AutismKB 2.0

Annotation Detail for IGFBPL1


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Basic Information Top
Gene Symbol:IGFBPL1 ( IGFBP-RP4,bA113O24.1 )
Gene Full Name: insulin-like growth factor binding protein-like 1
Band: 9p13.1
Quick LinksEntrez ID:347252; OMIM: 610413; Uniprot ID:IBPL1_HUMAN; ENSEMBL ID: ENSG00000137142; HGNC ID: 20081
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst4 / 6231964
fetus10 / 56401217
neonate0 / 310970 
infant8 / 23620338
juvenile0 / 555560 
adult20 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal42 / 336030712
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain25 / 110098922
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve3 / 15768190
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta4 / 28082514
prostate2 / 18934510
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5960_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.72 ± 0.53
Basal Forebrain4.43 ± 0.37
Basal Part of Pons4.35 ± 0.5
Cerebellar Cortex4.71 ± 0.41
Cerebellar Nuclei4.33 ± 0.43
Claustrum4.64 ± 0.64
Epithalamus4.03 ± 0.49
Frontal Lobe4.47 ± 0.56
Globus Pallidus3.82 ± 0.78
Hypothalamus4.2 ± 0.43
Insula4.56 ± 0.61
Limbic Lobe4.71 ± 0.57
Mesencephalon4.72 ± 0.54
Myelencephalon4.58 ± 0.57
Occipital Lobe4.32 ± 0.68
Parietal Lobe4.48 ± 0.5
Pontine Tegmentum4.37 ± 0.56
Striatum5.44 ± 0.47
Subthalamus4.4 ± 0.76
Temporal Lobe4.49 ± 0.52
Thalamus4.36 ± 0.54
White Matter3.53 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Igfbpl1CBCerebellum100
100
Igfbpl1CTXCerebral cortex100
100
Igfbpl1HIPHippocampal region98.14
100
Igfbpl1HPFHippocampal formation100
100
Igfbpl1HYHypothalamus100
100
Igfbpl1LSXLateral septal complex100
100
Igfbpl1MBMidbrain100
100
Igfbpl1MYMedulla100
100
Igfbpl1OLFOlfactory bulb100
100
Igfbpl1PPons100
100
Igfbpl1PALPallidum100
100
Igfbpl1RHPRetrohippocampal region100
100
Igfbpl1sAMYStriatum-like amygdalar nuclei100
100
Igfbpl1STRStriatum100
100
Igfbpl1STRdStriatum dorsal region100
100
Igfbpl1STRvStriatum ventral region100
100
Igfbpl1THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018