AutismKB 2.0

Annotation Detail for SERINC2


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Basic Information Top
Gene Symbol:SERINC2 ( MGC90340,PRO0899,TDE2,TDE2L )
Gene Full Name: serine incorporator 2
Band: 1p35.2
Quick LinksEntrez ID:347735; OMIM: NA; Uniprot ID:B4DJK5_HUMAN; ENSEMBL ID: ENSG00000168528; HGNC ID: 23231
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus19 / 56401233
neonate2 / 3109764
infant1 / 2362042
juvenile4 / 5555671
adult232 / 1939121119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma4 / 17475228
breast (mammary gland) tumor25 / 94178265
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor17 / 114246148
esophageal tumor1 / 1729057
gastrointestinal tumor9 / 11936975
germ cell tumor2 / 2638457
glioma5 / 10688346
head and neck tumor5 / 13630236
kidney tumor5 / 6895972
leukemia10 / 95842104
liver tumor6 / 9635962
lung tumor9 / 10312787
lymphoma10 / 71755139
non-neoplasia4 / 9725041
normal194 / 336030757
ovarian tumor7 / 7668291
pancreatic tumor20 / 104616191
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer9 / 10268087
retinoblastoma0 / 463560 
skin tumor11 / 12494988
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor21 / 90257232
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites6 / 40015149
bladder6 / 29757201
blood10 / 12347880
bone6 / 7165583
bone marrow0 / 488010 
brain18 / 110098916
cervix6 / 48171124
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye7 / 21105433
heart3 / 8962633
intestine24 / 234472102
kidney26 / 211777122
larynx2 / 2414582
liver19 / 20774391
lung27 / 33697480
lymph2 / 4427045
lymph node0 / 916100 
mammary gland56 / 153271365
mouth3 / 6705244
muscle3 / 10771527
nerve0 / 157680 
ovary7 / 10205168
pancreas26 / 214812121
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta47 / 280825167
prostate26 / 189345137
salivary gland0 / 201550 
skin19 / 21057490
spleen0 / 539520 
stomach4 / 9661941
testis4 / 33044212
thymus9 / 81131110
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus26 / 232878111
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P147331
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.31 ± 1.13
Basal Forebrain1.95 ± 0.4
Basal Part of Pons1.62 ± 0.56
Cerebellar Cortex1.95 ± 0.9
Cerebellar Nuclei2.13 ± 0.75
Claustrum2.88 ± 1.02
Epithalamus1.63 ± 0.83
Frontal Lobe1.72 ± 0.74
Globus Pallidus2.41 ± 0.54
Hypothalamus1.74 ± 0.68
Insula1.63 ± 0.65
Limbic Lobe1.96 ± 0.72
Mesencephalon2.07 ± 0.89
Myelencephalon1.94 ± 0.76
Occipital Lobe1.94 ± 0.74
Parietal Lobe1.94 ± 0.92
Pontine Tegmentum1.92 ± 0.66
Striatum2.01 ± 0.68
Subthalamus1.89 ± 0.75
Temporal Lobe1.79 ± 0.67
Thalamus1.85 ± 0.65
White Matter2.04 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Serinc2CBCerebellum28.15
38.31
Serinc2CTXCerebral cortex37.2
14.07
Serinc2HIPHippocampal region16.69
11.3
Serinc2HPFHippocampal formation14.45
8.07
Serinc2HYHypothalamus0.23
0.13
Serinc2LSXLateral septal complex0.42
0.24
Serinc2MBMidbrain1.65
2.05
Serinc2MYMedulla6.25
4.45
Serinc2OLFOlfactory bulb7.27
3.27
Serinc2PPons7.27
3.82
Serinc2PALPallidum0.68
1.15
Serinc2RHPRetrohippocampal region11.06
4.07
Serinc2sAMYStriatum-like amygdalar nuclei0.56
0.29
Serinc2STRStriatum1.92
1.19
Serinc2STRdStriatum dorsal region2.27
1.32
Serinc2STRvStriatum ventral region1.79
1.37
Serinc2THThalamus2.33
1.06
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00429654 28 68 95 LPWVCEEGAGIPTVLQGHIDCGSLLGYR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018