AutismKB 2.0

Annotation Detail for JUNB


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Basic Information Top
Gene Symbol:JUNB ( AP-1 )
Gene Full Name: jun B proto-oncogene
Band: 19p13.13
Quick LinksEntrez ID:3726; OMIM: 165161; Uniprot ID:JUNB_HUMAN; ENSEMBL ID: ENSG00000171223; HGNC ID: 6205
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus25 / 56401244
neonate2 / 3109764
infant0 / 236200 
juvenile6 / 55556107
adult432 / 1939121222
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor5 / 34366145
chondrosarcoma21 / 82823253
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor19 / 119369159
germ cell tumor2 / 2638457
glioma22 / 106883205
head and neck tumor5 / 13630236
kidney tumor5 / 6895972
leukemia11 / 95842114
liver tumor5 / 9635951
lung tumor10 / 10312796
lymphoma7 / 7175597
non-neoplasia21 / 97250215
normal500 / 3360307148
ovarian tumor16 / 76682208
pancreatic tumor18 / 104616172
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor14 / 124949112
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue8 / 13106610
adrenal gland7 / 33197210
ascites14 / 40015349
bladder1 / 2975733
blood20 / 123478161
bone17 / 71655237
bone marrow0 / 488010 
brain59 / 110098953
cervix16 / 48171332
connective tissue32 / 149255214
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye24 / 211054113
heart1 / 8962611
intestine16 / 23447268
kidney13 / 21177761
larynx0 / 241450 
liver6 / 20774328
lung43 / 336974127
lymph7 / 44270158
lymph node4 / 9161043
mammary gland21 / 153271137
mouth2 / 6705229
muscle0 / 1077150 
nerve7 / 15768443
ovary21 / 102051205
pancreas49 / 214812228
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland4 / 16585241
placenta68 / 280825242
prostate8 / 18934542
salivary gland3 / 20155148
skin26 / 210574123
spleen0 / 539520 
stomach6 / 9661962
testis5 / 33044215
thymus1 / 8113112
thyroid4 / 4747384
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord1 / 1368073
uterus15 / 23287864
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201473_at
Cell line Expression level Expression bar
721_B_lymphoblasts335.6
Adipocyte94.25
AdrenalCortex951.25
Adrenalgland551.15
Amygdala161.65
Appendix290
AtrioventricularNode167.8
BDCA4+_DentriticCells1273.05
Bonemarrow271.7
BronchialEpithelialCells219.5
CD105+_Endothelial468.8
CD14+_Monocytes2672.15
CD19+_BCells(neg._sel.)1113.6
CD33+_Myeloid3003.55
CD34+261.05
CD4+_Tcells1890.45
CD56+_NKCells1546.45
CD71+_EarlyErythroid242.3
CD8+_Tcells1005.5
CardiacMyocytes98.1
Caudatenucleus104.7
Cerebellum97.8
CerebellumPeduncles151.8
CiliaryGanglion373.25
CingulateCortex61.75
Colorectaladenocarcinoma385.6
DorsalRootGanglion125.15
FetalThyroid71.3
Fetalbrain114.3
Fetalliver124.95
Fetallung258.65
GlobusPallidus53.85
Heart306.95
Hypothalamus151.25
Kidney191.6
Leukemia_chronicMyelogenousK-562147.05
Leukemia_promyelocytic-HL-60255.3
Leukemialymphoblastic(MOLT-4)64.75
Liver152.75
Lung1952.05
Lymphnode224.75
Lymphoma_burkitts(Daudi)94.1
Lymphoma_burkitts(Raji)536.45
MedullaOblongata112.3
OccipitalLobe133.65
OlfactoryBulb658.6
Ovary292.55
Pancreas220.9
PancreaticIslet371.9
ParietalLobe77.6
Pituitary431.2
Placenta336.3
Pons115.45
PrefrontalCortex119.25
Prostate842.7
Salivarygland51.2
SkeletalMuscle102.95
Skin172.75
SmoothMuscle139.85
Spinalcord440.25
SubthalamicNucleus75.35
SuperiorCervicalGanglion183.8
TemporalLobe92.7
Testis72.5
TestisGermCell206.05
TestisIntersitial89.65
TestisLeydigCell79.6
TestisSeminiferousTubule91.35
Thalamus73.2
Thymus267.45
Thyroid876.2
Tongue284.15
Tonsil254.5
Trachea395.45
TrigeminalGanglion235.65
Uterus264.2
UterusCorpus347.4
WholeBlood1341.25
Wholebrain264.15
colon251.7
pineal_day316.18
pineal_night225.5
retina537
small_intestine139.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P241815
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.01 ± 0.63
Basal Forebrain3.69 ± 0.36
Basal Part of Pons3.86 ± 0.6
Cerebellar Cortex3.49 ± 0.38
Cerebellar Nuclei4.08 ± 0.31
Claustrum4.23 ± 0.82
Epithalamus4.47 ± 0.65
Frontal Lobe3.84 ± 0.57
Globus Pallidus4.8 ± 0.4
Hypothalamus3.49 ± 0.78
Insula3.82 ± 0.46
Limbic Lobe3.93 ± 0.56
Mesencephalon3.72 ± 0.61
Myelencephalon3.91 ± 0.61
Occipital Lobe3.89 ± 0.56
Parietal Lobe3.81 ± 0.64
Pontine Tegmentum3.8 ± 0.58
Striatum4.4 ± 0.47
Subthalamus3.63 ± 0.07
Temporal Lobe3.77 ± 0.56
Thalamus3.78 ± 0.51
White Matter4.11 ± 0.62
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
JunbCBCerebellum31.57
34.63
JunbCTXCerebral cortex25.71
19.8
JunbHIPHippocampal region27.44
24.08
JunbHPFHippocampal formation33.56
27.9
JunbHYHypothalamus15.8
12.21
JunbLSXLateral septal complex22.1
22.81
JunbMBMidbrain20.46
15.3
JunbMYMedulla28.9
27.02
JunbOLFOlfactory bulb55.4
39.24
JunbPPons20.14
18.45
JunbPALPallidum10.99
10.12
JunbRHPRetrohippocampal region50.45
38.25
JunbsAMYStriatum-like amygdalar nuclei20.88
22.23
JunbSTRStriatum22.31
18.19
JunbSTRdStriatum dorsal region17.48
13.5
JunbSTRvStriatum ventral region40.56
29.78
JunbTHThalamus15.22
11.13
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011922 16 328 343 VMTHVSNGCQLLLGVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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