AutismKB 2.0

Annotation Detail for APOH


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Basic Information Top
Gene Symbol:APOH ( B2G1,BG )
Gene Full Name: apolipoprotein H (beta-2-glycoprotein I)
Band: 17q24.2
Quick LinksEntrez ID:350; OMIM: 138700; Uniprot ID:APOH_HUMAN; ENSEMBL ID: ENSG00000091583; HGNC ID: 616
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus73 / 564012129
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult176 / 193912190
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor50 / 96359518
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal471 / 3360307140
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart12 / 89626133
intestine3 / 23447212
kidney18 / 21177784
larynx0 / 241450 
liver384 / 2077431848
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle9 / 10771583
nerve0 / 157680 
ovary0 / 1020510 
pancreas47 / 214812218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205216_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.55
Adipocyte7.4
AdrenalCortex8.85
Adrenalgland6.4
Amygdala7.9
Appendix9.4
AtrioventricularNode6.4
BDCA4+_DentriticCells6.2
Bonemarrow7.7
BronchialEpithelialCells7.4
CD105+_Endothelial7.2
CD14+_Monocytes6.2
CD19+_BCells(neg._sel.)6.7
CD33+_Myeloid9
CD34+8.6
CD4+_Tcells7.65
CD56+_NKCells8
CD71+_EarlyErythroid7.05
CD8+_Tcells6.4
CardiacMyocytes13.5
Caudatenucleus6.65
Cerebellum6.1
CerebellumPeduncles8.6
CiliaryGanglion5.75
CingulateCortex7.85
Colorectaladenocarcinoma11.2
DorsalRootGanglion5.9
FetalThyroid11.55
Fetalbrain7.15
Fetalliver11931.4
Fetallung1176.55
GlobusPallidus5.45
Heart13.75
Hypothalamus7.9
Kidney10.5
Leukemia_chronicMyelogenousK-5626.7
Leukemia_promyelocytic-HL-606.5
Leukemialymphoblastic(MOLT-4)5.75
Liver12949.65
Lung9.25
Lymphnode5.9
Lymphoma_burkitts(Daudi)8.6
Lymphoma_burkitts(Raji)11.5
MedullaOblongata6.75
OccipitalLobe6.7
OlfactoryBulb5.95
Ovary7.4
Pancreas7.05
PancreaticIslet43.65
ParietalLobe8.2
Pituitary8.8
Placenta7.6
Pons7.45
PrefrontalCortex9.05
Prostate9.15
Salivarygland6.1
SkeletalMuscle10.75
Skin6.3
SmoothMuscle8.35
Spinalcord7.95
SubthalamicNucleus6.9
SuperiorCervicalGanglion17.05
TemporalLobe7.35
Testis6.4
TestisGermCell6.15
TestisIntersitial6.3
TestisLeydigCell7.6
TestisSeminiferousTubule6.9
Thalamus7.25
Thymus5.85
Thyroid9.5
Tongue7.85
Tonsil7.3
Trachea6.3
TrigeminalGanglion7.65
Uterus7
UterusCorpus6.9
WholeBlood8.2
Wholebrain6.3
colon7.5
pineal_day9.3
pineal_night8.74
retina9.675
small_intestine6.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P92325
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.05 ± 0.98
Basal Forebrain1.59 ± 0.21
Basal Part of Pons1.27 ± 0.35
Cerebellar Cortex1.41 ± 0.62
Cerebellar Nuclei2.09 ± 0.89
Claustrum2.39 ± 0.78
Epithalamus1.33 ± 0.69
Frontal Lobe1.47 ± 0.63
Globus Pallidus2.33 ± 0.69
Hypothalamus1.65 ± 0.67
Insula1.52 ± 0.52
Limbic Lobe1.62 ± 0.65
Mesencephalon1.75 ± 0.64
Myelencephalon1.62 ± 0.66
Occipital Lobe1.63 ± 0.55
Parietal Lobe1.62 ± 0.71
Pontine Tegmentum1.67 ± 0.65
Striatum1.77 ± 0.51
Subthalamus1.76 ± 0.59
Temporal Lobe1.49 ± 0.59
Thalamus1.57 ± 0.55
White Matter2.19 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
ApohCBCerebellum0
0
ApohCTXCerebral cortex0
0
ApohHIPHippocampal region0
0
ApohHPFHippocampal formation0
0
ApohHYHypothalamus0
0
ApohLSXLateral septal complex0
0
ApohMBMidbrain0
0
ApohMYMedulla0
0
ApohOLFOlfactory bulb0
0
ApohPPons0
0
ApohPALPallidum0
0
ApohRHPRetrohippocampal region0
0
ApohsAMYStriatum-like amygdalar nuclei0
0
ApohSTRStriatum0
0
ApohSTRdStriatum dorsal region0
0
ApohSTRvStriatum ventral region0
0
ApohTHThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00007696 20 39 58 TFYEPGEEITYSCKPGYVSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018