AutismKB 2.0

Annotation Detail for PEAR1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PEAR1 ( FLJ00193,JEDI,MEGF12 )
Gene Full Name: platelet endothelial aggregation receptor 1
Band: 1q23.1
Quick LinksEntrez ID:375033; OMIM: 610278; Uniprot ID:PEAR1_HUMAN; ENSEMBL ID: ENSG00000187800; HGNC ID: 33631
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus5 / 5640128
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult23 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal37 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye3 / 21105414
heart3 / 8962633
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach1 / 9661910
testis12 / 33044236
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P323901
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.69 ± 0.82
Basal Forebrain3.76 ± 0.3
Basal Part of Pons3.47 ± 0.63
Cerebellar Cortex3.34 ± 0.52
Cerebellar Nuclei4.03 ± 0.39
Claustrum4.08 ± 0.97
Epithalamus2.89 ± 0.4
Frontal Lobe3.55 ± 0.57
Globus Pallidus3.22 ± 0.61
Hypothalamus3.15 ± 0.47
Insula3.3 ± 0.81
Limbic Lobe3.57 ± 0.61
Mesencephalon3.57 ± 0.65
Myelencephalon3.63 ± 0.68
Occipital Lobe3.5 ± 0.69
Parietal Lobe3.55 ± 0.65
Pontine Tegmentum3.44 ± 0.65
Striatum3.49 ± 0.74
Subthalamus3.9 ± 0.14
Temporal Lobe3.58 ± 0.76
Thalamus3.58 ± 0.56
White Matter3.25 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
3110045G13RikCBCerebellum4.56
5.42
3110045G13RikCTXCerebral cortex3.52
2.43
3110045G13RikHIPHippocampal region1.42
1.16
3110045G13RikHPFHippocampal formation1.55
1.33
3110045G13RikHYHypothalamus1.61
1.16
3110045G13RikLSXLateral septal complex1.12
0.7
3110045G13RikMBMidbrain1.97
2.39
3110045G13RikMYMedulla5.29
5.26
3110045G13RikOLFOlfactory bulb7.94
5.65
3110045G13RikPPons4.46
4.97
3110045G13RikPALPallidum1.28
1.02
3110045G13RikRHPRetrohippocampal region1.86
1.57
3110045G13RiksAMYStriatum-like amygdalar nuclei1.21
1.28
3110045G13RikSTRStriatum1.38
1.04
3110045G13RikSTRdStriatum dorsal region1.15
0.9
3110045G13RikSTRvStriatum ventral region2.38
1.58
3110045G13RikTHThalamus1.67
1.29
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018