Annotation Detail for APOC3
Basic Information Top
| Gene Symbol: | APOC3 ( APOCIII,MGC150353 ) |
|---|---|
| Gene Full Name: | apolipoprotein C-III |
| Band: | 11q23.3 |
| Quick Links | Entrez ID:345; OMIM: 107720; Uniprot ID:APOC3_HUMAN; ENSEMBL ID: ENSG00000110245; HGNC ID: 610 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.73849
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 56 / 564012 | 99 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 67 / 1939121 | 34 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 1 / 263845 | 3 |  |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 14 / 96359 | 145 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 115 / 3360307 | 34 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 2 / 1100989 | 1 |  |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 1 / 215722 | 4 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 2 / 89626 | 22 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 6 / 211777 | 28 | |
| larynx | 0 / 24145 | 0 | |
| liver | 70 / 207743 | 336 |  |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 10 / 53952 | 185 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 205820_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6 | |
| Adipocyte | 4.9 | |
| AdrenalCortex | 5.35 | |
| Adrenalgland | 4.2 | |
| Amygdala | 5.05 | |
| Appendix | 5.2 | |
| AtrioventricularNode | 4.15 | |
| BDCA4+_DentriticCells | 5.15 | |
| Bonemarrow | 5 | |
| BronchialEpithelialCells | 4.9 | |
| CD105+_Endothelial | 4.8 | |
| CD14+_Monocytes | 5.2 | |
| CD19+_BCells(neg._sel.) | 5.15 | |
| CD33+_Myeloid | 6.2 | |
| CD34+ | 5.95 | |
| CD4+_Tcells | 5.2 | |
| CD56+_NKCells | 5.6 | |
| CD71+_EarlyErythroid | 4.65 | |
| CD8+_Tcells | 4.8 | |
| CardiacMyocytes | 6.9 | |
| Caudatenucleus | 4.4 | |
| Cerebellum | 4 | |
| CerebellumPeduncles | 5.7 | |
| CiliaryGanglion | 3.55 | |
| CingulateCortex | 5.05 | |
| Colorectaladenocarcinoma | 4.9 | |
| DorsalRootGanglion | 3.95 | |
| FetalThyroid | 5.7 | |
| Fetalbrain | 4.9 | |
| Fetalliver | 3071.75 |  |
| Fetallung | 1976.1 | |
| GlobusPallidus | 3.6 | |
| Heart | 6.75 | |
| Hypothalamus | 5.2 | |
| Kidney | 4.2 | |
| Leukemia_chronicMyelogenousK-562 | 4.45 | |
| Leukemia_promyelocytic-HL-60 | 4.35 | |
| Leukemialymphoblastic(MOLT-4) | 3.95 | |
| Liver | 27381.5 | |
| Lung | 5.4 | |
| Lymphnode | 4.2 | |
| Lymphoma_burkitts(Daudi) | 6.35 | |
| Lymphoma_burkitts(Raji) | 7.15 | |
| MedullaOblongata | 4.55 | |
| OccipitalLobe | 4.3 | |
| OlfactoryBulb | 3.9 | |
| Ovary | 3.3 | |
| Pancreas | 4 | |
| PancreaticIslet | 5.3 | |
| ParietalLobe | 5.35 | |
| Pituitary | 5.75 | |
| Placenta | 5 | |
| Pons | 4.7 | |
| PrefrontalCortex | 6 | |
| Prostate | 27.8 | |
| Salivarygland | 4.15 | |
| SkeletalMuscle | 8.65 | |
| Skin | 4 | |
| SmoothMuscle | 5.5 | |
| Spinalcord | 5.3 | |
| SubthalamicNucleus | 4.5 | |
| SuperiorCervicalGanglion | 6.05 | |
| TemporalLobe | 4.5 | |
| Testis | 4.2 | |
| TestisGermCell | 4.15 | |
| TestisIntersitial | 4.15 | |
| TestisLeydigCell | 5.35 | |
| TestisSeminiferousTubule | 4.55 | |
| Thalamus | 5 | |
| Thymus | 3.75 | |
| Thyroid | 6.05 | |
| Tongue | 5.05 | |
| Tonsil | 4.8 | |
| Trachea | 4.15 | |
| TrigeminalGanglion | 5.05 | |
| Uterus | 4 | |
| UterusCorpus | 7.2 | |
| WholeBlood | 5.4 | |
| Wholebrain | 4.2 | |
| colon | 4.95 | |
| pineal_day | 6.06 | |
| pineal_night | 5.96 | |
| retina | 5.95 | |
| small_intestine | 3148.9 | |
- Probe name: A_23_P203183
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.32 ± 1.17 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.73 ± 0.19 | |
| Basal Part of Pons | 1.29 ± 0.39 | |
| Cerebellar Cortex | 1.62 ± 0.81 | |
| Cerebellar Nuclei | 2.29 ± 1.16 | |
| Claustrum | 2.71 ± 0.96 | |
| Epithalamus | 1.53 ± 0.79 | |
| Frontal Lobe | 1.63 ± 0.77 | |
| Globus Pallidus | 2.53 ± 0.52 | |
| Hypothalamus | 1.92 ± 0.85 | |
| Insula | 1.57 ± 0.42 | |
| Limbic Lobe | 1.75 ± 0.66 | |
| Mesencephalon | 1.99 ± 0.92 | |
| Myelencephalon | 1.81 ± 0.82 | |
| Occipital Lobe | 1.75 ± 0.58 | |
| Parietal Lobe | 1.82 ± 1.03 | |
| Pontine Tegmentum | 1.9 ± 0.87 | |
| Striatum | 1.89 ± 0.54 | |
| Subthalamus | 1.81 ± 0.63 | |
| Temporal Lobe | 1.74 ± 0.82 | |
| Thalamus | 1.71 ± 0.65 | |
| White Matter | 2.14 ± 0.14 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Apoc3 | CB | Cerebellum | 17.56 | |
| 19.24 | | |||
| Apoc3 | CTX | Cerebral cortex | 51.04 | |
| 36.81 | | |||
| Apoc3 | HIP | Hippocampal region | 33.5 | |
| 37.41 | | |||
| Apoc3 | HPF | Hippocampal formation | 44.09 | |
| 42.7 | | |||
| Apoc3 | HY | Hypothalamus | 21.42 | |
| 15.11 | | |||
| Apoc3 | LSX | Lateral septal complex | 20.12 | |
| 13.44 | | |||
| Apoc3 | MB | Midbrain | 18.91 | |
| 14.85 | | |||
| Apoc3 | MY | Medulla | 21.91 | |
| 19.95 | | |||
| Apoc3 | OLF | Olfactory bulb | 56.88 | |
| 48.49 | | |||
| Apoc3 | P | Pons | 20.34 | |
| 20.08 | | |||
| Apoc3 | PAL | Pallidum | 17.88 | |
| 13.32 | | |||
| Apoc3 | RHP | Retrohippocampal region | 67.44 | |
| 54.57 | | |||
| Apoc3 | sAMY | Striatum-like amygdalar nuclei | 24.62 | |
| 15.56 | | |||
| Apoc3 | STR | Striatum | 22.35 | |
| 14.33 | | |||
| Apoc3 | STRd | Striatum dorsal region | 23.85 | |
| 15.38 | | |||
| Apoc3 | STRv | Striatum ventral region | 20.02 | |
| 12.63 | | |||
| Apoc3 | TH | Thalamus | 46.32 | |
| 39.76 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00024575 | 16 | 45 | 60 | DALSSVQESQVAQQAR | Peptide Atlas |