Annotation Detail for ITPR2
Basic Information Top
| Gene Symbol: | ITPR2 ( IP3R2 ) |
|---|---|
| Gene Full Name: | inositol 1,4,5-triphosphate receptor, type 2 |
| Band: | 12p11.23 |
| Quick Links | Entrez ID:3709; OMIM: 600144; Uniprot ID:ITPR2_HUMAN; ENSEMBL ID: ENSG00000123104; HGNC ID: 6181 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.512235
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 2 / 62319 | 32 | |
| fetus | 34 / 564012 | 60 |  |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 9 / 55556 | 161 | |
| adult | 94 / 1939121 | 48 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 2 / 12794 | 156 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 6 / 94178 | 63 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 6 / 82823 | 72 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 4 / 263845 | 15 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 8 / 95842 | 83 | |
| liver tumor | 9 / 96359 | 93 | |
| lung tumor | 1 / 103127 | 9 |  |
| lymphoma | 7 / 71755 | 97 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 168 / 3360307 | 49 | |
| ovarian tumor | 5 / 76682 | 65 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 5 / 33197 | 150 | |
| ascites | 3 / 40015 | 74 | |
| bladder | 0 / 29757 | 0 | |
| blood | 5 / 123478 | 40 | |
| bone | 4 / 71655 | 55 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 15 / 1100989 | 13 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 6 / 149255 | 40 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 4 / 211054 | 18 | |
| heart | 1 / 89626 | 11 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 15 / 211777 | 70 | |
| larynx | 1 / 24145 | 41 | |
| liver | 21 / 207743 | 101 | |
| lung | 8 / 336974 | 23 | |
| lymph | 2 / 44270 | 45 | |
| lymph node | 14 / 91610 | 152 | |
| mammary gland | 16 / 153271 | 104 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 8 / 107715 | 74 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 9 / 214812 | 41 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 2 / 41328 | 48 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 13 / 280825 | 46 | |
| prostate | 4 / 189345 | 21 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 4 / 210574 | 18 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 4 / 96619 | 41 | |
| testis | 3 / 330442 | 9 | |
| thymus | 10 / 81131 | 123 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 5 / 52413 | 95 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 8 / 232878 | 34 | |
| vascular | 3 / 51780 | 57 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 202661_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.8 | |
| Adipocyte | 5 | |
| AdrenalCortex | 5.95 | |
| Adrenalgland | 4.3 | |
| Amygdala | 5.1 | |
| Appendix | 5.25 | |
| AtrioventricularNode | 4.05 | |
| BDCA4+_DentriticCells | 5.35 | |
| Bonemarrow | 4.95 | |
| BronchialEpithelialCells | 4.7 | |
| CD105+_Endothelial | 4.85 | |
| CD14+_Monocytes | 5.2 | |
| CD19+_BCells(neg._sel.) | 5.15 | |
| CD33+_Myeloid | 6.15 | |
| CD34+ | 6.1 | |
| CD4+_Tcells | 5.15 | |
| CD56+_NKCells | 5.7 | |
| CD71+_EarlyErythroid | 4.6 | |
| CD8+_Tcells | 4.6 | |
| CardiacMyocytes | 6.7 | |
| Caudatenucleus | 4.4 | |
| Cerebellum | 4 | |
| CerebellumPeduncles | 5.6 | |
| CiliaryGanglion | 3.7 | |
| CingulateCortex | 5.05 | |
| Colorectaladenocarcinoma | 4.9 | |
| DorsalRootGanglion | 3.9 | |
| FetalThyroid | 4.75 | |
| Fetalbrain | 4.8 | |
| Fetalliver | 4.35 | |
| Fetallung | 3.9 | |
| GlobusPallidus | 3.7 | |
| Heart | 6.7 | |
| Hypothalamus | 5.3 | |
| Kidney | 4.15 | |
| Leukemia_chronicMyelogenousK-562 | 4.4 | |
| Leukemia_promyelocytic-HL-60 | 4.35 | |
| Leukemialymphoblastic(MOLT-4) | 3.8 | |
| Liver | 6.65 | |
| Lung | 5.3 | |
| Lymphnode | 4.15 | |
| Lymphoma_burkitts(Daudi) | 6.45 | |
| Lymphoma_burkitts(Raji) | 7 | |
| MedullaOblongata | 4.4 | |
| OccipitalLobe | 4.35 | |
| OlfactoryBulb | 3.9 | |
| Ovary | 3.25 | |
| Pancreas | 4 | |
| PancreaticIslet | 5.25 | |
| ParietalLobe | 5.25 | |
| Pituitary | 5.7 | |
| Placenta | 4.9 | |
| Pons | 4.7 | |
| PrefrontalCortex | 6.05 | |
| Prostate | 5.65 | |
| Salivarygland | 6.05 | |
| SkeletalMuscle | 6.05 | |
| Skin | 3.95 | |
| SmoothMuscle | 5.55 | |
| Spinalcord | 6.6 | |
| SubthalamicNucleus | 4.55 | |
| SuperiorCervicalGanglion | 6 | |
| TemporalLobe | 4.55 | |
| Testis | 4.2 | |
| TestisGermCell | 3.95 | |
| TestisIntersitial | 4.15 | |
| TestisLeydigCell | 4.85 | |
| TestisSeminiferousTubule | 4.15 | |
| Thalamus | 5 | |
| Thymus | 3.8 | |
| Thyroid | 6 | |
| Tongue | 5 | |
| Tonsil | 4.8 | |
| Trachea | 4.2 | |
| TrigeminalGanglion | 5.1 | |
| Uterus | 3.9 | |
| UterusCorpus | 4.5 | |
| WholeBlood | 5.3 | |
| Wholebrain | 4.05 | |
| colon | 4.9 | |
| pineal_day | 6.06 | |
| pineal_night | 5.92 | |
| retina | 5.875 | |
| small_intestine | 4.7 | |
- Probe name: CUST_356_PI416408490
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.93 ± 0.37 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 7.78 ± 0.28 | |
| Basal Part of Pons | 7.42 ± 0.37 | |
| Cerebellar Cortex | 7.14 ± 0.22 | |
| Cerebellar Nuclei | 7.7 ± 0.21 | |
| Claustrum | 8.18 ± 0.64 | |
| Epithalamus | 8.3 ± 0.24 | |
| Frontal Lobe | 7.54 ± 0.42 | |
| Globus Pallidus | 8.68 ± 0.33 | |
| Hypothalamus | 7.69 ± 0.34 | |
| Insula | 7.49 ± 0.34 | |
| Limbic Lobe | 7.44 ± 0.55 | |
| Mesencephalon | 7.73 ± 0.42 | |
| Myelencephalon | 7.74 ± 0.39 | |
| Occipital Lobe | 8.04 ± 0.65 | |
| Parietal Lobe | 7.59 ± 0.41 | |
| Pontine Tegmentum | 7.65 ± 0.47 | |
| Striatum | 8.06 ± 0.33 | |
| Subthalamus | 7.46 ± 0.3 | |
| Temporal Lobe | 7.38 ± 0.37 | |
| Thalamus | 7.94 ± 0.32 | |
| White Matter | 7.76 ± 0.27 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Itpr2 | CB | Cerebellum | 18.1 | |
| 23.17 | | |||
| Itpr2 | CTX | Cerebral cortex | 13.98 | |
| 9.98 | | |||
| Itpr2 | HIP | Hippocampal region | 16.38 | |
| 15.74 | | |||
| Itpr2 | HPF | Hippocampal formation | 15.14 | |
| 13.26 | | |||
| Itpr2 | HY | Hypothalamus | 3.2 | |
| 2.54 | | |||
| Itpr2 | LSX | Lateral septal complex | 7.08 | |
| 4.95 | | |||
| Itpr2 | MB | Midbrain | 7.52 | |
| 6.93 | | |||
| Itpr2 | MY | Medulla | 13.57 | |
| 12.91 | | |||
| Itpr2 | OLF | Olfactory bulb | 13.01 | |
| 10.18 | | |||
| Itpr2 | P | Pons | 6.72 | |
| 7 | | |||
| Itpr2 | PAL | Pallidum | 7.71 | |
| 7.18 | | |||
| Itpr2 | RHP | Retrohippocampal region | 12.84 | |
| 9.74 | | |||
| Itpr2 | sAMY | Striatum-like amygdalar nuclei | 5.45 | |
| 3.78 | | |||
| Itpr2 | STR | Striatum | 7.09 | |
| 5.23 | | |||
| Itpr2 | STRd | Striatum dorsal region | 7.74 | |
| 5.89 | | |||
| Itpr2 | STRv | Striatum ventral region | 5.95 | |
| 3.9 | | |||
| Itpr2 | TH | Thalamus | 10.16 | |
| 8.09 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00000692 | 14 | 1350 | 1363 | ASFPILLHMMCSER | Peptide Atlas |