AutismKB 2.0

Annotation Detail for ITGA3


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Basic Information Top
Gene Symbol:ITGA3 ( CD49C,FLJ34631,FLJ34704,GAP-B3,GAPB3,MSK18,VCA-2,VL3A,VLA3a )
Gene Full Name: integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Band: 17q21.33
Quick LinksEntrez ID:3675; OMIM: 605025; Uniprot ID:ITA3_HUMAN; ENSEMBL ID: ENSG00000005884; HGNC ID: 6139
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst1 / 6231916
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile12 / 55556215
adult362 / 1939121186
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma10 / 17475572
breast (mammary gland) tumor9 / 9417895
cervical tumor3 / 3436687
chondrosarcoma24 / 82823289
colorectal tumor22 / 114246192
esophageal tumor3 / 17290173
gastrointestinal tumor15 / 119369125
germ cell tumor5 / 26384518
glioma18 / 106883168
head and neck tumor29 / 136302212
kidney tumor85 / 689591232
leukemia1 / 9584210
liver tumor20 / 96359207
lung tumor37 / 103127358
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal177 / 336030752
ovarian tumor12 / 76682156
pancreatic tumor42 / 104616401
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer49 / 102680477
retinoblastoma0 / 463560 
skin tumor13 / 124949104
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor13 / 90257144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites2 / 4001549
bladder11 / 29757369
blood3 / 12347824
bone18 / 71655251
bone marrow1 / 4880120
brain51 / 110098946
cervix4 / 4817183
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue18 / 21572283
esophagus3 / 20209148
eye18 / 21105485
heart0 / 896260 
intestine33 / 234472140
kidney105 / 211777495
larynx6 / 24145248
liver21 / 207743101
lung51 / 336974151
lymph0 / 442700 
lymph node0 / 916100 
mammary gland21 / 153271137
mouth4 / 6705259
muscle4 / 10771537
nerve3 / 15768190
ovary14 / 102051137
pancreas43 / 214812200
parathyroid0 / 205390 
pharynx6 / 41328145
pituitary gland0 / 165850 
placenta22 / 28082578
prostate51 / 189345269
salivary gland0 / 201550 
skin21 / 21057499
spleen1 / 5395218
stomach12 / 96619124
testis4 / 33044212
thymus2 / 8113124
thyroid17 / 47473358
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus106 / 232878455
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: Primary tumors (U95A)
  • Affymatrix Probe ID: 884_at
Cell line Expression level Expression bar
Pr1T21.262
Pr4T23.348
Pr5T22.716
Pr7T24.61
Pr1N25.618
Pr5N23.222
Pr6T22.618
Pr3N23.682
Pr3T24.875
Pr4N24.616
Pr2N25.787
Pr8N23.064
Pr8T19.525
Pr9N23.32
Pr10N24.359
Pr10T22.248
Pr9T22.273
Pr11T20.78
Pr12T18.444
Pr13AT18.021
Pr13BT20.894
Pr21T20.077
Pr22T21.19
Pr30T25.994
Pr23T11.003
Pr19T19.394
Pr26T25.397
Pr31T21.658
Pr16T19.949
Pr17T23.461
Pr24T18.097
Pr27T20.121
Pr29T19.113
OVR10238.487
HUOVR23.492
G2202.837
G327.154
G531.455
G621.064
G8360.242
G9148.469
CO7T27.308
CO8T24.333
CO15T30.565
CO27T27.075
CO30T23.218
CO32T31.066
CO40T33.017
CO52N34.296
CO62N25.67
K142.367
K273.455
K330.725
K464.75
K14N32.446
K1640.321
K1725.618
K1938.602
K2049.387
K22137.744
CO9T55.573
CO20T28.534
CO24T52.328
CO36N31.287
K18159.58
P1N22.489
P2N25.363
P5N25.426
P889.454
P11171.239
P1726.458
K21147.796
K25N60.408
K28N80.857
CO42T26.296
P2278.865
P13N453.254
LU11T330.875
LU16T27.366
LU7T24.171
LU8T942.07
LU12T53.557
LU13T30.445
LU5T224.307
LU6T49.428
LU14T27.136
LU17T528.431
LU50N81.218
LU52N139.928
LU18T61.993
LU55N124.672
LU3N96.663
P16B256.715
P2334.377
OVR1629.117
OVR19190.826
OVR2728.485
OVR2838.27
OVR278E23.457
OVR223.232
OVR524.774
OVR832.537
OVR1127.765
OVR1225.333
OVR1325.566
OVR22183.76
OVR26447.62
OVR1072.527
OVR278S21.603
OVR194.954
LU19T22.481
LU20T42.371
LU24T26.465
LU25T50.255
LU31T115.893
LU34T26.225
LU39T19.887
CO14T26.717
CO21T30.952
CO23T26.558
CO41N25.348
LU40T98.41
LU41T22.943
LU44T104.854
LU46T27.4
LU49T461.849
L5N25.217
LU42T26.053
LU30T96.64
LU43T38.075
CO5T28.543
CO44T24.93
CO49T24.744
CO51T26.518
CO56T25.518
CO61T25.441
LU26T31.054
LU33T214.487
LU36T36.687
CO43T29.214
G1822.208
G4624.335
L11T22.031
L13N24.373
L30T24.533
L31T30.464
L32T25.199
L34T32.927
L35T30.129
B1N27.219
B5N26.089
B8T26.641
B10T26.302
B14T25.929
B16T23.4
B17T23.912
B1NR25.38
B20T34.202
B51NR24.517
B6T24.586
B15T39.923
B21T26.444
B29T37.668
B31T91.827
B32T29.932
B24T23.162
B46T27.864
B34T25.564
B36T27.217
B37T25.346
B38T24.844
B39T21.526
X10225.008
X116_0221.023
G28023.087
X4619.032
X5820.191
G18618.904
G29623.715
L38T26.554
L31T.2341.937
L26N29.738
N257ANTR25.705
N285BODY368.575
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14989_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.75 ± 1.03
Basal Forebrain1.28 ± 0.24
Basal Part of Pons1.2 ± 0.93
Cerebellar Cortex1.36 ± 0.75
Cerebellar Nuclei1.58 ± 0.74
Claustrum2.05 ± 0.72
Epithalamus1.07 ± 0.72
Frontal Lobe1.19 ± 0.67
Globus Pallidus1.85 ± 0.58
Hypothalamus1.35 ± 0.75
Insula1.14 ± 0.47
Limbic Lobe1.2 ± 0.64
Mesencephalon1.5 ± 0.75
Myelencephalon1.37 ± 0.65
Occipital Lobe1.28 ± 0.7
Parietal Lobe1.36 ± 0.85
Pontine Tegmentum1.34 ± 0.73
Striatum1.22 ± 0.68
Subthalamus1.36 ± 0.64
Temporal Lobe1.35 ± 0.77
Thalamus1.25 ± 0.64
White Matter1.32 ± 0.32
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ITA3_HUMAN_277 17 277 293 HMGAVFLLSQEAGGDLR PRIDE
ITA3_HUMAN_531 19 531 549 FAGSESAVFHGFFSMPEMR PRIDE
ITA3_HUMAN_553 10 553 562 LELLLMDNLR PRIDE
ITA3_HUMAN_771 16 771 786 LQSFFGGTVMGESGMK PRIDE
PAp00007699 13 88 100 TGAVYLCPLTAHK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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