AutismKB 2.0

Annotation Detail for CCDC137


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Basic Information Top
Gene Symbol:CCDC137 ( MGC16597 )
Gene Full Name: coiled-coil domain containing 137
Band: 17q25.3
Quick LinksEntrez ID:339230; OMIM: NA; Uniprot ID:CC137_HUMAN; ENSEMBL ID: ENSG00000185298; HGNC ID: 33451
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst4 / 6231964
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor13 / 26384549
glioma9 / 10688384
head and neck tumor0 / 1363020 
kidney tumor6 / 6895987
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal53 / 336030715
ovarian tumor4 / 7668252
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer3 / 10268029
retinoblastoma4 / 4635686
skin tumor13 / 124949104
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder1 / 2975733
blood7 / 12347856
bone2 / 7165527
bone marrow0 / 488010 
brain19 / 110098917
cervix4 / 4817183
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye8 / 21105437
heart1 / 8962611
intestine2 / 2344728
kidney8 / 21177737
larynx0 / 241450 
liver1 / 2077434
lung6 / 33697417
lymph0 / 442700 
lymph node2 / 9161021
mammary gland5 / 15327132
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary7 / 10205168
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate4 / 18934521
salivary gland1 / 2015549
skin14 / 21057466
spleen0 / 539520 
stomach1 / 9661910
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P230176
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.32 ± 0.49
Basal Forebrain7.53 ± 0.17
Basal Part of Pons8.01 ± 0.18
Cerebellar Cortex7.85 ± 0.23
Cerebellar Nuclei7.66 ± 0.35
Claustrum7.62 ± 0.36
Epithalamus7.77 ± 0.17
Frontal Lobe7.75 ± 0.27
Globus Pallidus7.64 ± 0.22
Hypothalamus7.71 ± 0.25
Insula7.72 ± 0.21
Limbic Lobe7.64 ± 0.28
Mesencephalon7.62 ± 0.23
Myelencephalon7.64 ± 0.35
Occipital Lobe7.46 ± 0.32
Parietal Lobe7.72 ± 0.28
Pontine Tegmentum7.54 ± 0.27
Striatum7.36 ± 0.31
Subthalamus7.83 ± 0.14
Temporal Lobe7.73 ± 0.29
Thalamus7.64 ± 0.24
White Matter7.74 ± 0.26
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018