AutismKB 2.0

Annotation Detail for IGLL1


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Basic Information Top
Gene Symbol:IGLL1 ( 14.1,AGM2,CD179b,IGL1,IGL5,IGLJ14.1,IGLL,IGO,IGVPB,VPREB2 )
Gene Full Name: immunoglobulin lambda-like polypeptide 1
Band: 22q11.23
Quick LinksEntrez ID:3543; OMIM: 146770; Uniprot ID:IGLL1_HUMAN; ENSEMBL ID: ENSG00000128322; HGNC ID: 5870
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult1 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia7 / 9584273
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal18 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood6 / 12347848
bone0 / 716550 
bone marrow9 / 48801184
brain0 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart3 / 8962633
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver3 / 20774314
lung0 / 3369740 
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206660_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.25
Adipocyte7.2
AdrenalCortex9.05
Adrenalgland6.7
Amygdala7.15
Appendix8.6
AtrioventricularNode6.25
BDCA4+_DentriticCells7.6
Bonemarrow83.05
BronchialEpithelialCells7.05
CD105+_Endothelial68.45
CD14+_Monocytes7.8
CD19+_BCells(neg._sel.)7.85
CD33+_Myeloid9.3
CD34+648.85
CD4+_Tcells7.6
CD56+_NKCells8.75
CD71+_EarlyErythroid7.1
CD8+_Tcells6.8
CardiacMyocytes13.4
Caudatenucleus6.6
Cerebellum6.1
CerebellumPeduncles8.65
CiliaryGanglion5.9
CingulateCortex7.8
Colorectaladenocarcinoma7.45
DorsalRootGanglion5.9
FetalThyroid7.35
Fetalbrain7
Fetalliver6.75
Fetallung5.45
GlobusPallidus5.95
Heart12.6
Hypothalamus7.45
Kidney6.45
Leukemia_chronicMyelogenousK-5626.55
Leukemia_promyelocytic-HL-606.65
Leukemialymphoblastic(MOLT-4)11.4
Liver12.7
Lung8.05
Lymphnode6.4
Lymphoma_burkitts(Daudi)14.15
Lymphoma_burkitts(Raji)11.75
MedullaOblongata6.45
OccipitalLobe6.55
OlfactoryBulb5.65
Ovary5.35
Pancreas6
PancreaticIslet7.95
ParietalLobe8.1
Pituitary8.8
Placenta7.1
Pons7.35
PrefrontalCortex8.75
Prostate8.65
Salivarygland6.25
SkeletalMuscle25.45
Skin5.95
SmoothMuscle8.2
Spinalcord7.75
SubthalamicNucleus6.85
SuperiorCervicalGanglion9.8
TemporalLobe6.95
Testis18.1
TestisGermCell14
TestisIntersitial17.45
TestisLeydigCell7.5
TestisSeminiferousTubule15.75
Thalamus7.6
Thymus27.35
Thyroid8.9
Tongue7.7
Tonsil7.4
Trachea6.15
TrigeminalGanglion8.9
Uterus5.95
UterusCorpus7.25
WholeBlood8.1
Wholebrain5.65
colon7.35
pineal_day8.86
pineal_night8.76
retina8.875
small_intestine7.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10936_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.08 ± 0.57
Basal Forebrain4.8 ± 0.21
Basal Part of Pons5.19 ± 0.33
Cerebellar Cortex4.72 ± 0.41
Cerebellar Nuclei4.85 ± 0.3
Claustrum5.34 ± 0.74
Epithalamus4.42 ± 0.56
Frontal Lobe4.88 ± 0.44
Globus Pallidus5.34 ± 0.38
Hypothalamus4.43 ± 0.36
Insula4.71 ± 0.35
Limbic Lobe4.94 ± 0.45
Mesencephalon4.87 ± 0.43
Myelencephalon4.91 ± 0.51
Occipital Lobe4.96 ± 0.42
Parietal Lobe4.96 ± 0.45
Pontine Tegmentum4.8 ± 0.5
Striatum4.88 ± 0.37
Subthalamus4.74 ± 0.43
Temporal Lobe4.83 ± 0.5
Thalamus5.03 ± 0.43
White Matter5.48 ± 0.21
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00045510 15 191 205 SYSCQVMHEGSTVEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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