AutismKB 2.0

Annotation Detail for JAG2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:JAG2 ( HJ2,SER2 )
Gene Full Name: jagged 2
Band: 14q32.33
Quick LinksEntrez ID:3714; OMIM: 602570; Uniprot ID:JAG2_HUMAN; ENSEMBL ID: ENSG00000184916; HGNC ID: 6189
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus12 / 56401221
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor2 / 2638457
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal48 / 336030714
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain19 / 110098917
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye9 / 21105442
heart4 / 8962644
intestine9 / 23447238
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung10 / 33697429
lymph0 / 442700 
lymph node4 / 9161043
mammary gland8 / 15327152
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 32137_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.35
Adipocyte10.25
AdrenalCortex11
Adrenalgland6.05
Amygdala42.85
Appendix13.5
AtrioventricularNode7.75
BDCA4+_DentriticCells10.8
Bonemarrow12.6
BronchialEpithelialCells38.25
CD105+_Endothelial13.05
CD14+_Monocytes10.25
CD19+_BCells(neg._sel.)11.55
CD33+_Myeloid13.6
CD34+10.9
CD4+_Tcells11.65
CD56+_NKCells14.75
CD71+_EarlyErythroid11.55
CD8+_Tcells11.2
CardiacMyocytes13.65
Caudatenucleus18.8
Cerebellum12.7
CerebellumPeduncles18.75
CiliaryGanglion6.5
CingulateCortex21.2
Colorectaladenocarcinoma75
DorsalRootGanglion7.85
FetalThyroid13.45
Fetalbrain55.85
Fetalliver10.45
Fetallung19.25
GlobusPallidus10.85
Heart35.45
Hypothalamus59.7
Kidney8.6
Leukemia_chronicMyelogenousK-56228.5
Leukemia_promyelocytic-HL-6011.4
Leukemialymphoblastic(MOLT-4)10.3
Liver18.2
Lung84.6
Lymphnode11.6
Lymphoma_burkitts(Daudi)10.75
Lymphoma_burkitts(Raji)24.55
MedullaOblongata17.35
OccipitalLobe28.1
OlfactoryBulb10.65
Ovary6.05
Pancreas18.2
PancreaticIslet23.75
ParietalLobe19.1
Pituitary31.3
Placenta18.15
Pons18.95
PrefrontalCortex50.95
Prostate99.9
Salivarygland8.85
SkeletalMuscle12.65
Skin9.9
SmoothMuscle11.9
Spinalcord17.3
SubthalamicNucleus14.6
SuperiorCervicalGanglion13.35
TemporalLobe12.8
Testis14.1
TestisGermCell12.65
TestisIntersitial11.1
TestisLeydigCell12.5
TestisSeminiferousTubule11
Thalamus17.55
Thymus27.15
Thyroid38.1
Tongue15.1
Tonsil13.05
Trachea11.95
TrigeminalGanglion12.25
Uterus27.65
UterusCorpus11.6
WholeBlood12.65
Wholebrain24.2
colon13.5
pineal_day16.58
pineal_night15.04
retina17.325
small_intestine13.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13771_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.57 ± 0.76
Basal Forebrain3.29 ± 0.68
Basal Part of Pons3 ± 0.63
Cerebellar Cortex3.35 ± 0.51
Cerebellar Nuclei3.05 ± 0.6
Claustrum3.62 ± 0.72
Epithalamus3.07 ± 0.55
Frontal Lobe3.25 ± 0.59
Globus Pallidus3.15 ± 0.55
Hypothalamus3.01 ± 0.36
Insula3.15 ± 0.55
Limbic Lobe3.36 ± 0.6
Mesencephalon3.34 ± 0.68
Myelencephalon3.35 ± 0.53
Occipital Lobe3.57 ± 0.49
Parietal Lobe3.24 ± 0.55
Pontine Tegmentum3.25 ± 0.67
Striatum3.11 ± 0.7
Subthalamus3.03 ± 0.68
Temporal Lobe3.29 ± 0.62
Thalamus3.25 ± 0.51
White Matter2.99 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Jag2CBCerebellum10.65
11.94
Jag2CTXCerebral cortex29.57
19.85
Jag2HIPHippocampal region19.29
18.64
Jag2HPFHippocampal formation28.28
24.72
Jag2HYHypothalamus17.37
12.89
Jag2LSXLateral septal complex17.03
11.14
Jag2MBMidbrain15.27
12.75
Jag2MYMedulla23.86
24.24
Jag2OLFOlfactory bulb23.42
16
Jag2PPons17.54
16.99
Jag2PALPallidum12.61
9.97
Jag2RHPRetrohippocampal region43.55
33.42
Jag2sAMYStriatum-like amygdalar nuclei10.96
7.21
Jag2STRStriatum6.17
4.53
Jag2STRdStriatum dorsal region4.02
3.49
Jag2STRvStriatum ventral region8.25
5.01
Jag2THThalamus14.15
10.45
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00043056 27 585 611 VIDGCGSDAGPGMPGTAASGVCGPHGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved