AutismKB 2.0

Annotation Detail for JUN


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Basic Information Top
Gene Symbol:JUN ( AP-1,AP1,c-Jun )
Gene Full Name: jun proto-oncogene
Band: 1p32.1
Quick LinksEntrez ID:3725; OMIM: 165160; Uniprot ID:JUN_HUMAN; ENSEMBL ID: ENSG00000177606; HGNC ID: 6204
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst3 / 6231948
fetus87 / 564012154
neonate0 / 310970 
infant2 / 2362084
juvenile17 / 55556305
adult593 / 1939121305
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma15 / 82823181
colorectal tumor10 / 11424687
esophageal tumor1 / 1729057
gastrointestinal tumor104 / 119369871
germ cell tumor12 / 26384545
glioma45 / 106883421
head and neck tumor3 / 13630222
kidney tumor10 / 68959145
leukemia9 / 9584293
liver tumor5 / 9635951
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal725 / 3360307215
ovarian tumor17 / 76682221
pancreatic tumor18 / 104616172
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer19 / 102680185
retinoblastoma1 / 4635621
skin tumor9 / 12494972
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor38 / 90257421
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue17 / 131061297
adrenal gland2 / 3319760
ascites95 / 400152374
bladder0 / 297570 
blood12 / 12347897
bone9 / 71655125
bone marrow5 / 48801102
brain92 / 110098983
cervix6 / 48171124
connective tissue11 / 14925573
ear2 / 16212123
embryonic tissue10 / 21572246
esophagus1 / 2020949
eye26 / 211054123
heart16 / 89626178
intestine41 / 234472174
kidney27 / 211777127
larynx0 / 241450 
liver9 / 20774343
lung69 / 336974204
lymph0 / 442700 
lymph node5 / 9161054
mammary gland26 / 153271169
mouth0 / 670520 
muscle6 / 10771555
nerve17 / 157681078
ovary22 / 102051215
pancreas94 / 214812437
parathyroid23 / 205391119
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta31 / 280825110
prostate35 / 189345184
salivary gland0 / 201550 
skin13 / 21057461
spleen0 / 539520 
stomach9 / 9661993
testis16 / 33044248
thymus4 / 8113149
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus58 / 232878249
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201465_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.55
Adipocyte6.45
AdrenalCortex8.7
Adrenalgland5.8
Amygdala11.25
Appendix8.3
AtrioventricularNode5.65
BDCA4+_DentriticCells253.55
Bonemarrow6.95
BronchialEpithelialCells6.6
CD105+_Endothelial15.45
CD14+_Monocytes77.1
CD19+_BCells(neg._sel.)268
CD33+_Myeloid839.85
CD34+16.15
CD4+_Tcells10.05
CD56+_NKCells61
CD71+_EarlyErythroid6.4
CD8+_Tcells10.5
CardiacMyocytes8.5
Caudatenucleus5.95
Cerebellum5.6
CerebellumPeduncles7.8
CiliaryGanglion6.4
CingulateCortex6.85
Colorectaladenocarcinoma6.9
DorsalRootGanglion6.95
FetalThyroid6.55
Fetalbrain6.9
Fetalliver5.8
Fetallung15.95
GlobusPallidus5
Heart10.15
Hypothalamus7.25
Kidney6
Leukemia_chronicMyelogenousK-5626.1
Leukemia_promyelocytic-HL-605.9
Leukemialymphoblastic(MOLT-4)5.1
Liver9.35
Lung250.3
Lymphnode7.5
Lymphoma_burkitts(Daudi)8.6
Lymphoma_burkitts(Raji)9.8
MedullaOblongata5.95
OccipitalLobe5.85
OlfactoryBulb8.95
Ovary4.95
Pancreas8
PancreaticIslet7.35
ParietalLobe7.2
Pituitary9.5
Placenta6.8
Pons6.45
PrefrontalCortex9.7
Prostate43.55
Salivarygland5.4
SkeletalMuscle8.9
Skin5.5
SmoothMuscle7.85
Spinalcord13.7
SubthalamicNucleus6.15
SuperiorCervicalGanglion8.7
TemporalLobe6.25
Testis5.65
TestisGermCell5.6
TestisIntersitial5.8
TestisLeydigCell6.8
TestisSeminiferousTubule5.65
Thalamus6.8
Thymus6.45
Thyroid33
Tongue6.85
Tonsil6.45
Trachea17.65
TrigeminalGanglion7.75
Uterus19.85
UterusCorpus6.7
WholeBlood7.1
Wholebrain5.95
colon16.8
pineal_day8.1
pineal_night7.94
retina12.05
small_intestine11.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15654_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.85 ± 0.44
Basal Forebrain7.22 ± 0.16
Basal Part of Pons7.87 ± 0.35
Cerebellar Cortex7.6 ± 0.24
Cerebellar Nuclei8.17 ± 0.15
Claustrum7.59 ± 0.35
Epithalamus8.6 ± 0.61
Frontal Lobe7.64 ± 0.41
Globus Pallidus8.69 ± 0.24
Hypothalamus7.25 ± 0.8
Insula7.75 ± 0.33
Limbic Lobe7.72 ± 0.55
Mesencephalon7.52 ± 0.35
Myelencephalon7.59 ± 0.47
Occipital Lobe7.13 ± 0.49
Parietal Lobe7.41 ± 0.42
Pontine Tegmentum7.41 ± 0.53
Striatum7.27 ± 0.54
Subthalamus7.33 ± 0.21
Temporal Lobe7.71 ± 0.39
Thalamus7.45 ± 0.29
White Matter8.72 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
JunCBCerebellum100
100
JunCTXCerebral cortex100
100
JunHIPHippocampal region100
100
JunHPFHippocampal formation100
100
JunHYHypothalamus100
100
JunLSXLateral septal complex100
100
JunMBMidbrain100
100
JunMYMedulla100
100
JunOLFOlfactory bulb100
100
JunPPons100
100
JunPALPallidum100
100
JunRHPRetrohippocampal region100
100
JunsAMYStriatum-like amygdalar nuclei100
100
JunSTRStriatum100
100
JunSTRdStriatum dorsal region100
100
JunSTRvStriatum ventral region100
100
JunTHThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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