AutismKB 2.0

Annotation Detail for ID4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ID4 ( IDB4,bHLHb27 )
Gene Full Name: inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
Band: 6p22.3
Quick LinksEntrez ID:3400; OMIM: 600581; Uniprot ID:ID4_HUMAN; ENSEMBL ID: ENSG00000172201; HGNC ID: 5363
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus44 / 56401278
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult97 / 193912150
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor4 / 26384515
glioma29 / 106883271
head and neck tumor13 / 13630295
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal184 / 336030754
ovarian tumor27 / 76682352
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone7 / 7165597
bone marrow2 / 4880140
brain84 / 110098976
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue21 / 21572297
esophagus0 / 202090 
eye14 / 21105466
heart3 / 8962633
intestine4 / 23447217
kidney10 / 21177747
larynx0 / 241450 
liver3 / 20774314
lung68 / 336974201
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle2 / 10771518
nerve2 / 15768126
ovary29 / 102051284
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate9 / 18934547
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach2 / 9661920
testis15 / 33044245
thymus0 / 811310 
thyroid16 / 47473337
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209291_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.55
Adipocyte15.95
AdrenalCortex7.5
Adrenalgland13.05
Amygdala337.05
Appendix15.85
AtrioventricularNode15.35
BDCA4+_DentriticCells6.15
Bonemarrow11.6
BronchialEpithelialCells6.2
CD105+_Endothelial15.2
CD14+_Monocytes6.25
CD19+_BCells(neg._sel.)6.1
CD33+_Myeloid7.25
CD34+8.15
CD4+_Tcells5.9
CD56+_NKCells6.65
CD71+_EarlyErythroid5.85
CD8+_Tcells5.35
CardiacMyocytes11.65
Caudatenucleus121.35
Cerebellum59.7
CerebellumPeduncles28.7
CiliaryGanglion12.5
CingulateCortex18.35
Colorectaladenocarcinoma6
DorsalRootGanglion12.25
FetalThyroid1006.05
Fetalbrain259.2
Fetalliver7.4
Fetallung51.75
GlobusPallidus28.9
Heart13.9
Hypothalamus338.25
Kidney24.9
Leukemia_chronicMyelogenousK-5625.2
Leukemia_promyelocytic-HL-605.35
Leukemialymphoblastic(MOLT-4)6.4
Liver9.15
Lung120.65
Lymphnode38.85
Lymphoma_burkitts(Daudi)10.45
Lymphoma_burkitts(Raji)9.15
MedullaOblongata24.6
OccipitalLobe47.65
OlfactoryBulb65.95
Ovary87.15
Pancreas19.55
PancreaticIslet91.5
ParietalLobe14.5
Pituitary253.9
Placenta96.3
Pons21.6
PrefrontalCortex210.15
Prostate257.2
Salivarygland14.75
SkeletalMuscle11.95
Skin81.9
SmoothMuscle8.95
Spinalcord122.3
SubthalamicNucleus26.6
SuperiorCervicalGanglion20.8
TemporalLobe15.9
Testis94.7
TestisGermCell163.15
TestisIntersitial15.1
TestisLeydigCell40.1
TestisSeminiferousTubule45.55
Thalamus62.55
Thymus10.4
Thyroid4446.6
Tongue19
Tonsil12.4
Trachea129.95
TrigeminalGanglion18.85
Uterus328.55
UterusCorpus24.15
WholeBlood6.25
Wholebrain122.45
colon51.1
pineal_day159.68
pineal_night150.82
retina311.175
small_intestine84.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8918_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.74 ± 0.38
Basal Forebrain10.12 ± 0.23
Basal Part of Pons9.03 ± 0.28
Cerebellar Cortex9.46 ± 0.26
Cerebellar Nuclei8.86 ± 0.45
Claustrum9.55 ± 0.47
Epithalamus10.81 ± 0.46
Frontal Lobe9.59 ± 0.43
Globus Pallidus10.59 ± 0.24
Hypothalamus10.07 ± 0.3
Insula9.54 ± 0.39
Limbic Lobe9.47 ± 0.52
Mesencephalon9.9 ± 0.56
Myelencephalon9.77 ± 0.5
Occipital Lobe9.98 ± 0.53
Parietal Lobe9.7 ± 0.46
Pontine Tegmentum9.79 ± 0.33
Striatum9.82 ± 0.63
Subthalamus8.85 ± 0.46
Temporal Lobe9.75 ± 0.32
Thalamus9.95 ± 0.37
White Matter8.51 ± 0.53
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Id4CBCerebellum26.15
95.53
Id4CTXCerebral cortex24.85
17.9
Id4HIPHippocampal region25
29.06
Id4HPFHippocampal formation27.51
27.97
Id4HYHypothalamus25.21
22.73
Id4LSXLateral septal complex89.79
100
Id4MBMidbrain25.23
25.13
Id4MYMedulla21.19
24.73
Id4OLFOlfactory bulb40.57
33.7
Id4PPons16.92
16.99
Id4PALPallidum33.63
34.22
Id4RHPRetrohippocampal region30.71
25.52
Id4sAMYStriatum-like amygdalar nuclei43.78
39.33
Id4STRStriatum90.84
96.99
Id4STRdStriatum dorsal region94.25
100
Id4STRvStriatum ventral region94.28
94.67
Id4THThalamus56.24
59.55
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00497265 21 117 137 QPPPPAPPHHPAGTCPAAPPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved