AutismKB 2.0

Annotation Detail for IGSF1


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Basic Information Top
Gene Symbol:IGSF1 ( IGCD1,IGDC1,INHBP,KIAA0364,MGC75490,PGSF2,p120 )
Gene Full Name: immunoglobulin superfamily, member 1
Band: Xq25
Quick LinksEntrez ID:3547; OMIM: 300137; Uniprot ID:IGSF1_HUMAN; ENSEMBL ID: ENSG00000147255; HGNC ID: 5948
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst3 / 6231948
fetus39 / 56401269
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult36 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor22 / 136302161
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal113 / 336030733
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain40 / 110098936
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver5 / 20774324
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland18 / 165851085
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis40 / 330442121
thymus1 / 8113112
thyroid21 / 47473442
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207695_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.15
Adipocyte9.55
AdrenalCortex10.7
Adrenalgland11
Amygdala9.3
Appendix10.85
AtrioventricularNode12.85
BDCA4+_DentriticCells7.35
Bonemarrow10.2
BronchialEpithelialCells9.4
CD105+_Endothelial9.1
CD14+_Monocytes9.25
CD19+_BCells(neg._sel.)9.9
CD33+_Myeloid11.3
CD34+10.9
CD4+_Tcells9.35
CD56+_NKCells10.25
CD71+_EarlyErythroid8.8
CD8+_Tcells8.25
CardiacMyocytes12.9
Caudatenucleus12.6
Cerebellum8.75
CerebellumPeduncles13.75
CiliaryGanglion6.95
CingulateCortex10.8
Colorectaladenocarcinoma9.45
DorsalRootGanglion8.2
FetalThyroid9.35
Fetalbrain9.65
Fetalliver190.05
Fetallung7.75
GlobusPallidus7.45
Heart13.35
Hypothalamus35.35
Kidney8.05
Leukemia_chronicMyelogenousK-5629.8
Leukemia_promyelocytic-HL-608.55
Leukemialymphoblastic(MOLT-4)7.4
Liver13.1
Lung10.2
Lymphnode8.3
Lymphoma_burkitts(Daudi)12.3
Lymphoma_burkitts(Raji)13.85
MedullaOblongata9.75
OccipitalLobe8.35
OlfactoryBulb8.65
Ovary6.65
Pancreas7.65
PancreaticIslet10.35
ParietalLobe10.55
Pituitary877.95
Placenta9.6
Pons9.25
PrefrontalCortex11
Prostate11.2
Salivarygland9.2
SkeletalMuscle16.2
Skin10.45
SmoothMuscle10.55
Spinalcord22.55
SubthalamicNucleus8.8
SuperiorCervicalGanglion12.85
TemporalLobe8.75
Testis9.25
TestisGermCell12.9
TestisIntersitial8.15
TestisLeydigCell13.05
TestisSeminiferousTubule9.3
Thalamus17.4
Thymus7.05
Thyroid12.45
Tongue10.3
Tonsil9.45
Trachea8.15
TrigeminalGanglion13.95
Uterus8.65
UterusCorpus9.1
WholeBlood10.45
Wholebrain9.55
colon9.45
pineal_day13.56
pineal_night19.98
retina11.95
small_intestine9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12155_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.3 ± 1.02
Basal Forebrain2.8 ± 0.34
Basal Part of Pons2.05 ± 0.83
Cerebellar Cortex2.14 ± 0.51
Cerebellar Nuclei3.15 ± 0.65
Claustrum2.87 ± 0.71
Epithalamus2.36 ± 0.66
Frontal Lobe2.47 ± 0.77
Globus Pallidus4.97 ± 0.31
Hypothalamus3.33 ± 0.74
Insula2.16 ± 0.77
Limbic Lobe2.14 ± 0.77
Mesencephalon2.85 ± 0.82
Myelencephalon2.54 ± 0.73
Occipital Lobe2.57 ± 0.86
Parietal Lobe2.66 ± 0.88
Pontine Tegmentum2.78 ± 0.93
Striatum3.02 ± 0.87
Subthalamus2.83 ± 0.62
Temporal Lobe2.31 ± 0.8
Thalamus2.97 ± 0.79
White Matter3.03 ± 0.66
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Igsf1PPons0.66
0.74
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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