AutismKB 2.0

Annotation Detail for INPP1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:INPP1 ( MGC110984 )
Gene Full Name: inositol polyphosphate-1-phosphatase
Band: 2q32.2
Quick LinksEntrez ID:3628; OMIM: 147263; Uniprot ID:INPP_HUMAN; ENSEMBL ID: ENSG00000151689; HGNC ID: 6071
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult96 / 193912149
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor10 / 11424687
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor5 / 26384518
glioma6 / 10688356
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor4 / 9635941
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal133 / 336030739
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain70 / 110098963
cervix3 / 4817162
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye13 / 21105461
heart3 / 8962633
intestine16 / 23447268
kidney8 / 21177737
larynx4 / 24145165
liver7 / 20774333
lung22 / 33697465
lymph0 / 442700 
lymph node4 / 9161043
mammary gland2 / 15327113
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta3 / 28082510
prostate6 / 18934531
salivary gland1 / 2015549
skin1 / 2105744
spleen1 / 5395218
stomach6 / 9661962
testis29 / 33044287
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202794_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.8
Adipocyte13.4
AdrenalCortex54.5
Adrenalgland54.6
Amygdala180.55
Appendix18.75
AtrioventricularNode6.4
BDCA4+_DentriticCells12.6
Bonemarrow9.4
BronchialEpithelialCells27.45
CD105+_Endothelial7.65
CD14+_Monocytes62.55
CD19+_BCells(neg._sel.)16.25
CD33+_Myeloid66.5
CD34+23.25
CD4+_Tcells16.7
CD56+_NKCells71.2
CD71+_EarlyErythroid7.2
CD8+_Tcells21.45
CardiacMyocytes13.15
Caudatenucleus94.75
Cerebellum40.2
CerebellumPeduncles45.5
CiliaryGanglion10.2
CingulateCortex114.7
Colorectaladenocarcinoma29.75
DorsalRootGanglion10.15
FetalThyroid14.05
Fetalbrain55.6
Fetalliver17.05
Fetallung85.8
GlobusPallidus50.3
Heart10.5
Hypothalamus306.35
Kidney7.15
Leukemia_chronicMyelogenousK-56271.55
Leukemia_promyelocytic-HL-606.7
Leukemialymphoblastic(MOLT-4)6.85
Liver15.75
Lung138.85
Lymphnode13.75
Lymphoma_burkitts(Daudi)9.75
Lymphoma_burkitts(Raji)13.1
MedullaOblongata75.9
OccipitalLobe134.8
OlfactoryBulb88.4
Ovary7.45
Pancreas33.5
PancreaticIslet49.2
ParietalLobe63.3
Pituitary70.05
Placenta14.05
Pons40.25
PrefrontalCortex208.95
Prostate17.1
Salivarygland9.55
SkeletalMuscle9.85
Skin17.45
SmoothMuscle10.9
Spinalcord117.35
SubthalamicNucleus46.15
SuperiorCervicalGanglion10.85
TemporalLobe26.95
Testis294.9
TestisGermCell317.15
TestisIntersitial589.55
TestisLeydigCell209.3
TestisSeminiferousTubule237.55
Thalamus126.9
Thymus40.95
Thyroid45.1
Tongue28.8
Tonsil30.45
Trachea15.05
TrigeminalGanglion9.85
Uterus33.4
UterusCorpus9.95
WholeBlood10.55
Wholebrain175.2
colon16.3
pineal_day32.46
pineal_night51.5
retina132.7
small_intestine51.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P44453
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.79 ± 0.52
Basal Forebrain5.25 ± 0.25
Basal Part of Pons5.31 ± 0.46
Cerebellar Cortex5.18 ± 0.36
Cerebellar Nuclei5 ± 0.42
Claustrum4.63 ± 0.81
Epithalamus4.98 ± 0.62
Frontal Lobe5.19 ± 0.46
Globus Pallidus5.62 ± 0.27
Hypothalamus5.01 ± 0.55
Insula5.11 ± 0.25
Limbic Lobe4.95 ± 0.41
Mesencephalon5.01 ± 0.6
Myelencephalon5.03 ± 0.5
Occipital Lobe4.86 ± 0.39
Parietal Lobe5.02 ± 0.38
Pontine Tegmentum5.08 ± 0.37
Striatum4.97 ± 0.37
Subthalamus4.96 ± 0.06
Temporal Lobe5.07 ± 0.43
Thalamus5.1 ± 0.47
White Matter6.8 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Inpp1CBCerebellum26.61
87.34
Inpp1CTXCerebral cortex79.35
69.29
Inpp1HIPHippocampal region47.55
77.26
Inpp1HPFHippocampal formation55.75
75.82
Inpp1HYHypothalamus40.8
40.04
Inpp1LSXLateral septal complex60.3
56.85
Inpp1MBMidbrain41.03
45
Inpp1MYMedulla33.32
49.1
Inpp1OLFOlfactory bulb80.15
75.37
Inpp1PPons31.3
44.18
Inpp1PALPallidum44.46
43.92
Inpp1RHPRetrohippocampal region70.15
67.22
Inpp1sAMYStriatum-like amygdalar nuclei60.64
49.06
Inpp1STRStriatum52.14
42.49
Inpp1STRdStriatum dorsal region43.89
34.33
Inpp1STRvStriatum ventral region65.98
54.73
Inpp1THThalamus74.23
73.43
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
INPP_HUMAN_24 9 24 32 QQEALFQLL PRIDE
PAp00096342 14 96 109 LCSTEEETAELLSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved