AutismKB 2.0

Annotation Detail for ZNF445


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Basic Information Top
Gene Symbol:ZNF445 ( MGC126535,ZKSCAN15,ZNF168 )
Gene Full Name: zinc finger protein 445
Band: 3p21.31
Quick LinksEntrez ID:353274; OMIM: NA; Uniprot ID:ZN445_HUMAN; ENSEMBL ID: ENSG00000185219; HGNC ID: 21018
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst3 / 6231948
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor9 / 26384534
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal69 / 336030720
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain11 / 11009899
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine5 / 23447221
kidney1 / 2117774
larynx1 / 2414541
liver3 / 20774314
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate2 / 18934510
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach0 / 966190 
testis2 / 3304426
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P915355
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.56 ± 0.35
Basal Forebrain6.67 ± 0.21
Basal Part of Pons6.54 ± 0.34
Cerebellar Cortex7 ± 0.22
Cerebellar Nuclei6.4 ± 0.31
Claustrum6.91 ± 0.39
Epithalamus6.65 ± 0.27
Frontal Lobe6.51 ± 0.33
Globus Pallidus6.46 ± 0.22
Hypothalamus6.32 ± 0.34
Insula6.64 ± 0.31
Limbic Lobe6.73 ± 0.44
Mesencephalon6.66 ± 0.45
Myelencephalon6.63 ± 0.36
Occipital Lobe7.07 ± 0.36
Parietal Lobe6.7 ± 0.33
Pontine Tegmentum6.59 ± 0.37
Striatum6.26 ± 0.32
Subthalamus6.5 ± 0.39
Temporal Lobe6.58 ± 0.31
Thalamus6.62 ± 0.24
White Matter7 ± 0.14
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp445CBCerebellum100
100
Zfp445CTXCerebral cortex100
100
Zfp445HIPHippocampal region100
100
Zfp445HPFHippocampal formation100
100
Zfp445HYHypothalamus100
100
Zfp445LSXLateral septal complex100
100
Zfp445MBMidbrain100
100
Zfp445MYMedulla94.75
100
Zfp445OLFOlfactory bulb100
100
Zfp445PPons91.47
98.18
Zfp445PALPallidum100
100
Zfp445RHPRetrohippocampal region100
100
Zfp445sAMYStriatum-like amygdalar nuclei100
100
Zfp445STRStriatum100
100
Zfp445STRdStriatum dorsal region100
100
Zfp445STRvStriatum ventral region100
100
Zfp445THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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