThyroid274.35
Fetalbrain323.75
Fetalliver329.7
Fetallung599.25
GlobusPallidus233.95
Heart386.3
Hypothalamus308.15
Kidney386.25
Leukemia_chronicMyelogenousK-562289.35
Leukemia_promyelocytic-HL-60262.3
Leukemialymphoblastic(MOLT-4)229
Liver555.45
Lung352.55
Lymphnode312.15
Lymphoma_burkitts(Daudi)468.55
Lymphoma_burkitts(Raji)435.9
MedullaOblongata245.95
OccipitalLobe254.2
OlfactoryBulb223.35
Ovary211.15
Pancreas322.1
PancreaticIslet572.6
ParietalLobe445.95
Pituitary504.75
Placenta274.8
Pons352.2
PrefrontalCortex349.75
Prostate331.4
Salivarygland225.45
SkeletalMuscle539.65
Skin272.65
SmoothMuscle467.6
Spinalcord323.35
SubthalamicNucleus416.1
SuperiorCervicalGanglion336.6
TemporalLobe257.7
Testis269.15
TestisGermCell214.55
TestisIntersitial213.35
TestisLeydigCell265
TestisSeminiferousTubule287.95
Thalamus340.85
Thymus203.8
Thyroid311.3
Tongue313.95
Tonsil319.2
Trachea282.2
TrigeminalGanglion284.6
Uterus217.7
UterusCorpus251.1
WholeBlood291.05
Wholebrain272.6
colon252.75
pineal_day186.16
pineal_night137.84
retina331.625
small_intestine251.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16891_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.94 ± 1
Basal Forebrain1.45 ± 0.18
Basal Part of Pons1.19 ± 0.33
Cerebellar Cortex1.34 ± 0.73
Cerebellar Nuclei1.74 ± 0.69
Claustrum2.33 ± 0.86
Epithalamus1.26 ± 0.73
Frontal Lobe1.35 ± 0.59
Globus Pallidus2.07 ± 0.35
Hypothalamus1.58 ± 0.68
Insula1.51 ± 0.85
Limbic Lobe1.48 ± 0.59
Mesencephalon1.65 ± 0.67
Myelencephalon1.52 ± 0.66
Occipital Lobe1.52 ± 0.57
Parietal Lobe1.49 ± 0.71
Pontine Tegmentum1.53 ± 0.68
Striatum1.7 ± 0.5
Subthalamus1.6 ± 0.6
Temporal Lobe1.36 ± 0.58
Thalamus1.48 ± 0.6
White Matter2.28 ± 0.73
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ICAM1_HUMAN_0 0 0 0 ASVSVTAEDEGTQR PRIDE
PAp00000715 14 274 287 ASVSVTAEDEGTQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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