AutismKB 2.0

Annotation Detail for FMN1


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Basic Information Top
Gene Symbol:FMN1 ( DKFZp686C2281,DKFZp686G2387,FLJ45135,FMN,LD,MGC125288,MGC125289 )
Gene Full Name: formin 1
Band: 15q13.3
Quick LinksEntrez ID:342184; OMIM: 136535; Uniprot ID:C9IYD7_HUMAN; ENSEMBL ID: ENSG00000186031; HGNC ID: 3768
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal48 / 336030714
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor8 / 12494964
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone5 / 7165569
bone marrow1 / 4880120
brain10 / 11009899
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine3 / 23447212
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland9 / 15327158
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin17 / 21057480
spleen0 / 539520 
stomach5 / 9661951
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_942_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.02 ± 1.26
Basal Forebrain3.39 ± 0.55
Basal Part of Pons4.25 ± 1.21
Cerebellar Cortex3.11 ± 0.49
Cerebellar Nuclei4.41 ± 0.42
Claustrum5.14 ± 0.5
Epithalamus3.28 ± 0.75
Frontal Lobe3.87 ± 0.68
Globus Pallidus3.25 ± 1
Hypothalamus3.51 ± 0.76
Insula3.72 ± 0.62
Limbic Lobe3.7 ± 0.67
Mesencephalon4.09 ± 0.83
Myelencephalon3.77 ± 0.72
Occipital Lobe4.72 ± 0.6
Parietal Lobe4.44 ± 0.68
Pontine Tegmentum3.82 ± 0.79
Striatum2.78 ± 1.16
Subthalamus3.79 ± 1.2
Temporal Lobe3.84 ± 0.75
Thalamus3.51 ± 0.72
White Matter3.24 ± 0.71
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fmn1CBCerebellum0.74
1.61
Fmn1CTXCerebral cortex0.69
1.13
Fmn1HIPHippocampal region0.65
0.87
Fmn1HPFHippocampal formation0.63
0.97
Fmn1HYHypothalamus0.1
0.12
Fmn1LSXLateral septal complex0.06
0.06
Fmn1MBMidbrain0.2
0.35
Fmn1MYMedulla2.09
2.53
Fmn1OLFOlfactory bulb0.83
0.95
Fmn1PPons0.21
0.28
Fmn1PALPallidum0.56
0.58
Fmn1RHPRetrohippocampal region0.57
1.15
Fmn1sAMYStriatum-like amygdalar nuclei1.11
0.99
Fmn1STRStriatum1.81
2.57
Fmn1STRdStriatum dorsal region2.68
3.9
Fmn1STRvStriatum ventral region0.19
0.19
Fmn1THThalamus0.99
1.84
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018