AutismKB 2.0

Annotation Detail for IFNA4


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Basic Information Top
Gene Symbol:IFNA4 ( IFN-alpha4a,INFA4,MGC142200 )
Gene Full Name: interferon, alpha 4
Band: 9p21.3
Quick LinksEntrez ID:3441; OMIM: 147564; Uniprot ID:IFNA4_HUMAN; ENSEMBL ID: ENSG00000236637; HGNC ID: 5425
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208261_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts5
Adipocyte4.1
AdrenalCortex4.4
Adrenalgland3.5
Amygdala4.3
Appendix4.45
AtrioventricularNode3.75
BDCA4+_DentriticCells4.4
Bonemarrow4.15
BronchialEpithelialCells4.05
CD105+_Endothelial4.15
CD14+_Monocytes4.35
CD19+_BCells(neg._sel.)4.3
CD33+_Myeloid5.3
CD34+5.2
CD4+_Tcells4.45
CD56+_NKCells4.95
CD71+_EarlyErythroid3.85
CD8+_Tcells3.95
CardiacMyocytes5.3
Caudatenucleus3.7
Cerebellum3.35
CerebellumPeduncles4.65
CiliaryGanglion3.15
CingulateCortex4.2
Colorectaladenocarcinoma4.15
DorsalRootGanglion3.25
FetalThyroid4
Fetalbrain4.1
Fetalliver3.55
Fetallung3.4
GlobusPallidus3.1
Heart5.25
Hypothalamus4.55
Kidney3.35
Leukemia_chronicMyelogenousK-5623.75
Leukemia_promyelocytic-HL-603.65
Leukemialymphoblastic(MOLT-4)3.35
Liver5.4
Lung4.55
Lymphnode3.5
Lymphoma_burkitts(Daudi)5.25
Lymphoma_burkitts(Raji)5.75
MedullaOblongata3.8
OccipitalLobe3.7
OlfactoryBulb3.25
Ovary2.75
Pancreas3.35
PancreaticIslet4.4
ParietalLobe4.4
Pituitary4.8
Placenta4.25
Pons3.95
PrefrontalCortex5.1
Prostate4.8
Salivarygland3.3
SkeletalMuscle4.75
Skin3.35
SmoothMuscle4.7
Spinalcord4.4
SubthalamicNucleus3.75
SuperiorCervicalGanglion5.05
TemporalLobe3.75
Testis3.55
TestisGermCell3.5
TestisIntersitial3.45
TestisLeydigCell4.1
TestisSeminiferousTubule3.55
Thalamus4.15
Thymus3.25
Thyroid5.15
Tongue4.15
Tonsil4
Trachea3.45
TrigeminalGanglion4.35
Uterus3.4
UterusCorpus3.7
WholeBlood4.55
Wholebrain3.4
colon4.15
pineal_day5.12
pineal_night5
retina4.975
small_intestine3.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P403459
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.49 ± 0.58
Basal Forebrain4.92 ± 0.37
Basal Part of Pons4.13 ± 0.62
Cerebellar Cortex4.3 ± 0.6
Cerebellar Nuclei4.23 ± 0.44
Claustrum4.69 ± 0.63
Epithalamus4.03 ± 0.46
Frontal Lobe4.21 ± 0.64
Globus Pallidus5.56 ± 0.41
Hypothalamus3.84 ± 0.67
Insula4.01 ± 0.66
Limbic Lobe4.46 ± 0.73
Mesencephalon4.59 ± 0.67
Myelencephalon4.45 ± 0.65
Occipital Lobe4.73 ± 0.59
Parietal Lobe4.45 ± 0.63
Pontine Tegmentum4.42 ± 0.58
Striatum4.87 ± 0.6
Subthalamus3.85 ± 0.34
Temporal Lobe4.28 ± 0.63
Thalamus4.56 ± 0.42
White Matter5.82 ± 0.31
Mouse Brain ISH
Peptide Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018