AutismKB 2.0

Annotation Detail for TRIM23


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Basic Information Top
Gene Symbol:TRIM23 ( ARD1,ARFD1,RNF46 )
Gene Full Name: tripartite motif-containing 23
Band: 5q12.3
Quick LinksEntrez ID:373; OMIM: 601747; Uniprot ID:TRI23_HUMAN; ENSEMBL ID: ENSG00000113595; HGNC ID: 660
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus15 / 56401226
neonate1 / 3109732
infant2 / 2362084
juvenile1 / 5555617
adult30 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal110 / 336030732
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone2 / 7165527
bone marrow3 / 4880161
brain81 / 110098973
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung0 / 3369740 
lymph0 / 442700 
lymph node5 / 9161054
mammary gland5 / 15327132
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach3 / 9661931
testis9 / 33044227
thymus4 / 8113149
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus4 / 23287817
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210994_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.4
Adipocyte5.8
AdrenalCortex6.5
Adrenalgland5.1
Amygdala10.2
Appendix6.4
AtrioventricularNode5.2
BDCA4+_DentriticCells5.9
Bonemarrow6.1
BronchialEpithelialCells5.6
CD105+_Endothelial5.75
CD14+_Monocytes6.2
CD19+_BCells(neg._sel.)6.45
CD33+_Myeloid7.8
CD34+7.6
CD4+_Tcells6.55
CD56+_NKCells7.1
CD71+_EarlyErythroid9.7
CD8+_Tcells5.95
CardiacMyocytes9
Caudatenucleus5.4
Cerebellum4.85
CerebellumPeduncles6.9
CiliaryGanglion4.65
CingulateCortex7.3
Colorectaladenocarcinoma5.95
DorsalRootGanglion4.75
FetalThyroid6.1
Fetalbrain6.05
Fetalliver6.1
Fetallung4.9
GlobusPallidus4.5
Heart8.4
Hypothalamus6.65
Kidney5.05
Leukemia_chronicMyelogenousK-5625.3
Leukemia_promyelocytic-HL-605.35
Leukemialymphoblastic(MOLT-4)4.55
Liver8.3
Lung6.55
Lymphnode5.05
Lymphoma_burkitts(Daudi)7.7
Lymphoma_burkitts(Raji)8.65
MedullaOblongata5.5
OccipitalLobe5.6
OlfactoryBulb4.75
Ovary4.5
Pancreas4.85
PancreaticIslet6.5
ParietalLobe6.95
Pituitary7.15
Placenta5.85
Pons5.75
PrefrontalCortex7.25
Prostate6.8
Salivarygland4.85
SkeletalMuscle8.65
Skin4.85
SmoothMuscle6.8
Spinalcord6.2
SubthalamicNucleus5.55
SuperiorCervicalGanglion8.9
TemporalLobe5.6
Testis5.1
TestisGermCell4.95
TestisIntersitial4.95
TestisLeydigCell6.25
TestisSeminiferousTubule5.05
Thalamus6.05
Thymus4.5
Thyroid7
Tongue6.05
Tonsil5.75
Trachea5.05
TrigeminalGanglion6.25
Uterus4.75
UterusCorpus6
WholeBlood6.7
Wholebrain5.05
colon5.95
pineal_day8.18
pineal_night7.36
retina7.3
small_intestine5.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P167384
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.21 ± 0.33
Basal Forebrain7.99 ± 0.3
Basal Part of Pons8.57 ± 0.22
Cerebellar Cortex8.2 ± 0.28
Cerebellar Nuclei8.15 ± 0.34
Claustrum8.24 ± 0.38
Epithalamus8.12 ± 0.42
Frontal Lobe8.36 ± 0.31
Globus Pallidus7.77 ± 0.32
Hypothalamus8.13 ± 0.32
Insula8.37 ± 0.33
Limbic Lobe8.36 ± 0.38
Mesencephalon8.2 ± 0.34
Myelencephalon8.23 ± 0.35
Occipital Lobe8.34 ± 0.34
Parietal Lobe8.42 ± 0.4
Pontine Tegmentum8.26 ± 0.33
Striatum7.95 ± 0.42
Subthalamus8.55 ± 0.44
Temporal Lobe8.34 ± 0.33
Thalamus8.23 ± 0.29
White Matter8.35 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Trim23CBCerebellum13.11
14.27
Trim23CTXCerebral cortex32.31
25.08
Trim23HIPHippocampal region26
32.21
Trim23HPFHippocampal formation25.72
27.24
Trim23HYHypothalamus4.56
3.84
Trim23LSXLateral septal complex10.73
8.41
Trim23MBMidbrain7.58
7
Trim23MYMedulla9.43
10.81
Trim23OLFOlfactory bulb24.22
19.39
Trim23PPons8.04
9.06
Trim23PALPallidum8.54
7.75
Trim23RHPRetrohippocampal region26.59
22.45
Trim23sAMYStriatum-like amygdalar nuclei7.97
6.39
Trim23STRStriatum10.53
7.78
Trim23STRdStriatum dorsal region11.41
8.48
Trim23STRvStriatum ventral region9.15
6.26
Trim23THThalamus12.54
11.46
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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