AutismKB 2.0

Annotation Detail for FAS


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Basic Information Top
Gene Symbol:FAS ( ALPS1A,APO-1,APT1,CD95,FAS1,FASTM,TNFRSF6 )
Gene Full Name: Fas (TNF receptor superfamily, member 6)
Band: 10q23.31
Quick LinksEntrez ID:355; OMIM: 134637; Uniprot ID:TNR6_HUMAN; ENSEMBL ID: ENSG00000026103; HGNC ID: 11920
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus13 / 56401223
neonate3 / 3109796
infant0 / 236200 
juvenile0 / 555560 
adult82 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor14 / 26384553
glioma5 / 10688346
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia8 / 9725082
normal119 / 336030735
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites0 / 400150 
bladder2 / 2975767
blood18 / 123478145
bone2 / 7165527
bone marrow2 / 4880140
brain18 / 110098916
cervix1 / 4817120
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye19 / 21105490
heart1 / 8962611
intestine5 / 23447221
kidney6 / 21177728
larynx0 / 241450 
liver5 / 20774324
lung10 / 33697429
lymph1 / 4427022
lymph node4 / 9161043
mammary gland2 / 15327113
mouth2 / 6705229
muscle3 / 10771527
nerve0 / 157680 
ovary4 / 10205139
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta9 / 28082532
prostate4 / 18934521
salivary gland0 / 201550 
skin6 / 21057428
spleen2 / 5395237
stomach3 / 9661931
testis4 / 33044212
thymus5 / 8113161
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215719_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts98
Adipocyte23
AdrenalCortex8.55
Adrenalgland6.15
Amygdala6.95
Appendix8.45
AtrioventricularNode7.4
BDCA4+_DentriticCells9.3
Bonemarrow7.65
BronchialEpithelialCells16.75
CD105+_Endothelial6.9
CD14+_Monocytes9
CD19+_BCells(neg._sel.)6.9
CD33+_Myeloid15.15
CD34+8.95
CD4+_Tcells30.4
CD56+_NKCells9.05
CD71+_EarlyErythroid21.7
CD8+_Tcells13.2
CardiacMyocytes13.9
Caudatenucleus6.15
Cerebellum5.55
CerebellumPeduncles8.25
CiliaryGanglion6.25
CingulateCortex7.1
Colorectaladenocarcinoma6.95
DorsalRootGanglion6.35
FetalThyroid6.8
Fetalbrain6.65
Fetalliver6.1
Fetallung8.35
GlobusPallidus5.5
Heart12.15
Hypothalamus7.2
Kidney6.25
Leukemia_chronicMyelogenousK-5626.1
Leukemia_promyelocytic-HL-6037.95
Leukemialymphoblastic(MOLT-4)5.35
Liver10.9
Lung7.25
Lymphnode7.15
Lymphoma_burkitts(Daudi)9.25
Lymphoma_burkitts(Raji)12.7
MedullaOblongata6.05
OccipitalLobe6.2
OlfactoryBulb5.35
Ovary8.5
Pancreas5.85
PancreaticIslet7.4
ParietalLobe7.65
Pituitary7.95
Placenta6.6
Pons6.7
PrefrontalCortex8.45
Prostate7.85
Salivarygland5.65
SkeletalMuscle10.5
Skin7.85
SmoothMuscle35.25
Spinalcord7.35
SubthalamicNucleus6.65
SuperiorCervicalGanglion11.2
TemporalLobe6.5
Testis5.9
TestisGermCell5.4
TestisIntersitial6.9
TestisLeydigCell7.4
TestisSeminiferousTubule5.85
Thalamus7.1
Thymus4.9
Thyroid8.3
Tongue7.85
Tonsil8.95
Trachea5.75
TrigeminalGanglion9.65
Uterus9.15
UterusCorpus7
WholeBlood186.7
Wholebrain5.3
colon8.4
pineal_day8.36
pineal_night8.08
retina8.325
small_intestine6.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16815_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.19 ± 0.58
Basal Forebrain4.77 ± 0.39
Basal Part of Pons4.03 ± 0.57
Cerebellar Cortex3.78 ± 0.46
Cerebellar Nuclei4.62 ± 0.47
Claustrum4.24 ± 0.72
Epithalamus5.66 ± 0.85
Frontal Lobe4.51 ± 0.61
Globus Pallidus4.79 ± 0.41
Hypothalamus4.08 ± 1.1
Insula4.3 ± 0.87
Limbic Lobe4.49 ± 0.46
Mesencephalon4.36 ± 0.79
Myelencephalon4.51 ± 0.72
Occipital Lobe4.31 ± 0.52
Parietal Lobe4.67 ± 0.6
Pontine Tegmentum4.61 ± 0.61
Striatum5.38 ± 0.34
Subthalamus4.15 ± 0.75
Temporal Lobe4.4 ± 0.54
Thalamus4.13 ± 0.52
White Matter4.06 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
FasLSXLateral septal complex3.53
2.74
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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