AutismKB 2.0

Annotation Detail for ITIH1


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Basic Information Top
Gene Symbol:ITIH1 ( H1P,IATIH,IGHEP1,ITIH,MGC126415,SHAP )
Gene Full Name: inter-alpha (globulin) inhibitor H1
Band: 3p21.1
Quick LinksEntrez ID:3697; OMIM: 147270; Uniprot ID:ITIH1_HUMAN; ENSEMBL ID: ENSG00000055957; HGNC ID: 6166
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus71 / 564012125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult68 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor38 / 96359394
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal156 / 336030746
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart2 / 8962622
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver137 / 207743659
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland9 / 15327158
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen4 / 5395274
stomach0 / 966190 
testis0 / 3304420 
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210888_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.2
Adipocyte8.15
AdrenalCortex5.25
Adrenalgland4.35
Amygdala5.2
Appendix5.15
AtrioventricularNode3.9
BDCA4+_DentriticCells5.55
Bonemarrow5.05
BronchialEpithelialCells4.85
CD105+_Endothelial5.05
CD14+_Monocytes5.25
CD19+_BCells(neg._sel.)5.4
CD33+_Myeloid6.4
CD34+6.3
CD4+_Tcells5.4
CD56+_NKCells6
CD71+_EarlyErythroid4.7
CD8+_Tcells4.8
CardiacMyocytes6.45
Caudatenucleus4.55
Cerebellum4.1
CerebellumPeduncles5.75
CiliaryGanglion3.55
CingulateCortex5.2
Colorectaladenocarcinoma5.05
DorsalRootGanglion3.9
FetalThyroid4.85
Fetalbrain5.05
Fetalliver900.8
Fetallung169.1
GlobusPallidus3.75
Heart6.8
Hypothalamus5.45
Kidney4.15
Leukemia_chronicMyelogenousK-5624.55
Leukemia_promyelocytic-HL-604.45
Leukemialymphoblastic(MOLT-4)4.05
Liver2835
Lung5.5
Lymphnode4.4
Lymphoma_burkitts(Daudi)6.55
Lymphoma_burkitts(Raji)7.25
MedullaOblongata4.55
OccipitalLobe4.5
OlfactoryBulb3.9
Ovary3.65
Pancreas4.1
PancreaticIslet5.4
ParietalLobe5.35
Pituitary5.85
Placenta5
Pons4.8
PrefrontalCortex6.05
Prostate5.9
Salivarygland4
SkeletalMuscle6.05
Skin4.9
SmoothMuscle5.6
Spinalcord5.45
SubthalamicNucleus4.65
SuperiorCervicalGanglion5.85
TemporalLobe4.6
Testis4.35
TestisGermCell4.05
TestisIntersitial4.2
TestisLeydigCell4.9
TestisSeminiferousTubule4.3
Thalamus5.15
Thymus4
Thyroid6.15
Tongue4.95
Tonsil4.9
Trachea4.25
TrigeminalGanglion4.9
Uterus4.05
UterusCorpus4.4
WholeBlood5.45
Wholebrain4.3
colon5.05
pineal_day6.18
pineal_night6.06
retina6.025
small_intestine4.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P136905
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.19 ± 0.72
Basal Forebrain7.88 ± 0.52
Basal Part of Pons7.55 ± 0.42
Cerebellar Cortex7.62 ± 0.53
Cerebellar Nuclei7.8 ± 0.31
Claustrum7.76 ± 0.32
Epithalamus7.4 ± 0.83
Frontal Lobe7.7 ± 0.51
Globus Pallidus7.95 ± 0.66
Hypothalamus7.68 ± 0.46
Insula7.73 ± 0.49
Limbic Lobe7.92 ± 0.63
Mesencephalon7.87 ± 0.61
Myelencephalon7.82 ± 0.6
Occipital Lobe8.33 ± 0.56
Parietal Lobe7.72 ± 0.57
Pontine Tegmentum7.72 ± 0.61
Striatum8.41 ± 0.59
Subthalamus7.28 ± 0.84
Temporal Lobe7.71 ± 0.7
Thalamus7.8 ± 0.58
White Matter8.48 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Itih1CBCerebellum0
0
Itih1CTXCerebral cortex0
0
Itih1HIPHippocampal region0
0
Itih1HPFHippocampal formation0
0
Itih1HYHypothalamus0
0
Itih1LSXLateral septal complex0
0
Itih1MBMidbrain0
0
Itih1MYMedulla0
0
Itih1OLFOlfactory bulb0
0
Itih1PPons0
0
Itih1PALPallidum0
0
Itih1RHPRetrohippocampal region0
0
Itih1sAMYStriatum-like amygdalar nuclei0
0
Itih1STRStriatum0
0
Itih1STRdStriatum dorsal region0
0
Itih1STRvStriatum ventral region0
0
Itih1THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00023972 12 126 137 AAISGENAGLVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018