AutismKB 2.0

Annotation Detail for INPP5B


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Basic Information Top
Gene Symbol:INPP5B ( 5PTase,MGC65156,MGC71303 )
Gene Full Name: inositol polyphosphate-5-phosphatase, 75kDa
Band: 1p34.3
Quick LinksEntrez ID:3633; OMIM: 147264; Uniprot ID:I5P2_HUMAN; ENSEMBL ID: ENSG00000204084; HGNC ID: 6077
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult38 / 193912119
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213643_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts21.95
Adipocyte4.7
AdrenalCortex5.15
Adrenalgland4.1
Amygdala4.95
Appendix5.15
AtrioventricularNode3.9
BDCA4+_DentriticCells6.5
Bonemarrow5.2
BronchialEpithelialCells4.65
CD105+_Endothelial4.85
CD14+_Monocytes5.2
CD19+_BCells(neg._sel.)5.15
CD33+_Myeloid6.2
CD34+6.15
CD4+_Tcells5.3
CD56+_NKCells6.25
CD71+_EarlyErythroid12.5
CD8+_Tcells4.65
CardiacMyocytes6.65
Caudatenucleus4.25
Cerebellum3.9
CerebellumPeduncles5.6
CiliaryGanglion4.2
CingulateCortex4.9
Colorectaladenocarcinoma4.8
DorsalRootGanglion3.8
FetalThyroid4.65
Fetalbrain4.55
Fetalliver4.25
Fetallung3.95
GlobusPallidus3.5
Heart7.35
Hypothalamus5.1
Kidney4
Leukemia_chronicMyelogenousK-5624.3
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.85
Liver6.55
Lung5.35
Lymphnode4.2
Lymphoma_burkitts(Daudi)6.35
Lymphoma_burkitts(Raji)6.9
MedullaOblongata4.35
OccipitalLobe4.25
OlfactoryBulb3.75
Ovary3.15
Pancreas3.85
PancreaticIslet5.1
ParietalLobe5.15
Pituitary5.6
Placenta5.05
Pons4.6
PrefrontalCortex5.75
Prostate5.4
Salivarygland3.95
SkeletalMuscle5.9
Skin3.85
SmoothMuscle5.5
Spinalcord5
SubthalamicNucleus4.35
SuperiorCervicalGanglion5.7
TemporalLobe4.4
Testis4.15
TestisGermCell3.9
TestisIntersitial4
TestisLeydigCell4.75
TestisSeminiferousTubule4.1
Thalamus4.9
Thymus3.75
Thyroid6.05
Tongue4.65
Tonsil4.7
Trachea4.05
TrigeminalGanglion4.95
Uterus4
UterusCorpus4.35
WholeBlood5.5
Wholebrain3.9
colon4.85
pineal_day5.84
pineal_night5.76
retina5.9
small_intestine4.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P332806
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.86 ± 0.84
Basal Forebrain3.31 ± 0.41
Basal Part of Pons3.25 ± 0.35
Cerebellar Cortex4.05 ± 0.39
Cerebellar Nuclei3.78 ± 0.34
Claustrum4 ± 0.78
Epithalamus3.74 ± 0.58
Frontal Lobe3.4 ± 0.68
Globus Pallidus3.75 ± 0.55
Hypothalamus3.4 ± 0.5
Insula3.51 ± 0.5
Limbic Lobe3.55 ± 0.65
Mesencephalon3.71 ± 0.77
Myelencephalon3.55 ± 0.67
Occipital Lobe4.14 ± 0.64
Parietal Lobe3.61 ± 0.61
Pontine Tegmentum3.62 ± 0.65
Striatum3.16 ± 0.68
Subthalamus3.1 ± 0.52
Temporal Lobe3.47 ± 0.64
Thalamus3.62 ± 0.52
White Matter4.94 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Inpp5bCBCerebellum100
100
Inpp5bCTXCerebral cortex100
100
Inpp5bHIPHippocampal region100
100
Inpp5bHPFHippocampal formation100
100
Inpp5bHYHypothalamus100
100
Inpp5bLSXLateral septal complex100
100
Inpp5bMBMidbrain100
100
Inpp5bMYMedulla100
100
Inpp5bOLFOlfactory bulb100
100
Inpp5bPPons94.16
100
Inpp5bPALPallidum100
100
Inpp5bRHPRetrohippocampal region100
100
Inpp5bsAMYStriatum-like amygdalar nuclei100
100
Inpp5bSTRStriatum100
100
Inpp5bSTRdStriatum dorsal region100
99.22
Inpp5bSTRvStriatum ventral region100
100
Inpp5bTHThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018