AutismKB 2.0

Annotation Detail for IL10RA


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Basic Information Top
Gene Symbol:IL10RA ( CDW210A,HIL-10R,IL-10R1,IL10R )
Gene Full Name: interleukin 10 receptor, alpha
Band: 11q23.3
Quick LinksEntrez ID:3587; OMIM: 146933; Uniprot ID:I10R1_HUMAN; ENSEMBL ID: ENSG00000110324; HGNC ID: 5964
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus7 / 56401212
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult60 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia10 / 95842104
liver tumor0 / 963590 
lung tumor7 / 10312767
lymphoma7 / 7175597
non-neoplasia20 / 97250205
normal94 / 336030727
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood9 / 12347872
bone1 / 7165513
bone marrow0 / 488010 
brain21 / 110098919
cervix0 / 481710 
connective tissue21 / 149255140
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart1 / 8962611
intestine4 / 23447217
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung10 / 33697429
lymph3 / 4427067
lymph node14 / 91610152
mammary gland7 / 15327145
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta11 / 28082539
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen13 / 53952240
stomach0 / 966190 
testis3 / 3304429
thymus20 / 81131246
thyroid0 / 474730 
tonsil1 / 1699958
trachea5 / 5241395
umbilical cord0 / 136800 
uterus6 / 23287825
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204912_at
Cell line Expression level Expression bar
721_B_lymphoblasts9
Adipocyte3.8
AdrenalCortex4
Adrenalgland3.25
Amygdala4.1
Appendix3.95
AtrioventricularNode2.9
BDCA4+_DentriticCells519.2
Bonemarrow14.35
BronchialEpithelialCells3.85
CD105+_Endothelial11.05
CD14+_Monocytes910.4
CD19+_BCells(neg._sel.)209.8
CD33+_Myeloid524.85
CD34+6.3
CD4+_Tcells696.95
CD56+_NKCells796.45
CD71+_EarlyErythroid3.65
CD8+_Tcells583.95
CardiacMyocytes5.1
Caudatenucleus3.45
Cerebellum3.1
CerebellumPeduncles4.35
CiliaryGanglion2.7
CingulateCortex3.95
Colorectaladenocarcinoma3.9
DorsalRootGanglion2.95
FetalThyroid3.75
Fetalbrain3.85
Fetalliver3.35
Fetallung3.25
GlobusPallidus2.8
Heart7.95
Hypothalamus4.2
Kidney3.1
Leukemia_chronicMyelogenousK-56212.45
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)3.1
Liver5
Lung23.35
Lymphnode103.75
Lymphoma_burkitts(Daudi)6.8
Lymphoma_burkitts(Raji)8.95
MedullaOblongata3.55
OccipitalLobe3.45
OlfactoryBulb3.05
Ovary2.55
Pancreas3.1
PancreaticIslet4.2
ParietalLobe4.05
Pituitary4.55
Placenta4.8
Pons3.65
PrefrontalCortex4.85
Prostate4.55
Salivarygland9.5
SkeletalMuscle4.45
Skin3
SmoothMuscle4.25
Spinalcord4.15
SubthalamicNucleus3.5
SuperiorCervicalGanglion4.95
TemporalLobe3.55
Testis3.3
TestisGermCell3.25
TestisIntersitial3.25
TestisLeydigCell3.8
TestisSeminiferousTubule3.3
Thalamus3.9
Thymus13.05
Thyroid4.9
Tongue3.8
Tonsil22.65
Trachea3.25
TrigeminalGanglion4.5
Uterus3.45
UterusCorpus3.45
WholeBlood323.85
Wholebrain3.35
colon3.9
pineal_day4.7
pineal_night4.68
retina5.05
small_intestine4.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P203173
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.49 ± 0.5
Basal Forebrain5.56 ± 0.35
Basal Part of Pons5.76 ± 0.43
Cerebellar Cortex4.59 ± 0.49
Cerebellar Nuclei6.25 ± 0.57
Claustrum5.06 ± 1.04
Epithalamus6 ± 0.63
Frontal Lobe5.38 ± 0.54
Globus Pallidus6.08 ± 0.35
Hypothalamus5.44 ± 0.94
Insula5.6 ± 0.44
Limbic Lobe5.22 ± 0.59
Mesencephalon5.23 ± 0.8
Myelencephalon5.34 ± 0.69
Occipital Lobe4.68 ± 0.75
Parietal Lobe5.33 ± 0.48
Pontine Tegmentum5.13 ± 0.65
Striatum6.33 ± 0.39
Subthalamus6.04 ± 0.16
Temporal Lobe5.41 ± 0.47
Thalamus4.88 ± 0.54
White Matter5.29 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Il10raCBCerebellum1.26
1.36
Il10raCTXCerebral cortex1.66
1.44
Il10raHIPHippocampal region0.9
0.82
Il10raHPFHippocampal formation1.14
0.74
Il10raHYHypothalamus0.73
0.59
Il10raLSXLateral septal complex0.94
0.89
Il10raMBMidbrain0.9
0.75
Il10raMYMedulla2.55
2.78
Il10raOLFOlfactory bulb1.54
0.86
Il10raPPons1.22
0.94
Il10raPALPallidum0.51
0.29
Il10raRHPRetrohippocampal region1.56
0.67
Il10rasAMYStriatum-like amygdalar nuclei1.03
0.5
Il10raSTRStriatum0.81
0.54
Il10raSTRdStriatum dorsal region0.7
0.48
Il10raSTRvStriatum ventral region0.82
0.39
Il10raTHThalamus0.77
0.7
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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