AutismKB 2.0

Annotation Detail for IGF2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:IGF2 ( C11orf43,FLJ22066,FLJ44734,IGF-II,PP9974 )
Gene Full Name: insulin-like growth factor 2 (somatomedin A)
Band: 11p15.5
Quick LinksEntrez ID:3481; OMIM: 147470; Uniprot ID:IGF2_HUMAN; ENSEMBL ID: ENSG00000129965,ENSG00000167244; HGNC ID: 5466
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body158 / 707612232
blastocyst6 / 6231996
fetus448 / 564012794
neonate0 / 310970 
infant1 / 2362042
juvenile4 / 5555671
adult1154 / 1939121595
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202410_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.45
Adipocyte4.9
AdrenalCortex7.3
Adrenalgland7.05
Amygdala4.85
Appendix5.45
AtrioventricularNode4.2
BDCA4+_DentriticCells4.9
Bonemarrow5.85
BronchialEpithelialCells4.6
CD105+_Endothelial4.7
CD14+_Monocytes4.9
CD19+_BCells(neg._sel.)4.8
CD33+_Myeloid5.75
CD34+5.75
CD4+_Tcells5
CD56+_NKCells5.35
CD71+_EarlyErythroid4.4
CD8+_Tcells4.3
CardiacMyocytes6.05
Caudatenucleus4.6
Cerebellum4
CerebellumPeduncles5.35
CiliaryGanglion3.6
CingulateCortex4.9
Colorectaladenocarcinoma5.1
DorsalRootGanglion3.9
FetalThyroid28.2
Fetalbrain4.6
Fetalliver730.05
Fetallung68.3
GlobusPallidus3.4
Heart7.2
Hypothalamus5.1
Kidney4.1
Leukemia_chronicMyelogenousK-5624.2
Leukemia_promyelocytic-HL-604.1
Leukemialymphoblastic(MOLT-4)3.75
Liver96.25
Lung5.3
Lymphnode4.1
Lymphoma_burkitts(Daudi)6.05
Lymphoma_burkitts(Raji)6.75
MedullaOblongata4.3
OccipitalLobe4.15
OlfactoryBulb33.85
Ovary3.1
Pancreas4.3
PancreaticIslet5.1
ParietalLobe5.05
Pituitary5.55
Placenta447.5
Pons4.8
PrefrontalCortex5.9
Prostate5.45
Salivarygland3.75
SkeletalMuscle5.9
Skin4.5
SmoothMuscle5.4
Spinalcord5.6
SubthalamicNucleus4.35
SuperiorCervicalGanglion5.9
TemporalLobe4.35
Testis4
TestisGermCell3.9
TestisIntersitial4
TestisLeydigCell4.65
TestisSeminiferousTubule4.05
Thalamus4.95
Thymus3.65
Thyroid5.75
Tongue4.7
Tonsil4.55
Trachea3.9
TrigeminalGanglion6.55
Uterus17.85
UterusCorpus4.2
WholeBlood5.05
Wholebrain3.9
colon4.65
pineal_day5.74
pineal_night5.66
retina19.6
small_intestine4.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P936758
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.41 ± 0.66
Basal Forebrain6.19 ± 0.52
Basal Part of Pons5.89 ± 0.32
Cerebellar Cortex5.76 ± 0.35
Cerebellar Nuclei6.24 ± 0.32
Claustrum6.37 ± 0.55
Epithalamus5.52 ± 0.68
Frontal Lobe6.17 ± 0.55
Globus Pallidus6.6 ± 0.47
Hypothalamus6.1 ± 0.56
Insula6.07 ± 0.56
Limbic Lobe6.28 ± 0.58
Mesencephalon6.25 ± 0.56
Myelencephalon6.22 ± 0.55
Occipital Lobe6.18 ± 0.62
Parietal Lobe6.15 ± 0.53
Pontine Tegmentum6.08 ± 0.45
Striatum6.71 ± 0.51
Subthalamus5.72 ± 0.65
Temporal Lobe6.05 ± 0.61
Thalamus6.21 ± 0.5
White Matter5.85 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Igf2CBCerebellum7.9
9.81
Igf2CTXCerebral cortex29.63
18.07
Igf2HIPHippocampal region26.36
21.5
Igf2HPFHippocampal formation25.62
20.23
Igf2HYHypothalamus25.83
16.35
Igf2LSXLateral septal complex33.07
18.38
Igf2MBMidbrain18.81
14.92
Igf2MYMedulla8.03
9.47
Igf2OLFOlfactory bulb31.26
21.04
Igf2PPons29.54
21.28
Igf2PALPallidum29.09
18.22
Igf2RHPRetrohippocampal region24.55
18.3
Igf2sAMYStriatum-like amygdalar nuclei13.29
10.66
Igf2STRStriatum25.4
15.14
Igf2STRdStriatum dorsal region27.54
16.59
Igf2STRvStriatum ventral region20.23
10.29
Igf2THThalamus29.93
19.47
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00137404 8 113 120 FFQYDTWK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018