Annotation Detail for IRAK2
Basic Information Top
| Gene Symbol: | IRAK2 ( IRAK-2,MGC150550 ) |
|---|---|
| Gene Full Name: | interleukin-1 receptor-associated kinase 2 |
| Band: | 3p25.3 |
| Quick Links | Entrez ID:3656; OMIM: 603304; Uniprot ID:IRAK2_HUMAN; ENSEMBL ID: ENSG00000134070; HGNC ID: 6113 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.449207
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 2 / 564012 | 3 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 19 / 1939121 | 9 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 17 / 3360307 | 5 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 2 / 29757 | 67 |  |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 12 / 1100989 | 10 | |
| cervix | 4 / 48171 | 83 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 | |
| lung | 6 / 336974 | 17 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 2 / 96619 | 20 | |
| testis | 2 / 330442 | 6 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_13975_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.47 ± 0.86 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.24 ± 0.65 | |
| Basal Part of Pons | 3.2 ± 0.89 | |
| Cerebellar Cortex | 3.39 ± 0.48 | |
| Cerebellar Nuclei | 3.65 ± 0.65 | |
| Claustrum | 3.36 ± 0.76 | |
| Epithalamus | 2.68 ± 0.76 | |
| Frontal Lobe | 2.99 ± 0.73 | |
| Globus Pallidus | 3.92 ± 0.65 | |
| Hypothalamus | 3.45 ± 0.63 | |
| Insula | 2.95 ± 0.54 | |
| Limbic Lobe | 3.04 ± 0.74 | |
| Mesencephalon | 3.29 ± 0.71 | |
| Myelencephalon | 3.15 ± 0.76 | |
| Occipital Lobe | 3.48 ± 0.91 | |
| Parietal Lobe | 3.06 ± 0.69 | |
| Pontine Tegmentum | 3.22 ± 0.62 | |
| Striatum | 2.84 ± 0.87 | |
| Subthalamus | 3.22 ± 0.24 | |
| Temporal Lobe | 3.05 ± 0.73 | |
| Thalamus | 3.23 ± 0.6 | |
| White Matter | 4.83 ± 0.5 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Irak2 | CB | Cerebellum | 7.55 | |
| 9.23 | | |||
| Irak2 | CTX | Cerebral cortex | 5.08 | |
| 3.39 | | |||
| Irak2 | HIP | Hippocampal region | 2.5 | |
| 2.79 | | |||
| Irak2 | HPF | Hippocampal formation | 3.42 | |
| 3.14 | | |||
| Irak2 | HY | Hypothalamus | 0.13 | |
| 0.1 | | |||
| Irak2 | LSX | Lateral septal complex | 0 | |
| 0 | | |||
| Irak2 | MB | Midbrain | 0.85 | |
| 1.4 | | |||
| Irak2 | MY | Medulla | 0.68 | |
| 0.71 | | |||
| Irak2 | OLF | Olfactory bulb | 6.32 | |
| 4.15 | | |||
| Irak2 | P | Pons | 1.12 | |
| 1.17 | | |||
| Irak2 | PAL | Pallidum | 0.31 | |
| 0.26 | | |||
| Irak2 | RHP | Retrohippocampal region | 4.4 | |
| 3.37 | | |||
| Irak2 | sAMY | Striatum-like amygdalar nuclei | 0.15 | |
| 0.24 | | |||
| Irak2 | STR | Striatum | 1.02 | |
| 0.67 | | |||
| Irak2 | STRd | Striatum dorsal region | 1.04 | |
| 0.68 | | |||
| Irak2 | STRv | Striatum ventral region | 1.38 | |
| 0.84 | | |||
| Irak2 | TH | Thalamus | 2.27 | |
| 2.54 | |