AutismKB 2.0

Annotation Detail for IGF2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:IGF2 ( C11orf43,FLJ22066,FLJ44734,IGF-II,PP9974 )
Gene Full Name: insulin-like growth factor 2 (somatomedin A)
Band: 11p15.5
Quick LinksEntrez ID:3481; OMIM: 147470; Uniprot ID:IGF2_HUMAN; ENSEMBL ID: ENSG00000129965,ENSG00000167244; HGNC ID: 5466
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body158 / 707612232
blastocyst6 / 6231996
fetus448 / 564012794
neonate0 / 310970 
infant1 / 2362042
juvenile4 / 5555671
adult1154 / 1939121595
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor23 / 127941797
bladder carcinoma17 / 17475972
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma12 / 82823144
colorectal tumor31 / 114246271
esophageal tumor2 / 17290115
gastrointestinal tumor0 / 1193690 
germ cell tumor7 / 26384526
glioma9 / 10688384
head and neck tumor7 / 13630251
kidney tumor44 / 68959638
leukemia6 / 9584262
liver tumor120 / 963591245
lung tumor6 / 10312758
lymphoma6 / 7175583
non-neoplasia13 / 97250133
normal1619 / 3360307481
ovarian tumor216 / 766822816
pancreatic tumor2999 / 10461628666
primitive neuroectodermal tumor of the CNS51 / 125680405
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor94 / 125191750
uterine tumor42 / 90257465
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue8 / 13106610
adrenal gland23 / 33197692
ascites0 / 400150 
bladder0 / 297570 
blood6 / 12347848
bone18 / 71655251
bone marrow3 / 4880161
brain208 / 1100989188
cervix1 / 4817120
connective tissue30 / 149255200
ear4 / 16212246
embryonic tissue186 / 215722862
esophagus2 / 2020998
eye25 / 211054118
heart37 / 89626412
intestine46 / 234472196
kidney52 / 211777245
larynx1 / 2414541
liver148 / 207743712
lung30 / 33697489
lymph3 / 4427067
lymph node3 / 9161032
mammary gland16 / 153271104
mouth5 / 6705274
muscle104 / 107715965
nerve31 / 157681966
ovary217 / 1020512126
pancreas3355 / 21481215618
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta436 / 2808251552
prostate1 / 1893455
salivary gland0 / 201550 
skin4 / 21057418
spleen30 / 53952556
stomach1 / 9661910
testis15 / 33044245
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus62 / 232878266
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202410_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.45
Adipocyte4.9
AdrenalCortex7.3
Adrenalgland7.05
Amygdala4.85
Appendix5.45
AtrioventricularNode4.2
BDCA4+_DentriticCells4.9
Bonemarrow5.85
BronchialEpithelialCells4.6
CD105+_Endothelial4.7
CD14+_Monocytes4.9
CD19+_BCells(neg._sel.)4.8
CD33+_Myeloid5.75
CD34+5.75
CD4+_Tcells5
CD56+_NKCells5.35
CD71+_EarlyErythroid4.4
CD8+_Tcells4.3
CardiacMyocytes6.05
Caudatenucleus4.6
Cerebellum4
CerebellumPeduncles5.35
CiliaryGanglion3.6
CingulateCortex4.9
Colorectaladenocarcinoma5.1
DorsalRootGanglion3.9
FetalThyroid28.2
Fetalbrain4.6
Fetalliver730.05
Fetallung68.3
GlobusPallidus3.4
Heart7.2
Hypothalamus5.1
Kidney4.1
Leukemia_chronicMyelogenousK-5624.2
Leukemia_promyelocytic-HL-604.1
Leukemialymphoblastic(MOLT-4)3.75
Liver96.25
Lung5.3
Lymphnode4.1
Lymphoma_burkitts(Daudi)6.05
Lymphoma_burkitts(Raji)6.75
MedullaOblongata4.3
OccipitalLobe4.15
OlfactoryBulb33.85
Ovary3.1
Pancreas4.3
PancreaticIslet5.1
ParietalLobe5.05
Pituitary5.55
Placenta447.5
Pons4.8
PrefrontalCortex5.9
Prostate5.45
Salivarygland3.75
SkeletalMuscle5.9
Skin4.5
SmoothMuscle5.4
Spinalcord5.6
SubthalamicNucleus4.35
SuperiorCervicalGanglion5.9
TemporalLobe4.35
Testis4
TestisGermCell3.9
TestisIntersitial4
TestisLeydigCell4.65
TestisSeminiferousTubule4.05
Thalamus4.95
Thymus3.65
Thyroid5.75
Tongue4.7
Tonsil4.55
Trachea3.9
TrigeminalGanglion6.55
Uterus17.85
UterusCorpus4.2
WholeBlood5.05
Wholebrain3.9
colon4.65
pineal_day5.74
pineal_night5.66
retina19.6
small_intestine4.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P936758
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.41 ± 0.66
Basal Forebrain6.19 ± 0.52
Basal Part of Pons5.89 ± 0.32
Cerebellar Cortex5.76 ± 0.35
Cerebellar Nuclei6.24 ± 0.32
Claustrum6.37 ± 0.55
Epithalamus5.52 ± 0.68
Frontal Lobe6.17 ± 0.55
Globus Pallidus6.6 ± 0.47
Hypothalamus6.1 ± 0.56
Insula6.07 ± 0.56
Limbic Lobe6.28 ± 0.58
Mesencephalon6.25 ± 0.56
Myelencephalon6.22 ± 0.55
Occipital Lobe6.18 ± 0.62
Parietal Lobe6.15 ± 0.53
Pontine Tegmentum6.08 ± 0.45
Striatum6.71 ± 0.51
Subthalamus5.72 ± 0.65
Temporal Lobe6.05 ± 0.61
Thalamus6.21 ± 0.5
White Matter5.85 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Igf2CBCerebellum7.9
9.81
Igf2CTXCerebral cortex29.63
18.07
Igf2HIPHippocampal region26.36
21.5
Igf2HPFHippocampal formation25.62
20.23
Igf2HYHypothalamus25.83
16.35
Igf2LSXLateral septal complex33.07
18.38
Igf2MBMidbrain18.81
14.92
Igf2MYMedulla8.03
9.47
Igf2OLFOlfactory bulb31.26
21.04
Igf2PPons29.54
21.28
Igf2PALPallidum29.09
18.22
Igf2RHPRetrohippocampal region24.55
18.3
Igf2sAMYStriatum-like amygdalar nuclei13.29
10.66
Igf2STRStriatum25.4
15.14
Igf2STRdStriatum dorsal region27.54
16.59
Igf2STRvStriatum ventral region20.23
10.29
Igf2THThalamus29.93
19.47
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00137404 8 113 120 FFQYDTWK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved