AutismKB 2.0

Annotation Detail for INPP5B


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Basic Information Top
Gene Symbol:INPP5B ( 5PTase,MGC65156,MGC71303 )
Gene Full Name: inositol polyphosphate-5-phosphatase, 75kDa
Band: 1p34.3
Quick LinksEntrez ID:3633; OMIM: 147264; Uniprot ID:I5P2_HUMAN; ENSEMBL ID: ENSG00000204084; HGNC ID: 6077
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult38 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor14 / 26384553
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma7 / 7175597
non-neoplasia0 / 972500 
normal68 / 336030720
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain22 / 110098919
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye4 / 21105418
heart2 / 8962622
intestine5 / 23447221
kidney4 / 21177718
larynx1 / 2414541
liver3 / 20774314
lung7 / 33697420
lymph4 / 4427090
lymph node11 / 91610120
mammary gland1 / 1532716
mouth1 / 6705214
muscle5 / 10771546
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate3 / 18934515
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis14 / 33044242
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213643_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts21.95
Adipocyte4.7
AdrenalCortex5.15
Adrenalgland4.1
Amygdala4.95
Appendix5.15
AtrioventricularNode3.9
BDCA4+_DentriticCells6.5
Bonemarrow5.2
BronchialEpithelialCells4.65
CD105+_Endothelial4.85
CD14+_Monocytes5.2
CD19+_BCells(neg._sel.)5.15
CD33+_Myeloid6.2
CD34+6.15
CD4+_Tcells5.3
CD56+_NKCells6.25
CD71+_EarlyErythroid12.5
CD8+_Tcells4.65
CardiacMyocytes6.65
Caudatenucleus4.25
Cerebellum3.9
CerebellumPeduncles5.6
CiliaryGanglion4.2
CingulateCortex4.9
Colorectaladenocarcinoma4.8
DorsalRootGanglion3.8
FetalThyroid4.65
Fetalbrain4.55
Fetalliver4.25
Fetallung3.95
GlobusPallidus3.5
Heart7.35
Hypothalamus5.1
Kidney4
Leukemia_chronicMyelogenousK-5624.3
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.85
Liver6.55
Lung5.35
Lymphnode4.2
Lymphoma_burkitts(Daudi)6.35
Lymphoma_burkitts(Raji)6.9
MedullaOblongata4.35
OccipitalLobe4.25
OlfactoryBulb3.75
Ovary3.15
Pancreas3.85
PancreaticIslet5.1
ParietalLobe5.15
Pituitary5.6
Placenta5.05
Pons4.6
PrefrontalCortex5.75
Prostate5.4
Salivarygland3.95
SkeletalMuscle5.9
Skin3.85
SmoothMuscle5.5
Spinalcord5
SubthalamicNucleus4.35
SuperiorCervicalGanglion5.7
TemporalLobe4.4
Testis4.15
TestisGermCell3.9
TestisIntersitial4
TestisLeydigCell4.75
TestisSeminiferousTubule4.1
Thalamus4.9
Thymus3.75
Thyroid6.05
Tongue4.65
Tonsil4.7
Trachea4.05
TrigeminalGanglion4.95
Uterus4
UterusCorpus4.35
WholeBlood5.5
Wholebrain3.9
colon4.85
pineal_day5.84
pineal_night5.76
retina5.9
small_intestine4.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P332806
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.86 ± 0.84
Basal Forebrain3.31 ± 0.41
Basal Part of Pons3.25 ± 0.35
Cerebellar Cortex4.05 ± 0.39
Cerebellar Nuclei3.78 ± 0.34
Claustrum4 ± 0.78
Epithalamus3.74 ± 0.58
Frontal Lobe3.4 ± 0.68
Globus Pallidus3.75 ± 0.55
Hypothalamus3.4 ± 0.5
Insula3.51 ± 0.5
Limbic Lobe3.55 ± 0.65
Mesencephalon3.71 ± 0.77
Myelencephalon3.55 ± 0.67
Occipital Lobe4.14 ± 0.64
Parietal Lobe3.61 ± 0.61
Pontine Tegmentum3.62 ± 0.65
Striatum3.16 ± 0.68
Subthalamus3.1 ± 0.52
Temporal Lobe3.47 ± 0.64
Thalamus3.62 ± 0.52
White Matter4.94 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Inpp5bCBCerebellum100
100
Inpp5bCTXCerebral cortex100
100
Inpp5bHIPHippocampal region100
100
Inpp5bHPFHippocampal formation100
100
Inpp5bHYHypothalamus100
100
Inpp5bLSXLateral septal complex100
100
Inpp5bMBMidbrain100
100
Inpp5bMYMedulla100
100
Inpp5bOLFOlfactory bulb100
100
Inpp5bPPons94.16
100
Inpp5bPALPallidum100
100
Inpp5bRHPRetrohippocampal region100
100
Inpp5bsAMYStriatum-like amygdalar nuclei100
100
Inpp5bSTRStriatum100
100
Inpp5bSTRdStriatum dorsal region100
99.22
Inpp5bSTRvStriatum ventral region100
100
Inpp5bTHThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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