AutismKB 2.0

Annotation Detail for ILF2


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Basic Information Top
Gene Symbol:ILF2 ( MGC8391,NF45,PRO3063 )
Gene Full Name: interleukin enhancer binding factor 2, 45kDa
Band: 1q21.3
Quick LinksEntrez ID:3608; OMIM: 603181; Uniprot ID:ILF2_HUMAN; ENSEMBL ID: ENSG00000143621; HGNC ID: 6037
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body29 / 70761409
blastocyst26 / 62319417
fetus147 / 564012260
neonate3 / 3109796
infant16 / 23620677
juvenile19 / 55556341
adult376 / 1939121193
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200052_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts668.15
Adipocyte62.4
AdrenalCortex42.2
Adrenalgland55.75
Amygdala36.25
Appendix29
AtrioventricularNode27.35
BDCA4+_DentriticCells364.35
Bonemarrow82.55
BronchialEpithelialCells237
CD105+_Endothelial485.15
CD14+_Monocytes153.5
CD19+_BCells(neg._sel.)227.55
CD33+_Myeloid207.1
CD34+603.1
CD4+_Tcells150.9
CD56+_NKCells199.2
CD71+_EarlyErythroid205.35
CD8+_Tcells144.8
CardiacMyocytes171
Caudatenucleus29.2
Cerebellum25.95
CerebellumPeduncles36.55
CiliaryGanglion25.3
CingulateCortex34.35
Colorectaladenocarcinoma54.65
DorsalRootGanglion27.9
FetalThyroid46.45
Fetalbrain96.4
Fetalliver74.45
Fetallung98.35
GlobusPallidus35.55
Heart22.85
Hypothalamus87.9
Kidney60.45
Leukemia_chronicMyelogenousK-562196.3
Leukemia_promyelocytic-HL-60147.8
Leukemialymphoblastic(MOLT-4)281.4
Liver25.7
Lung30.25
Lymphnode58
Lymphoma_burkitts(Daudi)302.5
Lymphoma_burkitts(Raji)59.5
MedullaOblongata28.1
OccipitalLobe45.05
OlfactoryBulb30.8
Ovary27.95
Pancreas51.8
PancreaticIslet127.25
ParietalLobe23.8
Pituitary98.5
Placenta108.15
Pons29.9
PrefrontalCortex45.95
Prostate38.85
Salivarygland64.75
SkeletalMuscle26.2
Skin38.05
SmoothMuscle183.3
Spinalcord49.55
SubthalamicNucleus32.4
SuperiorCervicalGanglion24.9
TemporalLobe24.8
Testis164.2
TestisGermCell129.05
TestisIntersitial144.95
TestisLeydigCell100.6
TestisSeminiferousTubule114.7
Thalamus45.25
Thymus196.75
Thyroid66.1
Tongue33.15
Tonsil95.65
Trachea44.6
TrigeminalGanglion27.05
Uterus41.45
UterusCorpus26.15
WholeBlood59.55
Wholebrain41.1
colon96.65
pineal_day105.74
pineal_night111.06
retina101.25
small_intestine142.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6138_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.9 ± 0.65
Basal Forebrain5.18 ± 0.29
Basal Part of Pons5.22 ± 0.65
Cerebellar Cortex5.57 ± 0.27
Cerebellar Nuclei5.15 ± 0.43
Claustrum4.72 ± 0.73
Epithalamus5.31 ± 0.38
Frontal Lobe5.27 ± 0.48
Globus Pallidus5.05 ± 0.29
Hypothalamus5.25 ± 0.56
Insula5.36 ± 0.29
Limbic Lobe5.01 ± 0.58
Mesencephalon5.2 ± 0.5
Myelencephalon5.21 ± 0.51
Occipital Lobe4.92 ± 0.68
Parietal Lobe5.1 ± 0.44
Pontine Tegmentum5.11 ± 0.56
Striatum4.77 ± 0.39
Subthalamus4.82 ± 0.55
Temporal Lobe5.27 ± 0.44
Thalamus5.25 ± 0.5
White Matter5.84 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ilf2CBCerebellum74.83
100
Ilf2CTXCerebral cortex100
100
Ilf2HIPHippocampal region100
100
Ilf2HPFHippocampal formation100
100
Ilf2HYHypothalamus89.67
97.49
Ilf2LSXLateral septal complex61.12
64.69
Ilf2MBMidbrain44.87
52.34
Ilf2MYMedulla59.27
94.27
Ilf2OLFOlfactory bulb100
100
Ilf2PPons54.58
78.36
Ilf2PALPallidum77.74
93.92
Ilf2RHPRetrohippocampal region100
100
Ilf2sAMYStriatum-like amygdalar nuclei100
100
Ilf2STRStriatum100
100
Ilf2STRdStriatum dorsal region100
100
Ilf2STRvStriatum ventral region100
100
Ilf2THThalamus63.74
73.87
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ILF2_HUMAN_128 14 128 141 ILPTLEAVAALGNK PRIDE
ILF2_HUMAN_25 19 25 43 PFVPHIPFDFYLCEMAFPR PRIDE
ILF2_HUMAN_260 10 260 269 QPLALNVAYR PRIDE
PAp00034945 14 128 141 ILPTLEAVAALGNK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018