AutismKB 2.0

Annotation Detail for SPOPL


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Basic Information Top
Gene Symbol:SPOPL ( FLJ53775 )
Gene Full Name: speckle-type POZ protein-like
Band: 2q22.1
Quick LinksEntrez ID:339745; OMIM: NA; Uniprot ID:SPOPL_HUMAN; ENSEMBL ID: ENSG00000144228; HGNC ID: 27934
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult69 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor8 / 26384530
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor4 / 9635941
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia1 / 9725010
normal118 / 336030735
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites1 / 4001524
bladder2 / 2975767
blood2 / 12347816
bone0 / 716550 
bone marrow2 / 4880140
brain29 / 110098926
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye1 / 2110544
heart3 / 8962633
intestine9 / 23447238
kidney4 / 21177718
larynx0 / 241450 
liver6 / 20774328
lung11 / 33697432
lymph0 / 442700 
lymph node23 / 91610251
mammary gland12 / 15327178
mouth1 / 6705214
muscle6 / 10771555
nerve0 / 157680 
ovary4 / 10205139
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate5 / 18934526
salivary gland1 / 2015549
skin3 / 21057414
spleen1 / 5395218
stomach3 / 9661931
testis8 / 33044224
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P79681
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.28 ± 0.22
Basal Forebrain7.39 ± 0.19
Basal Part of Pons7.46 ± 0.25
Cerebellar Cortex7.26 ± 0.17
Cerebellar Nuclei7.56 ± 0.29
Claustrum7.21 ± 0.3
Epithalamus7.22 ± 0.36
Frontal Lobe7.32 ± 0.28
Globus Pallidus7.89 ± 0.2
Hypothalamus7.37 ± 0.22
Insula7.24 ± 0.16
Limbic Lobe7.26 ± 0.34
Mesencephalon7.38 ± 0.26
Myelencephalon7.26 ± 0.31
Occipital Lobe7.31 ± 0.3
Parietal Lobe7.34 ± 0.28
Pontine Tegmentum7.28 ± 0.31
Striatum7.15 ± 0.27
Subthalamus7.33 ± 0.14
Temporal Lobe7.23 ± 0.27
Thalamus7.19 ± 0.33
White Matter8.56 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
4921517N04RikCBCerebellum1.02
1.38
4921517N04RikCTXCerebral cortex0.87
1.38
4921517N04RikHIPHippocampal region1.33
1.42
4921517N04RikHPFHippocampal formation1.02
1.08
4921517N04RikHYHypothalamus0.16
0.16
4921517N04RikLSXLateral septal complex0.22
0.31
4921517N04RikMBMidbrain0.83
1.17
4921517N04RikMYMedulla0.78
1.01
4921517N04RikOLFOlfactory bulb1.22
1.09
4921517N04RikPPons0.38
0.57
4921517N04RikPALPallidum0.27
0.56
4921517N04RikRHPRetrohippocampal region0.44
0.59
4921517N04RiksAMYStriatum-like amygdalar nuclei0.16
0.26
4921517N04RikSTRStriatum0.67
0.87
4921517N04RikSTRdStriatum dorsal region1.06
1.41
4921517N04RikSTRvStriatum ventral region0.14
0.09
4921517N04RikTHThalamus0.36
0.33
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018