AutismKB 2.0

Annotation Detail for IFIT1


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Basic Information Top
Gene Symbol:IFIT1 ( C56,G10P1,GARG-16,IFI-56,IFI-56K,IFI56,IFIT-1,IFNAI1,ISG56,RNM561 )
Gene Full Name: interferon-induced protein with tetratricopeptide repeats 1
Band: 10q23.31
Quick LinksEntrez ID:3434; OMIM: 147690; Uniprot ID:IFIT1_HUMAN; ENSEMBL ID: ENSG00000185745; HGNC ID: 5407
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus38 / 56401267
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult148 / 193912176
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor21 / 94178222
cervical tumor7 / 34366203
chondrosarcoma13 / 82823156
colorectal tumor15 / 114246131
esophageal tumor10 / 17290578
gastrointestinal tumor3 / 11936925
germ cell tumor4 / 26384515
glioma7 / 10688365
head and neck tumor4 / 13630229
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor9 / 9635993
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia21 / 97250215
normal248 / 336030773
ovarian tumor6 / 7668278
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor31 / 125191247
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland5 / 33197150
ascites0 / 400150 
bladder10 / 29757336
blood17 / 123478137
bone9 / 71655125
bone marrow0 / 488010 
brain95 / 110098986
cervix9 / 48171186
connective tissue15 / 149255100
ear1 / 1621261
embryonic tissue1 / 2157224
esophagus11 / 20209544
eye10 / 21105447
heart17 / 89626189
intestine23 / 23447298
kidney16 / 21177775
larynx0 / 241450 
liver14 / 20774367
lung23 / 33697468
lymph0 / 442700 
lymph node0 / 916100 
mammary gland25 / 153271163
mouth1 / 6705214
muscle5 / 10771546
nerve1 / 1576863
ovary9 / 10205188
pancreas6 / 21481227
parathyroid2 / 2053997
pharynx5 / 41328120
pituitary gland2 / 16585120
placenta23 / 28082581
prostate5 / 18934526
salivary gland0 / 201550 
skin14 / 21057466
spleen4 / 5395274
stomach4 / 9661941
testis9 / 33044227
thymus3 / 8113136
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus52 / 232878223
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203153_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.15
Adipocyte6.7
AdrenalCortex8.2
Adrenalgland6
Amygdala17.1
Appendix7.95
AtrioventricularNode5.1
BDCA4+_DentriticCells6.55
Bonemarrow6.05
BronchialEpithelialCells5.7
CD105+_Endothelial6.6
CD14+_Monocytes23.2
CD19+_BCells(neg._sel.)5.9
CD33+_Myeloid8.2
CD34+8.25
CD4+_Tcells5.65
CD56+_NKCells6.35
CD71+_EarlyErythroid6.35
CD8+_Tcells4.9
CardiacMyocytes8.75
Caudatenucleus14.75
Cerebellum8.4
CerebellumPeduncles9.3
CiliaryGanglion4.7
CingulateCortex13.6
Colorectaladenocarcinoma5.7
DorsalRootGanglion6.5
FetalThyroid5.65
Fetalbrain5.75
Fetalliver6.1
Fetallung4.7
GlobusPallidus14.35
Heart8.75
Hypothalamus34.4
Kidney6.15
Leukemia_chronicMyelogenousK-5625.4
Leukemia_promyelocytic-HL-605.1
Leukemialymphoblastic(MOLT-4)4.75
Liver8.9
Lung6.7
Lymphnode8.7
Lymphoma_burkitts(Daudi)23.95
Lymphoma_burkitts(Raji)8.5
MedullaOblongata11.35
OccipitalLobe9.9
OlfactoryBulb7.35
Ovary4.4
Pancreas5.25
PancreaticIslet6.3
ParietalLobe10.1
Pituitary19.3
Placenta5.75
Pons11.1
PrefrontalCortex26.1
Prostate6.75
Salivarygland5.55
SkeletalMuscle8.85
Skin5.35
SmoothMuscle9.5
Spinalcord25.65
SubthalamicNucleus14.45
SuperiorCervicalGanglion8.55
TemporalLobe9.95
Testis4.9
TestisGermCell9.05
TestisIntersitial5.35
TestisLeydigCell5.85
TestisSeminiferousTubule5.1
Thalamus15.25
Thymus4.45
Thyroid11.15
Tongue10.95
Tonsil14.75
Trachea5.3
TrigeminalGanglion6.55
Uterus5.9
UterusCorpus6.45
WholeBlood111.25
Wholebrain8.05
colon7
pineal_day34.12
pineal_night35.66
retina10.225
small_intestine5.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10053_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.72 ± 1.1
Basal Forebrain2.17 ± 0.38
Basal Part of Pons1.87 ± 0.74
Cerebellar Cortex2.23 ± 0.72
Cerebellar Nuclei2.52 ± 0.96
Claustrum2.72 ± 0.72
Epithalamus2.47 ± 0.58
Frontal Lobe2.09 ± 0.71
Globus Pallidus3.06 ± 0.54
Hypothalamus2.2 ± 0.74
Insula2.23 ± 0.88
Limbic Lobe2.25 ± 0.73
Mesencephalon2.3 ± 0.77
Myelencephalon2.36 ± 0.71
Occipital Lobe2.47 ± 0.75
Parietal Lobe2.28 ± 0.81
Pontine Tegmentum2.35 ± 0.69
Striatum2.32 ± 0.8
Subthalamus2.49 ± 1.12
Temporal Lobe2.18 ± 0.73
Thalamus2.25 ± 0.74
White Matter3.13 ± 0.93
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ifit1CBCerebellum0
0
Ifit1CTXCerebral cortex0
0
Ifit1HIPHippocampal region0
0
Ifit1HPFHippocampal formation0
0
Ifit1HYHypothalamus0
0
Ifit1LSXLateral septal complex0
0
Ifit1MBMidbrain0
0
Ifit1MYMedulla0
0
Ifit1OLFOlfactory bulb0
0
Ifit1PPons0
0
Ifit1PALPallidum0
0
Ifit1RHPRetrohippocampal region0
0
Ifit1sAMYStriatum-like amygdalar nuclei0
0
Ifit1STRStriatum0
0
Ifit1STRdStriatum dorsal region0
0
Ifit1STRvStriatum ventral region0
0
Ifit1THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00004674 17 111 127 LAEAQTYLDKVENICKK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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