AutismKB 2.0

Annotation Detail for INPPL1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:INPPL1 ( SHIP2 )
Gene Full Name: inositol polyphosphate phosphatase-like 1
Band: 11q13.4
Quick LinksEntrez ID:3636; OMIM: 600829; Uniprot ID:SHIP2_HUMAN; ENSEMBL ID: ENSG00000165458; HGNC ID: 6080
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body15 / 70761211
blastocyst10 / 62319160
fetus25 / 56401244
neonate1 / 3109732
infant3 / 23620127
juvenile1 / 5555617
adult183 / 193912194
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma5 / 17475286
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma8 / 8282396
colorectal tumor18 / 114246157
esophageal tumor3 / 17290173
gastrointestinal tumor9 / 11936975
germ cell tumor23 / 26384587
glioma11 / 106883102
head and neck tumor10 / 13630273
kidney tumor4 / 6895958
leukemia15 / 95842156
liver tumor3 / 9635931
lung tumor27 / 103127261
lymphoma7 / 7175597
non-neoplasia5 / 9725051
normal247 / 336030773
ovarian tumor6 / 7668278
pancreatic tumor26 / 104616248
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer5 / 10268048
retinoblastoma5 / 46356107
skin tumor11 / 12494988
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites2 / 4001549
bladder3 / 29757100
blood11 / 12347889
bone5 / 7165569
bone marrow4 / 4880181
brain44 / 110098939
cervix4 / 4817183
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue36 / 215722166
esophagus3 / 20209148
eye34 / 211054161
heart2 / 8962622
intestine28 / 234472119
kidney18 / 21177784
larynx1 / 2414541
liver3 / 20774314
lung58 / 336974172
lymph3 / 4427067
lymph node15 / 91610163
mammary gland7 / 15327145
mouth6 / 6705289
muscle5 / 10771546
nerve6 / 15768380
ovary9 / 10205188
pancreas28 / 214812130
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta46 / 280825163
prostate21 / 189345110
salivary gland3 / 20155148
skin16 / 21057475
spleen3 / 5395255
stomach7 / 9661972
testis5 / 33044215
thymus6 / 8113173
thyroid4 / 4747384
tonsil3 / 16999176
trachea2 / 5241338
umbilical cord0 / 136800 
uterus22 / 23287894
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201598_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts30.6
Adipocyte5.45
AdrenalCortex6.25
Adrenalgland4.75
Amygdala5.9
Appendix5.4
AtrioventricularNode4.1
BDCA4+_DentriticCells36.55
Bonemarrow5.6
BronchialEpithelialCells6.3
CD105+_Endothelial23.05
CD14+_Monocytes60.55
CD19+_BCells(neg._sel.)22.85
CD33+_Myeloid113.75
CD34+52.35
CD4+_Tcells31.95
CD56+_NKCells58.8
CD71+_EarlyErythroid7.45
CD8+_Tcells38.15
CardiacMyocytes8.3
Caudatenucleus4.8
Cerebellum4.3
CerebellumPeduncles6.05
CiliaryGanglion3.75
CingulateCortex5.5
Colorectaladenocarcinoma12.55
DorsalRootGanglion4.15
FetalThyroid7.25
Fetalbrain5.4
Fetalliver4.65
Fetallung9.95
GlobusPallidus4
Heart12.55
Hypothalamus6.4
Kidney4.5
Leukemia_chronicMyelogenousK-5628.3
Leukemia_promyelocytic-HL-6011.8
Leukemialymphoblastic(MOLT-4)7.9
Liver7.15
Lung6.65
Lymphnode6.05
Lymphoma_burkitts(Daudi)7.1
Lymphoma_burkitts(Raji)53.8
MedullaOblongata4.9
OccipitalLobe4.8
OlfactoryBulb5.25
Ovary3.55
Pancreas4.6
PancreaticIslet5.85
ParietalLobe5.65
Pituitary6.45
Placenta23.55
Pons5.2
PrefrontalCortex6.85
Prostate19.6
Salivarygland4.3
SkeletalMuscle6.55
Skin4.15
SmoothMuscle10.75
Spinalcord8.2
SubthalamicNucleus4.95
SuperiorCervicalGanglion5.95
TemporalLobe4.85
Testis4.6
TestisGermCell4.6
TestisIntersitial4.5
TestisLeydigCell5.4
TestisSeminiferousTubule4.6
Thalamus5.85
Thymus4.4
Thyroid17.15
Tongue5.55
Tonsil5.5
Trachea4.6
TrigeminalGanglion5.35
Uterus14.15
UterusCorpus4.95
WholeBlood8.7
Wholebrain4.55
colon5.5
pineal_day13.16
pineal_night8.3
retina11.4
small_intestine5.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12400_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.45 ± 0.93
Basal Forebrain1.81 ± 0.32
Basal Part of Pons1.73 ± 0.39
Cerebellar Cortex1.83 ± 0.69
Cerebellar Nuclei2.5 ± 0.65
Claustrum2.69 ± 0.84
Epithalamus2.65 ± 0.23
Frontal Lobe2.04 ± 0.73
Globus Pallidus3.45 ± 0.73
Hypothalamus2.04 ± 0.8
Insula2.02 ± 0.83
Limbic Lobe2.05 ± 0.83
Mesencephalon2.34 ± 0.64
Myelencephalon2.25 ± 0.73
Occipital Lobe2.44 ± 0.8
Parietal Lobe2.2 ± 0.72
Pontine Tegmentum2.23 ± 0.81
Striatum2.23 ± 0.78
Subthalamus2.73 ± 0.14
Temporal Lobe2.01 ± 0.68
Thalamus2.34 ± 0.55
White Matter2.62 ± 1.05
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Inppl1CBCerebellum10.57
11.24
Inppl1CTXCerebral cortex16.76
7.42
Inppl1HIPHippocampal region6
4.9
Inppl1HPFHippocampal formation5.8
4.25
Inppl1HYHypothalamus2.86
1.77
Inppl1LSXLateral septal complex5.83
3.7
Inppl1MBMidbrain3.53
2.7
Inppl1MYMedulla6.07
4.1
Inppl1OLFOlfactory bulb18.92
10.53
Inppl1PPons3.83
2.31
Inppl1PALPallidum5.39
3.92
Inppl1RHPRetrohippocampal region5.28
3.37
Inppl1sAMYStriatum-like amygdalar nuclei4.23
2.4
Inppl1STRStriatum7.93
4.34
Inppl1STRdStriatum dorsal region9.53
5.25
Inppl1STRvStriatum ventral region5.61
2.9
Inppl1THThalamus4.14
2.73
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00073289 18 961 978 LKPEGAPEPEGVAAPPPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved