AutismKB 2.0

Annotation Detail for IFNGR1


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Basic Information Top
Gene Symbol:IFNGR1 ( CD119,FLJ45734,IFNGR )
Gene Full Name: interferon gamma receptor 1
Band: 6q23.3
Quick LinksEntrez ID:3459; OMIM: 107470; Uniprot ID:INGR1_HUMAN; ENSEMBL ID: ENSG00000027697; HGNC ID: 5439
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst4 / 6231964
fetus25 / 56401244
neonate10 / 31097321
infant1 / 2362042
juvenile7 / 55556125
adult102 / 193912152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor5 / 17290289
gastrointestinal tumor3 / 11936925
germ cell tumor16 / 26384560
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor6 / 6895987
leukemia4 / 9584241
liver tumor12 / 96359124
lung tumor3 / 10312729
lymphoma2 / 7175527
non-neoplasia13 / 97250133
normal310 / 336030792
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer1 / 1026809
retinoblastoma4 / 4635686
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland1 / 3319730
ascites1 / 4001524
bladder7 / 29757235
blood35 / 123478283
bone3 / 7165541
bone marrow0 / 488010 
brain125 / 1100989113
cervix5 / 48171103
connective tissue18 / 149255120
ear1 / 1621261
embryonic tissue13 / 21572260
esophagus6 / 20209296
eye9 / 21105442
heart14 / 89626156
intestine13 / 23447255
kidney14 / 21177766
larynx0 / 241450 
liver17 / 20774381
lung28 / 33697483
lymph0 / 442700 
lymph node5 / 9161054
mammary gland2 / 15327113
mouth1 / 6705214
muscle15 / 107715139
nerve2 / 15768126
ovary4 / 10205139
pancreas10 / 21481246
parathyroid2 / 2053997
pharynx13 / 41328314
pituitary gland0 / 165850 
placenta28 / 28082599
prostate10 / 18934552
salivary gland2 / 2015599
skin6 / 21057428
spleen9 / 53952166
stomach3 / 9661931
testis7 / 33044221
thymus5 / 8113161
thyroid0 / 474730 
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus15 / 23287864
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211676_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts226.4
Adipocyte123.3
AdrenalCortex23.8
Adrenalgland12
Amygdala35.2
Appendix23.85
AtrioventricularNode21.05
BDCA4+_DentriticCells217.4
Bonemarrow16.9
BronchialEpithelialCells57.05
CD105+_Endothelial10.35
CD14+_Monocytes376.7
CD19+_BCells(neg._sel.)30.3
CD33+_Myeloid350.25
CD34+33.4
CD4+_Tcells39.2
CD56+_NKCells76.4
CD71+_EarlyErythroid11.15
CD8+_Tcells68.55
CardiacMyocytes25.5
Caudatenucleus23
Cerebellum9.1
CerebellumPeduncles18.2
CiliaryGanglion18.1
CingulateCortex15.75
Colorectaladenocarcinoma7.85
DorsalRootGanglion14.3
FetalThyroid20.3
Fetalbrain23.3
Fetalliver12.3
Fetallung185.15
GlobusPallidus13.6
Heart11.1
Hypothalamus54.95
Kidney9.65
Leukemia_chronicMyelogenousK-56240.5
Leukemia_promyelocytic-HL-6023.95
Leukemialymphoblastic(MOLT-4)8.8
Liver9.8
Lung17.6
Lymphnode86.25
Lymphoma_burkitts(Daudi)17.2
Lymphoma_burkitts(Raji)31.2
MedullaOblongata13.9
OccipitalLobe32.35
OlfactoryBulb58.75
Ovary22.9
Pancreas29.8
PancreaticIslet34.65
ParietalLobe19.05
Pituitary26.35
Placenta145.75
Pons13.55
PrefrontalCortex55.6
Prostate22.65
Salivarygland51.9
SkeletalMuscle12.1
Skin22.65
SmoothMuscle23.65
Spinalcord101.15
SubthalamicNucleus15.3
SuperiorCervicalGanglion19.2
TemporalLobe15.35
Testis6.15
TestisGermCell28.8
TestisIntersitial15.2
TestisLeydigCell17.05
TestisSeminiferousTubule12.1
Thalamus32.6
Thymus10.8
Thyroid27.5
Tongue16.55
Tonsil162.8
Trachea43.35
TrigeminalGanglion19.95
Uterus48.1
UterusCorpus23.65
WholeBlood652.3
Wholebrain18.6
colon60.9
pineal_day39.06
pineal_night36.86
retina52.475
small_intestine64.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14999_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.36 ± 0.51
Basal Forebrain7.68 ± 0.27
Basal Part of Pons7.82 ± 0.24
Cerebellar Cortex7.57 ± 0.18
Cerebellar Nuclei8.55 ± 0.33
Claustrum7.33 ± 0.54
Epithalamus8.13 ± 0.41
Frontal Lobe7.72 ± 0.36
Globus Pallidus8.85 ± 0.27
Hypothalamus7.9 ± 0.46
Insula7.79 ± 0.29
Limbic Lobe7.63 ± 0.32
Mesencephalon7.88 ± 0.42
Myelencephalon7.78 ± 0.42
Occipital Lobe7.96 ± 0.33
Parietal Lobe7.74 ± 0.37
Pontine Tegmentum7.84 ± 0.34
Striatum7.88 ± 0.32
Subthalamus8.23 ± 0.51
Temporal Lobe7.66 ± 0.3
Thalamus7.91 ± 0.24
White Matter9.47 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ifngr1CBCerebellum14.32
19.14
Ifngr1CTXCerebral cortex17.29
11.85
Ifngr1HIPHippocampal region8.15
8.14
Ifngr1HPFHippocampal formation11.8
11.37
Ifngr1HYHypothalamus3.62
2.71
Ifngr1LSXLateral septal complex2.64
1.73
Ifngr1MBMidbrain7.15
7.24
Ifngr1MYMedulla15.06
17.18
Ifngr1OLFOlfactory bulb19.32
14.14
Ifngr1PPons9.82
10.94
Ifngr1PALPallidum6.9
5.92
Ifngr1RHPRetrohippocampal region17.33
15.29
Ifngr1sAMYStriatum-like amygdalar nuclei5.22
3.68
Ifngr1STRStriatum8.91
5.78
Ifngr1STRdStriatum dorsal region11.39
7.48
Ifngr1STRvStriatum ventral region5.05
3.12
Ifngr1THThalamus9.8
8
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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