AutismKB 2.0

Annotation Detail for LCE3C


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Basic Information Top
Gene Symbol:LCE3C ( LEP15,SPRL3A )
Gene Full Name: late cornified envelope 3C
Band: 1q21.3
Quick LinksEntrez ID:353144; OMIM: 612615; Uniprot ID:LCE3C_HUMAN; ENSEMBL ID: ENSG00000186207; HGNC ID: 16612
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P405295
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.97 ± 0.74
Basal Forebrain3.21 ± 0.3
Basal Part of Pons3.18 ± 0.37
Cerebellar Cortex2.86 ± 0.52
Cerebellar Nuclei3.26 ± 0.6
Claustrum3.83 ± 0.83
Epithalamus2.86 ± 0.79
Frontal Lobe3.95 ± 0.73
Globus Pallidus2.44 ± 1.2
Hypothalamus3 ± 0.62
Insula3.95 ± 0.53
Limbic Lobe3.84 ± 0.87
Mesencephalon3.54 ± 0.73
Myelencephalon3.55 ± 0.7
Occipital Lobe3.15 ± 0.86
Parietal Lobe3.91 ± 0.68
Pontine Tegmentum3.62 ± 0.71
Striatum3.94 ± 0.71
Subthalamus3.36 ± 0.76
Temporal Lobe3.75 ± 0.74
Thalamus3.05 ± 0.77
White Matter2.03 ± 1.25
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018