AutismKB 2.0

Annotation Detail for FOXK2


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Basic Information Top
Gene Symbol:FOXK2 ( ILF,ILF-1,ILF1 )
Gene Full Name: forkhead box K2
Band: 17q25.3
Quick LinksEntrez ID:3607; OMIM: 147685; Uniprot ID:FOXK2_HUMAN; ENSEMBL ID: ENSG00000141568; HGNC ID: 6036
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst9 / 62319144
fetus56 / 56401299
neonate1 / 3109732
infant2 / 2362084
juvenile2 / 5555635
adult167 / 193912186
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor10 / 94178106
cervical tumor2 / 3436658
chondrosarcoma16 / 82823193
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor13 / 26384549
glioma23 / 106883215
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia12 / 95842125
liver tumor13 / 96359134
lung tumor10 / 10312796
lymphoma3 / 7175541
non-neoplasia3 / 9725030
normal230 / 336030768
ovarian tumor5 / 7668265
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer4 / 10268038
retinoblastoma2 / 4635643
skin tumor6 / 12494948
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood11 / 12347889
bone16 / 71655223
bone marrow2 / 4880140
brain74 / 110098967
cervix5 / 48171103
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue20 / 21572292
esophagus0 / 202090 
eye34 / 211054161
heart12 / 89626133
intestine22 / 23447293
kidney3 / 21177714
larynx0 / 241450 
liver18 / 20774386
lung45 / 336974133
lymph2 / 4427045
lymph node14 / 91610152
mammary gland14 / 15327191
mouth2 / 6705229
muscle6 / 10771555
nerve0 / 157680 
ovary5 / 10205148
pancreas10 / 21481246
parathyroid5 / 20539243
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta16 / 28082556
prostate13 / 18934568
salivary gland0 / 201550 
skin9 / 21057442
spleen1 / 5395218
stomach4 / 9661941
testis7 / 33044221
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus15 / 23287864
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203064_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts105.75
Adipocyte12.9
AdrenalCortex179.25
Adrenalgland30.05
Amygdala20.3
Appendix11.7
AtrioventricularNode8.2
BDCA4+_DentriticCells28.2
Bonemarrow21.5
BronchialEpithelialCells47.15
CD105+_Endothelial31.95
CD14+_Monocytes23.6
CD19+_BCells(neg._sel.)29.7
CD33+_Myeloid35.45
CD34+34.55
CD4+_Tcells18.15
CD56+_NKCells33.45
CD71+_EarlyErythroid12.7
CD8+_Tcells19.9
CardiacMyocytes16.35
Caudatenucleus12.3
Cerebellum12.15
CerebellumPeduncles16.65
CiliaryGanglion8.45
CingulateCortex15.25
Colorectaladenocarcinoma31.75
DorsalRootGanglion10.2
FetalThyroid13.85
Fetalbrain13.3
Fetalliver11.3
Fetallung17.35
GlobusPallidus7.85
Heart24.85
Hypothalamus15.8
Kidney12.45
Leukemia_chronicMyelogenousK-56223.2
Leukemia_promyelocytic-HL-6036.35
Leukemialymphoblastic(MOLT-4)52.7
Liver19.65
Lung30.15
Lymphnode11.5
Lymphoma_burkitts(Daudi)45.7
Lymphoma_burkitts(Raji)74.35
MedullaOblongata15.15
OccipitalLobe17.05
OlfactoryBulb14.95
Ovary8.65
Pancreas11.65
PancreaticIslet14.2
ParietalLobe14.5
Pituitary17.05
Placenta27.65
Pons11.9
PrefrontalCortex19.85
Prostate26.25
Salivarygland10.55
SkeletalMuscle15.25
Skin10.25
SmoothMuscle17.05
Spinalcord11.5
SubthalamicNucleus12
SuperiorCervicalGanglion15.3
TemporalLobe15.6
Testis52.2
TestisGermCell40.45
TestisIntersitial18
TestisLeydigCell16.1
TestisSeminiferousTubule28.55
Thalamus14.65
Thymus13.45
Thyroid21.6
Tongue14.6
Tonsil14.25
Trachea10.35
TrigeminalGanglion7.45
Uterus24.3
UterusCorpus12.95
WholeBlood14.7
Wholebrain28.65
colon13.7
pineal_day19.32
pineal_night18.6
retina17.6
small_intestine13.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P416301
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.71 ± 0.41
Basal Forebrain7.26 ± 0.13
Basal Part of Pons7.21 ± 0.26
Cerebellar Cortex7.22 ± 0.35
Cerebellar Nuclei7.09 ± 0.21
Claustrum7.92 ± 0.56
Epithalamus6.97 ± 0.29
Frontal Lobe7.19 ± 0.36
Globus Pallidus6.92 ± 0.24
Hypothalamus6.92 ± 0.28
Insula7.17 ± 0.4
Limbic Lobe7.64 ± 0.48
Mesencephalon7.25 ± 0.34
Myelencephalon7.35 ± 0.4
Occipital Lobe7.8 ± 0.54
Parietal Lobe7.35 ± 0.37
Pontine Tegmentum7.31 ± 0.39
Striatum7.55 ± 0.44
Subthalamus6.67 ± 0.23
Temporal Lobe7.33 ± 0.34
Thalamus7.38 ± 0.34
White Matter7.3 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Foxk2CBCerebellum23.1
37.54
Foxk2CTXCerebral cortex17.71
13.05
Foxk2HIPHippocampal region13.95
14.5
Foxk2HPFHippocampal formation15.38
14.33
Foxk2HYHypothalamus1.21
0.97
Foxk2LSXLateral septal complex2.65
1.93
Foxk2MBMidbrain2.93
2.89
Foxk2MYMedulla6.47
7.18
Foxk2OLFOlfactory bulb14.74
11.08
Foxk2PPons3.56
3.88
Foxk2PALPallidum0.99
0.97
Foxk2RHPRetrohippocampal region18.2
14.4
Foxk2sAMYStriatum-like amygdalar nuclei3.5
2.54
Foxk2STRStriatum3.87
2.94
Foxk2STRdStriatum dorsal region4.14
3.26
Foxk2STRvStriatum ventral region3.75
2.56
Foxk2THThalamus3.36
3.06
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00503157 21 421 441 FAQSAPGSPLSSQPVLITVQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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