Annotation Detail for INPP5D
Basic Information Top
| Gene Symbol: | INPP5D ( MGC104855,MGC142140,MGC142142,SHIP,SHIP1,SIP-145,hp51CN ) |
|---|---|
| Gene Full Name: | inositol polyphosphate-5-phosphatase, 145kDa |
| Band: | 2q37.1 |
| Quick Links | Entrez ID:3635; OMIM: 601582; Uniprot ID:SHIP1_HUMAN; ENSEMBL ID: ENSG00000168918; HGNC ID: 6079 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.601911
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 27 / 564012 | 47 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 69 / 1939121 | 35 | |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 3 / 564012 | 5 |  |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 15 / 1939121 | 7 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 8 / 114246 | 70 |  |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 6 / 263845 | 22 | |
| glioma | 12 / 106883 | 112 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 44 / 95842 | 459 |  |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 5 / 71755 | 69 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 269 / 3360307 | 80 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 2 / 90257 | 22 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 7 / 263845 | 26 | |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 14 / 95842 | 146 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 10 / 71755 | 139 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 78 / 3360307 | 23 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 13 / 123478 | 105 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 12 / 48801 | 245 | |
| brain | 18 / 1100989 | 16 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 9 / 211054 | 42 | |
| heart | 4 / 89626 | 44 | |
| intestine | 19 / 234472 | 81 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 14 / 336974 | 41 | |
| lymph | 2 / 44270 | 45 | |
| lymph node | 189 / 91610 | 2063 |  |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 2 / 214812 | 9 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 2 / 41328 | 48 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 8 / 280825 | 28 | |
| prostate | 4 / 189345 | 21 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 0 / 96619 | 0 | |
| testis | 3 / 330442 | 9 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 14 / 16999 | 823 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 6 / 232878 | 25 | |
| vascular | 1 / 51780 | 19 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 9 / 123478 | 72 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 18 / 48801 | 368 | |
| brain | 4 / 1100989 | 3 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 1 / 89626 | 11 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 9 / 44270 | 203 | |
| lymph node | 61 / 91610 | 665 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 4 / 53952 | 74 | |
| stomach | 1 / 96619 | 10 | |
| testis | 0 / 330442 | 0 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 203331_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 36.65 | |
| Adipocyte | 4.05 | |
| AdrenalCortex | 4.3 | |
| Adrenalgland | 3.4 | |
| Amygdala | 4.2 | |
| Appendix | 4.5 | |
| AtrioventricularNode | 3.1 | |
| BDCA4+_DentriticCells | 15.05 | |
| Bonemarrow | 6.9 | |
| BronchialEpithelialCells | 4.3 | |
| CD105+_Endothelial | 4.15 | |
| CD14+_Monocytes | 5.9 | |
| CD19+_BCells(neg._sel.) | 26.75 | |
| CD33+_Myeloid | 6.4 | |
| CD34+ | 7.2 | |
| CD4+_Tcells | 13.45 | |
| CD56+_NKCells | 56.3 | |
| CD71+_EarlyErythroid | 3.9 | |
| CD8+_Tcells | 40.9 | |
| CardiacMyocytes | 5.35 | |
| Caudatenucleus | 3.7 | |
| Cerebellum | 3.3 | |
| CerebellumPeduncles | 4.7 | |
| CiliaryGanglion | 3.05 | |
| CingulateCortex | 4.2 | |
| Colorectaladenocarcinoma | 4.1 | |
| DorsalRootGanglion | 3.2 | |
| FetalThyroid | 3.95 | |
| Fetalbrain | 4.05 | |
| Fetalliver | 3.55 | |
| Fetallung | 3.2 | |
| GlobusPallidus | 2.95 | |
| Heart | 5.3 | |
| Hypothalamus | 4.4 | |
| Kidney | 3.35 | |
| Leukemia_chronicMyelogenousK-562 | 3.7 | |
| Leukemia_promyelocytic-HL-60 | 3.65 | |
| Leukemialymphoblastic(MOLT-4) | 3.75 | |
| Liver | 5.35 | |
| Lung | 5.9 | |
| Lymphnode | 10.75 | |
| Lymphoma_burkitts(Daudi) | 5.3 | |
| Lymphoma_burkitts(Raji) | 13.65 | |
| MedullaOblongata | 3.7 | |
| OccipitalLobe | 3.7 | |
| OlfactoryBulb | 3.3 | |
| Ovary | 2.85 | |
| Pancreas | 3.35 | |
| PancreaticIslet | 4.35 | |
| ParietalLobe | 4.35 | |
| Pituitary | 4.75 | |
| Placenta | 4.3 | |
| Pons | 3.9 | |
| PrefrontalCortex | 5.1 | |
| Prostate | 4.8 | |
| Salivarygland | 3.3 | |
| SkeletalMuscle | 4.85 | |
| Skin | 3.1 | |
| SmoothMuscle | 4.6 | |
| Spinalcord | 4.4 | |
| SubthalamicNucleus | 3.85 | |
| SuperiorCervicalGanglion | 4.65 | |
| TemporalLobe | 3.75 | |
| Testis | 3.55 | |
| TestisGermCell | 3.35 | |
| TestisIntersitial | 3.45 | |
| TestisLeydigCell | 4.05 | |
| TestisSeminiferousTubule | 3.5 | |
| Thalamus | 4.2 | |
| Thymus | 3.25 | |
| Thyroid | 4.95 | |
| Tongue | 4 | |
| Tonsil | 12.7 | |
| Trachea | 3.4 | |
| TrigeminalGanglion | 4.45 | |
| Uterus | 3.3 | |
| UterusCorpus | 3.9 | |
| WholeBlood | 38.15 | |
| Wholebrain | 3.35 | |
| colon | 4.15 | |
| pineal_day | 5.08 | |
| pineal_night | 5 | |
| retina | 5.825 | |
| small_intestine | 3.95 | |
- Probe name: CUST_1285_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.46 ± 0.61 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.4 ± 0.51 | |
| Basal Part of Pons | 5.13 ± 0.29 | |
| Cerebellar Cortex | 4.85 ± 0.48 | |
| Cerebellar Nuclei | 5.53 ± 0.41 | |
| Claustrum | 5.35 ± 0.91 | |
| Epithalamus | 5.46 ± 0.46 | |
| Frontal Lobe | 5.14 ± 0.51 | |
| Globus Pallidus | 5.9 ± 0.42 | |
| Hypothalamus | 5.33 ± 0.44 | |
| Insula | 5.02 ± 0.41 | |
| Limbic Lobe | 5.07 ± 0.54 | |
| Mesencephalon | 5.18 ± 0.49 | |
| Myelencephalon | 5.26 ± 0.52 | |
| Occipital Lobe | 5.25 ± 0.61 | |
| Parietal Lobe | 5.05 ± 0.5 | |
| Pontine Tegmentum | 4.97 ± 0.54 | |
| Striatum | 5.4 ± 0.52 | |
| Subthalamus | 5.14 ± 0.6 | |
| Temporal Lobe | 5.05 ± 0.57 | |
| Thalamus | 5.16 ± 0.44 | |
| White Matter | 5.81 ± 0.26 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Inpp5d | CB | Cerebellum | 2.22 | |
| 3.6 | | |||
| Inpp5d | CTX | Cerebral cortex | 3.31 | |
| 2.75 | | |||
| Inpp5d | HIP | Hippocampal region | 2.15 | |
| 2.25 | | |||
| Inpp5d | HPF | Hippocampal formation | 2.95 | |
| 2.74 | | |||
| Inpp5d | HY | Hypothalamus | 0.64 | |
| 0.45 | | |||
| Inpp5d | LSX | Lateral septal complex | 0.25 | |
| 0.14 | | |||
| Inpp5d | MB | Midbrain | 3.51 | |
| 5.04 | | |||
| Inpp5d | MY | Medulla | 0.94 | |
| 0.98 | | |||
| Inpp5d | OLF | Olfactory bulb | 3.46 | |
| 2.63 | | |||
| Inpp5d | P | Pons | 1.14 | |
| 1.02 | | |||
| Inpp5d | PAL | Pallidum | 0.34 | |
| 0.21 | | |||
| Inpp5d | RHP | Retrohippocampal region | 4.02 | |
| 3.25 | | |||
| Inpp5d | sAMY | Striatum-like amygdalar nuclei | 0.24 | |
| 0.2 | | |||
| Inpp5d | STR | Striatum | 0.66 | |
| 0.46 | | |||
| Inpp5d | STRd | Striatum dorsal region | 0.65 | |
| 0.47 | | |||
| Inpp5d | STRv | Striatum ventral region | 1.11 | |
| 0.62 | | |||
| Inpp5d | TH | Thalamus | 1.6 | |
| 1.26 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00004253 | 20 | 1045 | 1064 | KEPPPCPEPGILSPSIVLTK | Peptide Atlas |