AutismKB 2.0

Annotation Detail for ACADSB


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Basic Information Top
Gene Symbol:ACADSB ( 2-MEBCAD,ACAD7,SBCAD )
Gene Full Name: acyl-CoA dehydrogenase, short/branched chain
Band: 10q26.13
Quick LinksEntrez ID:36; OMIM: 600301; Uniprot ID:ACDSB_HUMAN; ENSEMBL ID: ENSG00000196177; HGNC ID: 91
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus56 / 56401299
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult74 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor4 / 13630229
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor8 / 9635983
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal158 / 336030747
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer9 / 10268087
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites1 / 4001524
bladder3 / 29757100
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain18 / 110098916
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye5 / 21105423
heart1 / 8962611
intestine10 / 23447242
kidney33 / 211777155
larynx0 / 241450 
liver29 / 207743139
lung13 / 33697438
lymph0 / 442700 
lymph node2 / 9161021
mammary gland13 / 15327184
mouth1 / 6705214
muscle5 / 10771546
nerve0 / 157680 
ovary3 / 10205129
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta1 / 2808253
prostate14 / 18934573
salivary gland0 / 201550 
skin7 / 21057433
spleen1 / 5395218
stomach2 / 9661920
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205355_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.9
Adipocyte13
AdrenalCortex23.35
Adrenalgland12
Amygdala12.7
Appendix25.45
AtrioventricularNode26.65
BDCA4+_DentriticCells11.2
Bonemarrow13.95
BronchialEpithelialCells13.2
CD105+_Endothelial32.55
CD14+_Monocytes14.7
CD19+_BCells(neg._sel.)15.5
CD33+_Myeloid18.25
CD34+15.85
CD4+_Tcells14.15
CD56+_NKCells15.2
CD71+_EarlyErythroid12.85
CD8+_Tcells11.65
CardiacMyocytes30.9
Caudatenucleus11.25
Cerebellum10.25
CerebellumPeduncles20.75
CiliaryGanglion21.65
CingulateCortex15.9
Colorectaladenocarcinoma11.85
DorsalRootGanglion20.35
FetalThyroid13.5
Fetalbrain12.5
Fetalliver224.35
Fetallung10.4
GlobusPallidus13.1
Heart25.95
Hypothalamus13.5
Kidney13.7
Leukemia_chronicMyelogenousK-56213.8
Leukemia_promyelocytic-HL-6012.1
Leukemialymphoblastic(MOLT-4)10.05
Liver22.6
Lung13.5
Lymphnode9.65
Lymphoma_burkitts(Daudi)17.6
Lymphoma_burkitts(Raji)20.5
MedullaOblongata11.55
OccipitalLobe11.5
OlfactoryBulb10.35
Ovary12.9
Pancreas12.9
PancreaticIslet24.5
ParietalLobe15.05
Pituitary16.6
Placenta10.95
Pons17.5
PrefrontalCortex14.25
Prostate26.1
Salivarygland14.1
SkeletalMuscle31.35
Skin20.55
SmoothMuscle14.55
Spinalcord13.7
SubthalamicNucleus16.3
SuperiorCervicalGanglion29.75
TemporalLobe13.1
Testis11.45
TestisGermCell14.1
TestisIntersitial15.65
TestisLeydigCell14.7
TestisSeminiferousTubule12.05
Thalamus13.35
Thymus8.25
Thyroid15.75
Tongue21.3
Tonsil13.55
Trachea10.85
TrigeminalGanglion79.5
Uterus10
UterusCorpus19.2
WholeBlood12.9
Wholebrain7.75
colon17.5
pineal_day18.44
pineal_night16.14
retina15.65
small_intestine17.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P31945
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.25 ± 0.2
Basal Forebrain7.21 ± 0.17
Basal Part of Pons7.11 ± 0.23
Cerebellar Cortex7.11 ± 0.3
Cerebellar Nuclei7.36 ± 0.23
Claustrum6.87 ± 0.26
Epithalamus7.12 ± 0.28
Frontal Lobe7.18 ± 0.25
Globus Pallidus7.42 ± 0.26
Hypothalamus7.17 ± 0.19
Insula7.13 ± 0.13
Limbic Lobe7.23 ± 0.29
Mesencephalon7.22 ± 0.35
Myelencephalon7.2 ± 0.27
Occipital Lobe7.57 ± 0.23
Parietal Lobe7.24 ± 0.25
Pontine Tegmentum7.27 ± 0.3
Striatum7.46 ± 0.21
Subthalamus7.32 ± 0.22
Temporal Lobe7.15 ± 0.25
Thalamus7.36 ± 0.21
White Matter7.29 ± 0.03
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AcadsbCBCerebellum0.62
1.69
AcadsbCTXCerebral cortex0.19
0.3
AcadsbHIPHippocampal region1.01
1.78
AcadsbHPFHippocampal formation0.76
1.19
AcadsbHYHypothalamus0.49
0.53
AcadsbLSXLateral septal complex0.32
0.56
AcadsbMBMidbrain0.06
0.08
AcadsbMYMedulla0.52
0.87
AcadsbOLFOlfactory bulb0.45
0.52
AcadsbPPons0.21
0.39
AcadsbPALPallidum0.09
0.06
AcadsbRHPRetrohippocampal region0.37
0.4
AcadsbsAMYStriatum-like amygdalar nuclei0.37
0.4
AcadsbSTRStriatum0.11
0.13
AcadsbSTRdStriatum dorsal region0.05
0.05
AcadsbSTRvStriatum ventral region0.08
0.09
AcadsbTHThalamus0.1
0.1
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ACDSB_HUMAN_230 22 230 251 GITSFLVDRDTPGLHIGKPENK PRIDE
ACDSB_HUMAN_325 22 325 346 LFDFQGLQHQVAHVATQLEAAR PRIDE
PAp00000709 28 257 284 ASSTCPLTFENVKVPEANILGQIGHGYK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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