AutismKB 2.0

Annotation Detail for APOC1


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Basic Information Top
Gene Symbol:APOC1 ( - )
Gene Full Name: apolipoprotein C-I
Band: 19q13.32
Quick LinksEntrez ID:341; OMIM: 107710; Uniprot ID:APOC1_HUMAN; ENSEMBL ID: ENSG00000130208; HGNC ID: 607
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus41 / 56401272
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult82 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor8 / 26384530
glioma9 / 10688384
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor20 / 96359207
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal150 / 336030744
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland8 / 33197240
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow2 / 4880140
brain20 / 110098918
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye3 / 21105414
heart5 / 8962655
intestine4 / 23447217
kidney10 / 21177747
larynx0 / 241450 
liver66 / 207743317
lung16 / 33697447
lymph0 / 442700 
lymph node1 / 9161010
mammary gland6 / 15327139
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta5 / 28082517
prostate1 / 1893455
salivary gland1 / 2015549
skin0 / 2105740 
spleen1 / 5395218
stomach1 / 9661910
testis2 / 3304426
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213553_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.75
Adipocyte119.3
AdrenalCortex934.85
Adrenalgland342.1
Amygdala48.7
Appendix37.8
AtrioventricularNode66.05
BDCA4+_DentriticCells9.3
Bonemarrow43.4
BronchialEpithelialCells20.65
CD105+_Endothelial43.75
CD14+_Monocytes10
CD19+_BCells(neg._sel.)7.25
CD33+_Myeloid16.6
CD34+49.45
CD4+_Tcells24.8
CD56+_NKCells8.4
CD71+_EarlyErythroid22.25
CD8+_Tcells25.7
CardiacMyocytes15.45
Caudatenucleus139.75
Cerebellum25.15
CerebellumPeduncles45.65
CiliaryGanglion43.25
CingulateCortex73.35
Colorectaladenocarcinoma31.2
DorsalRootGanglion48.35
FetalThyroid46.9
Fetalbrain36.35
Fetalliver206.9
Fetallung71.25
GlobusPallidus37.85
Heart80.75
Hypothalamus83.4
Kidney22
Leukemia_chronicMyelogenousK-56282.35
Leukemia_promyelocytic-HL-6023.4
Leukemialymphoblastic(MOLT-4)22.9
Liver1289.15
Lung164.4
Lymphnode94.25
Lymphoma_burkitts(Daudi)41.1
Lymphoma_burkitts(Raji)43.65
MedullaOblongata90
OccipitalLobe49.3
OlfactoryBulb70.3
Ovary30.65
Pancreas39.45
PancreaticIslet42.55
ParietalLobe48.1
Pituitary55.3
Placenta39.2
Pons85.7
PrefrontalCortex47.65
Prostate62.6
Salivarygland24.9
SkeletalMuscle55.9
Skin52
SmoothMuscle21.6
Spinalcord123.55
SubthalamicNucleus46.95
SuperiorCervicalGanglion81.6
TemporalLobe41.8
Testis38.5
TestisGermCell33.65
TestisIntersitial29.45
TestisLeydigCell42.95
TestisSeminiferousTubule41.7
Thalamus99.05
Thymus43.3
Thyroid42.25
Tongue42.95
Tonsil80.9
Trachea27.55
TrigeminalGanglion63.2
Uterus22.85
UterusCorpus70.85
WholeBlood26.35
Wholebrain37.55
colon25
pineal_day40.34
pineal_night38.28
retina49.3
small_intestine25.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P109214
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.93 ± 0.55
Basal Forebrain8.03 ± 0.44
Basal Part of Pons7.18 ± 1.19
Cerebellar Cortex5.6 ± 0.55
Cerebellar Nuclei6.22 ± 1
Claustrum6.32 ± 1.26
Epithalamus6.79 ± 0.98
Frontal Lobe6.51 ± 0.9
Globus Pallidus10.02 ± 1.15
Hypothalamus8.23 ± 0.43
Insula6.9 ± 0.85
Limbic Lobe6.13 ± 1.31
Mesencephalon7.84 ± 1.39
Myelencephalon6.91 ± 1.29
Occipital Lobe6.96 ± 0.9
Parietal Lobe6.79 ± 0.81
Pontine Tegmentum7.06 ± 1.07
Striatum10.37 ± 1.42
Subthalamus6.29 ± 0.36
Temporal Lobe7.24 ± 0.71
Thalamus8.38 ± 0.8
White Matter6 ± 0.51
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Apoc1CBCerebellum55.19
87.03
Apoc1CTXCerebral cortex87.37
83.02
Apoc1HIPHippocampal region27.12
32.35
Apoc1HPFHippocampal formation32.15
32.47
Apoc1HYHypothalamus12.12
9.37
Apoc1LSXLateral septal complex6.06
4.26
Apoc1MBMidbrain34.05
32.92
Apoc1MYMedulla35.78
39.9
Apoc1OLFOlfactory bulb76.12
83.13
Apoc1PPons27.16
28.31
Apoc1PALPallidum34.46
34.29
Apoc1RHPRetrohippocampal region40.52
33.04
Apoc1sAMYStriatum-like amygdalar nuclei31.41
24.45
Apoc1STRStriatum44.38
36.75
Apoc1STRdStriatum dorsal region43.27
33.32
Apoc1STRvStriatum ventral region72.99
66.24
Apoc1THThalamus38.21
32.02
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
APOC1_HUMAN_27 23 27 49 TPDVSSALDKLKEFGNTLEDKAR PRIDE
PAp00024794 21 29 49 DVSSALDKLKEFGNTLEDKAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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